Th2 cytokines and IgE were decreased in G-1-treated BALB/c mice compared to non-treated controls. by Masamichi Itoga (706167)

Inflammatory cell accumulation was significantly decreased in G-1-treated C57BL/6 mice compared to non-treated controls. by Masamichi Itoga (706167)

Discrimination of rippled-spectrum patterns in noise: A manifestation of compressive nonlinearity - Fig 6 by Olga N. Milekhina (812701)

Incorrect splicing of <i>ISCU</i> in myoblasts with decreased SRSF3 expression. by Denise F. R. Rawcliffe (3269835)

<i>Aspergillus flavus</i> mRNA expression (a) <i>aflD</i> and (c) <i>aflR</i> and phylogenetic analysis of (b) <i>aflD</i> and (d) <i>aflR</i> after exposure to 50 mg/mL of <i>U. e... by Martha Cebile Jobe (21175426)

Trends in annual incidence of colectomy for benign neoplasms, stratified by age group. by Sara Sakowitz (14076650)

“…<p>Incidence of colectomy for benign disease decreased significantly from 2012 to 2019 across (A) ages 18–49, 50–64, 65–79, and ≥80 years and (B) sex. …”

Net work vs phase of activation and lattice spacing. Top) We simulated work loops in the half sarcomere model at phases of activation of 0 to 0.95 in 0.05 increments, as well as over lattice spacings from 12 to 18 nm and plotted the new work for each condition. Bottom) We then simulated work loops over the same range, but with the stiffness of either the linear or torsional spring comprising the crossbridge head increased or decreased by 50% separately.... by Travis Carver Tune (21012349)

“…Bottom) We then simulated work loops over the same range, but with the stiffness of either the linear or torsional spring comprising the crossbridge head increased or decreased by 50% separately. …”

Twenty-two identified and replicated loci and their overlap with associations to metabolic traits and clinical phenotypes. by Johannes Raffler (793347)

“…<p>^a SNP with the strongest association to targeted metabolic traits (“lead SNP”)</p><p>^b SNP with the strongest association to non-targeted metabolic traits</p><p>^c manually added to the list of most plausible candidate genes derived by evidence-based selection</p><p>^d additional candidates match to other non-targeted traits that also associate with the lead SNP</p><p>^e results from GWAS (<i>P</i> < 5.0×10⁻⁸)</p><p>^f mutations determined in clinical studies</p><p>For each locus, we selected all variants that displayed genome-wide significant association signals to metabolic traits in the SHIP-0 cohort. …”

Adherence to treatment guideline recommendations for Parkinson’s disease in Japan: A longitudinal analysis of a nationwide medical claims database between 2008 and 2016 by Masahiko Suzuki (355352)

“…Combination therapy with L-dopa, non-ergot DA, and monoamine oxidase-B inhibitors was gradually increased at a later stage.…”

The number of Brn3a-expressing cells in retino-collicular co-cultures decreases between DIV4 and DIV12. by Sylvie Voyatzis (332702)

“…(B, C) The density of cells immunoreactive for Brn3a undergoes a reduction of ∼68% between DIV4 and DIV7, and a further decrease of ∼22% between DIV 7 and DIV12. …”

DataSheet1_Familial Hypercholesterolemia: Real-World Data of 1236 Patients Attending a Czech Lipid Clinic. A Retrospective Analysis of Experience in More than 50 years. Part I: Gen... by Veronika Todorovova (12157917)

“…Differences were also found in the effects of various APOE isoforms on lipid lowering. A significant decrease in lipid parameters was observed with the E2E2 isoform whereas a minimal decrease was seen with the E4E4 and E3E3 isoforms.…”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…Mutation of seven residues to A (I118A, L122A, F125A, Q126A, L232A, I235A, and L239A) markedly decreased the F3-induced inhibition of TASK-1 channels, consistent with the molecular modeling predictions. …”

Growth curves (A, strain AWRI R2 (A); B, strain BH8 (B); C, strain Freddo (F)) and accumulated fermentation system mass loss(D, strain A; E, strain B; F, strain F) of <i>S</i>. <i>... by Xiang-yu Sun (748032)

Increased expression of Fz5 receptor matched with a decrease in NeuN immunoreactivity at 16w. by Carlos González-Fernández (2794207)

Schematic representation of the effects of stepwise bromination of the benzene ring of benzotriazole (Bt), including interdependence of the molecular volume (A) and pK_a (B) of the products with their IC₅₀ for inhibition of protein kinase CK2α: (a) Green arrows follow sequential bromination of the central vicinal C(5)/C(6) atoms, leading to a moderate decrease of pK_a and a large decrease in IC₅₀; (b) Red arrows illustrate the lesser effects of bromination of the peripheral C(4)/C(7) atoms, resulting in a significant decrease of pK_a, with virtually no gain in inhibitory activity; (c) Black lines link products with the same number of bromine atoms, but substantially differing in pK_a and IC₅₀, culminating in the di- and tri-brominated derivatives with inhibitory activities comparable to that of TBBt. by Romualda Wąsik (119538)

Omicron pseudoviruses with oligomannose-type N-glycans are non-infectious. by Sabrina Lusvarghi (2329267)

NREM 1/f slopes calculated from Power Spectrum Densities (PSDs) have a robust nocturnal rhythm at low frequencies that are initially flattened during spontaneous oxycodone withdraw... by Michael Gulledge (20577135)

Cysteamine decreases TG2 and increases CFTR expression in CF. by Chandra L. Shrestha (4495837)

miR-135a regulates mRNA expression in ERRα-dependent and–independent manners. by Violaine Tribollet (237332)

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