Gadolinium-free Magnetic Resonance Imaging of the Liver via an Oatp1-Targeted Manganese(III) Porphyrin by Nivin N. Nyström (13118188)

“…Controversy surrounding gadolinium-based contrast agents (GBCAs) has rendered their continued utility highly contentious, but the liver-specific GBCA Gd­(III) ethoxybenzyl-diethylene triamine pentaacetic acid (Gd­(III)-EOB-DTPA) remains in use because it provides unique diagnostic information that could not be obtained by any other means. To address the need for an alternate liver-specific MRI probe, we synthesized Mn­(III) 20-(4-ethoxyphenyl) porphyrin-5,10,15-tricarboxylate (Mn­(III)­TriCP-PhOEt), which exhibited significantly higher <i>r</i>₁ relaxivity than Gd­(III)-EOB-DTPA in vitro, while also targeting hepatocyte-specific organic anion-transporting polypeptide 1 (Oatp1) channels as a marker of viability. …”

Polyampholyte−Surfactant Film Tuning in Reverse Microemulsions by Mabya Fechner (1943278)

“…Additionally, the required amount of surfactant to establish a clear w/o microemulsion depends on the pH value, which means the hydrophobicity of the copolymers. …”

Comparison of SPTAN1 in MLH1-proficient vs. MLH1-deficient CRCs. by Anne Ackermann (6443975)

“…SPTAN1 was significantly increased in MLH1-proficient tumors compared with the normal mucosa, while MLH1-deficient tumors showed a clear trend of decreased SPTAN1 levels compared with surrounding normal tissue. …”

Enforced expression of Mfn2 and DRP1 relieves Vpr-induced apoptosis. by Chih-Yang Huang (54970)

“…<b>D,</b> Overexpression of Mfn2, DRP1, and Mfn2/DRP1 reduced Vpr-induced apoptosis. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033657#s2" target="_blank">Results</a> are the means ± S.D. of three independent experiments. …”

Cardiac function of hearts expressing control PolyQ-25 and mutant PolyQ-46 affected differently by oxidant. by Girish C. Melkani (213588)

“…<p>(<b>A & B</b>) The already large systolic and diastolic heart diameters were further increased in the presence of the oxidant H₂O₂ in the hearts expressing PolyQ-46. …”

Genome-Wide Patterns of Gene Expression during Aging in the African Malaria Vector <em>Anopheles gambiae</em> by Mei-Hui Wang (203053)

“…<div><p>The primary means of reducing malaria transmission is through reduction in longevity in days of the adult female stage of the <em>Anopheles</em> vector. …”

T cell survival is regulated by DUSP5. by Raman G. Kutty (3390200)

“…Plots are means with error bars ±SEM. Comparisons were made using a two-tailed t-test, *: p<0.05, **: p<0.01 ***: p<0.005.…”

Differences in lipid mediators between sPTB and FTB in obese and underweight groups. by Kamil Borkowski (629694)

“…Saturated and monounsaturated fatty acids were not measured in this assay and are indicated only to visualize parent fatty acids for measured oxylipins and endocannabinoids. Means of individual metabolites and corresponding p-values are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0239115#pone.0239115.s003" target="_blank">S2 Table</a>.…”

Assessment of B cell development in the BM of transgenic mice. by Ying Xing (278605)

“…<p>BM cells from the indicated mouse strains were stained with anti-B220, anti-CD43, and anti-IgM, and were analyzed by FACS. (A) The gates in panels represent Hardy fractions A-D (proB to preBII), and can be divided into fraction A-C (proB to preBI, upper rectangle) and fraction D (preBII, lower rectangle) by the expression of CD43. …”

Data Base COVID proyect by Carolina Cubillos Zapata (15345850)

“…<p> COVID-19 has emerged as a devastating disease in the last 2 years. Many authors appointed to the importance of kallikrein-kinin system (KKS) in COVID-19 pathophysiology as it is involved in inflammation, vascular homeostasis, and coagulation. …”

Supplementary Material for: Nasonia Parasitic Wasps Escape from Haller's Rule by Diphasic, Partially Isometric Brain-Body Size Scaling and Selective Neuropil Adaptations by Groothuis J. (4531123)

“…Haller's rule states that brains scale allometrically with body size in all animals, meaning that relative brain size increases with decreasing body size. …”

Effects of 20(S)-Rg3 on Snail expression and E-cadherin promoter activity. by Ting Liu (45625)

“…<p>(A) SKOV3 cells were cultured in normal condition for 24 h, and then cultured in 21% O₂ (normoxia) or 1% O₂ (hypoxia) or 1% O₂ and 80 µg/ml 20(S)-Rg3 (hypoxia+20(S)-Rg3) for another 24 h. …”

Polyampholyte−Surfactant Film Tuning in Reverse Microemulsions by Mabya Fechner (1943278)

“…Additionally, the required amount of surfactant to establish a clear w/o microemulsion depends on the pH value, which means the hydrophobicity of the copolymers. …”

Pathogenicity testing and transcriptome analysis. by Brett Hale (16510142)

“…<p>(<b>a</b>) Disease development in Race 25- (top) and Race 1-treated (bottom) hypocotyls at seven days post-infection. …”

The <i>ENT2</i> knockout effects on CRC proliferation and survival. by Safaa M. Naes (22075434)

“…Data are presented as means ± SD and expressed as % relative to control cells. * indicates a significant difference between NTC vs. …”

HC11 cells increase Pthlh gene expression and activity via cAMP with increases in intracellular 5HT. by Celeste M. Sheftel (9557588)

“…</b> Monoamine oxidase-A (MAO-A) gene expression is significantly upregulated in 5HTP treatment. …”

Immunolocalization and Western blot analysis of liver GK. by Magdiel Salgado (553127)

“…Hypoglycemia (A–C), normoglycemia (D–F) and hyperglycemia (G–I). …”

Spreading Depression Sends Microglia on Lévy Flights by Yelena Y. Grinberg (223907)

“…If true, then targeting mechanisms that retard activity-dependent microglial Lévy flights may be a novel means to reduce susceptibility to migraine.…”

Physiotherapeutic approach and functional performance after breast cancer surgery by Mariana Tirolli Rett (4648900)

“…DASH score decreased significantly from 28.06 ± 16.1 to 15.71 ± 10.7 (p = 0.001) meaning an improvement in functional performance of UL. …”

Circadian and novelty-induced locomotion and spatial memory in <i>Eno2</i>-ΔGR/EGFP bigenic mice. by Nadège Sarrazin (257824)

“…(<b>D</b>) Spatial learning in <i>Eno2</i>-ΔGR/EGFP bigenic mice was tested in the Morris water maze test. Mice have to find a hidden platform using extra maze cues. Latency to reach the platform from variable start positions decreased over time similarly in mutants (n = 10) and control mice (n = 14). …”