Video_2_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Depleted pool of oNSCs and diminished neurogenesis in embryonic <i>BAF155</i>cKO OE. by Christina Bachmann (3111933)

“…Scale bars = 25 μm (A–C) and 50 μm (D–F).</p>…”

Data_Sheet_1_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.PDF by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Video_1_Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage.WMV by Danila Vella (7477892)

“…In particular, in the analyzed models, the impairment in contractility determined a decrease in SSR of about 50%, whilst the chamber pathological dilatation contributed to a 30% reduction, indicating increased risk of clot formation. …”

Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations by Mathew J. Barber (251595)

“…<div><h3>Background</h3><p>Statins effectively lower total and plasma LDL-cholesterol, but the magnitude of decrease varies among individuals. To identify single nucleotide polymorphisms (SNPs) contributing to this variation, we performed a combined analysis of genome-wide association (GWA) results from three trials of statin efficacy.…”

Best tumor response (waterfall plot) in evaluable patients (n = 24). by Shailender Bhatia (116286)

Transplanted MDSPCs assist in functional recovery of critically-sized sciatic nerve defects. by Mitra Lavasani (343357)

“…(<b>B-D</b>) Quantification of paw print analyses, indicating that MDSPC transplantation increases the ability of the mice to walk normally, displayed a (<b>B</b>) decrease in toe spread factor, (<b>C</b>) decrease in print length factor, and (<b>D</b>) an increase in SFI (sciatic functional index) compared to PBS-treated mice. …”

Dysplasia_Clinical.xlsx by Dani Gaillard (2744839)

“…Patients in Group 2 also benefited from a 19-minute decrease in mean operation time, a 45% decrease in mean estimated blood loss, and a 0.9-day decrease in mean hospital stay (p < 0.0001 in each instance). …”

Enzymatic activity of liver enzymes. by Torsten Diesinger (9159938)

“…<p><b>(a)</b> ALT is elevated by 71% and 50% compared to control groups 1 and 2. …”

Supporting datasets for all figures. by Matthew Drill (22258391)

“…This study examined the expression and function of P2X7R in a human glioblastoma cell line, U251. We used a pharmacological antagonist of P2X7R, AZ10606120, to inhibit receptor function and delineate downstream consequences of receptor inhibition. …”

Tau overload causes behavioral deficits and maintains neurodegeneration at older ages. by Kaushik Ghosal (244754)

“…<p>A. hTau animals also showed decreased working memory as measured by deficits in spontaneous alternations compared to age-matched wild-type animals. …”

FBW7 is degraded during <i>E</i>. <i>chaffeensis</i> infection. by Jennifer Y. Wang (8787527)

“…By day 2 pi, FBW7 levels decreased ~50% and ~70%, respectively compared to uninfected controls. …”

Impact of Environment and Social Gradient on <em>Leptospira</em> Infection in Urban Slums by Renato B. Reis (90436)

“…</p><h3>Methods and Findings</h3><p>We performed a community-based survey of 3,171 slum residents from Salvador, Brazil. …”

Genome-based model for differentiating between infection and carriage Staphylococcus aureus by JianYu Chen (19141864)

“…The importance of each k-mer predictor was sorted by the mean decrease in impurity (Mean Decrease Gini, MDG).…”

PC depolarization increases the number and reduces the onset latency of LTS APs. by Jie Zhu (126574)

“…(D) Comparison of the 1^st AP onset latency at resting versus depolarizing <i>V</i>_m. mean ± s.e.m. * <i>p</i><0.05. See also <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001032#pbio.1001032.s004" target="_blank">Figure S4</a>. …”

Dual Function of Histone H3 Lysine 36 Methyltransferase ASH1 in Regulation of Hox Gene Expression by Yujiro Tanaka (194756)

“…Notably, ASH1 harbouring a point mutation that kills methyltransferase activity is more efficient than wild type ASH1 in Hox gene activation, indicating that K36 methylation is not a prerequisite for Hox gene expression. …”

Hyperbaric oxygen therapy and comprehensive orthopedic treatment for incomplete traumatic spinal cord injury on the Qinghai-Tibet Plateau: study protocol for an open-label randomiz... by Jun Ma (4058161)

“…<div>Background: Apoptosis secondary to ischemia and hypoxia is the main cause of spinal cord dysfunction. Because of the decrease in atmospheric pressure, patients living on the Qinghai-Tibet Plateau are in a hypoxic environment, which is very unfavorable for the recovery of spinal cord injury. …”

CDA deficiency leads to excess dCTP, inhibiting PARP-1 activity and leading to UFB formation. by Simon Gemble (168663)

“…(G) (1) CDA deficiency leads to intracellular dCTP accumulation, decreasing basal PARP-1 activity. (2) The decrease in basal PARP-1 activity leads to an increase in unreplicated DNA sequences (preferentially at centromeres and CFS sites). (3) During late G2/early mitosis, some of this unreplicated DNA is probably processed by MUS81-EME1 and ERCC1 nucleases as previously suggested [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005384#pgen.1005384.ref036" target="_blank">36</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005384#pgen.1005384.ref012" target="_blank">12</a>], leading to DNA synthesis during metaphase (EdU foci) and preventing supernumerary UFB formation. (4) Some of the excess unreplicated DNA sequences are not processed by the nucleases, leading to supernumerary UFB formation.…”

Histopathological analysis of the non - tumour parenchyma following radical nephrectomy: can it predict renal functional outcome? by Rana Birendra (4658605)

“…Results 73 RN specimens were analyzed. Mean follow up was 12.3 months. The mean decrease in eGFR was 22% (p=.0001). …”

Mitotic phenotypes caused by co-depletion of CAMSAP2 and HAUS6. by Naoko Nishizawa (20536299)

“…<p>(A,B) Western blotting for γ-tubulin (A) and HAUS6 (B) in WT and CAMSAP2 KO cells. …”