Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries by Pathadka, Swathi

“…Results: Consumption of systemic antifungal agents increased from 0.50 (in 2008) to 0.92 defined daily dose (DDD)/1000 inhabitants/day (in 2018), with a compound annual growth rate of 6.2%. …”
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Secreted Amyloid Precursor Protein β and Secreted Amyloid Precursor Protein α Induce Axon Outgrowth In Vitro through Egr1 Signaling Pathway by Stéphanie Chasseigneaux (231744)

“…</p> <h3>Methodology/Principal Findings</h3><p>Final concentrations of 50 to 150 nM bacterial recombinant sAPPα or sAPPβ added to primary neuronal cultures after 1 day in vitro decreased cell adhesion 24 hours later and primary dendrite length 96 hours later. 150 nM sAPPα and sAPPβ induced a similar increase of axon outgrowth, although this increase was already significant at 100 nM sAPPα. …”

DataSheet_1_E2F1 mediates competition, proliferation and response to cisplatin in cohabitating resistant and sensitive ovarian cancer cells.docx by Andres Valdivia (16546941)

“…Direct co-culture led to a decrease in the IC50 to platinum in the cisplatin-sensitive cells (5.92 µM to 2.79 µM for PE01, and from 2.05 µM to 1.51 µM for OVCAR5). …”

Analysis of DRD1 and DRD2 signalling upon dopamine treatment in SH-SY5Y-DRD1 or -DRD2 stable lines untransduced or transduced by WT or G2019S LRRK2. by Mauro Rassu (4068670)

“…<p><b>(A)</b> Cells stably expressing FLAG-tagged DRD1 were transduced by the different LRRK2 isoforms. 48h after transduction the cell were treated for different time points (15', 30', 60') by dopamine. …”

Data_Sheet_1_Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies.pdf by Eli Hatchwell (8584452)

“…</p>Conclusion<p>For the first time, a PML genetic risk test can be implemented for screening patients taking or considering treatment with a PML-linked drug in order to decrease the incidence of PML and enable safer use of highly effective therapies used to treat their underlying disease.…”

Contrast responses under stimulus contrasts distributing in different ranges. by Ming Hu (38573)

“…<i>B</i>: The mean response of the 33 cells to 50% contrast decreased when the mean of the contrast range increased. …”

Sequential action potentials vary in their amplitudes. by Na Chen (153323)

Myo1b kd reduces the number of SIT1 transporters at the apical plasma membrane. by Shigeru Komaba (794148)

“…The data are from three independent experiments and expressed as means ± s.e. *P<0.01, ** P<0.005. The expression of exogenous collectrin rescued the Myo1b-kd-induced decrease in SIT1-V5 at the APM. …”

The optimal number of clusters in the three datasets is evaluated parametrically. by Eric H. Yang (371822)

“…<p>It appears that after a certain point, the introduction of additional clusters appears to decrease the transcriptional state.…”

The effect of the filter size on the signal to noise ratio. by Anna Balkenius (326760)

“…<p>The signal to noise ratio increases with a larger filter up to a point where it starts to decrease again. …”

Loss of <i>Tbx4</i> and <i>Tbx5</i> causes reduced lung branching and lethality at birth. by Ripla Arora (145097)

“…<p>(A–H′) <i>Tbx4^fl</i> and <i>Tbx5^fl</i> alleles were excised using <i>CreER</i> by injecting tamoxifen at E8.75 and lungs were dissected at different time points. …”

Genome-wide association study of Streptococcus pneumoniae identifies disease-associated genetic variation by Shimin Yang (17308492)

“…First, a univariate LMM was fitted to initially screen infection-associated k-mers by the Pyseer (v1.3.10) Second, we used multiple methods (Scoary, LASSO and VSURF) to minimize false-positive associations and identify consensus infection-associated k-mers.The importance of k-mers was ranked by the mean decrease in impurity (Mean Decrease Gini, MDG), which is a measure of the predictor’s contribution to the correct sample classification.…”

Assessing the impact of climate changes on the distribution of two corn diseases: corn stunt and corn reddening by José Carlos Barbosa Dos Santos (21993507)

“…To do this, we developed two spatial distribution models for CS and CR. We found 193 points of occurrence for CS and 158 points for CR. …”

The results of screening the accurate strategy on the 23S-like rRNA datasets. by Yixiao Zhai (10181153)

“…<b>B</b> Sequential integration of initial alignments from MSA tools following ranking by aSP, Q, and TC scores. The ranking is derived from the "Mean" results of <b>A</b>. …”

Effect of long term depletion of Shield-1 in NF54::pS4-GFP-HA-DD24 cultures on <i>surf</i> gene transcription. by Tatiane Macedo-Silva (4351135)

“…<p>In <b>A</b>, dynamics of the <i>surf</i>4 and <i>surf</i>9 relative transcript quantity at given time points after removal and re-addition of Shield-1. …”

129S7-Ifngtm1Ts (IFN-γ) mice (b, d, f, h, k) by Katrin Neubauer (48437)

“…Sections of normal livers (a, b) or acutely damaged livers (after a single CCl-administration) at time points 12 h (c, d), 24 h (e, f), 48 h (g, h) and 72 h (i, k) are given. …”

Collecting ability of electret filters in collecting atomized protein particles. by Wang Li (283825)

“…Amounts of collected albumin increased as the volume of atomized albumin solution increased before point A, then decreased, and finally increased again after point B. …”

Data for green hotels paper by Vinh Pham (20850167)

“…Additionally, the counterfactual experiments indicate that requiring all regular hotels to achieve a medium level of green certification would increase their market share by around 13 percentage point, while removing all certification of green hotels would decrease their market share by around 14 percentage point. …”

Video_3_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Video_4_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”