Altered TRPV1 staining in spinal cord dorsal horn of diabetic mice by Reddy M Pabbidi (44094)

“…Representative pictures of TRPV1 and NeuN staining from a control (a, b, c), STZ-induced diabetic hyperalgesic (d, e, f)), hypoalgesic (g, h, i), and non-diabetic TRPV1 knock-out mice (j, k, l). …”

Data Sheet 1_Effect of different 1-methylcyclopropene formulations and dosing on the ripening profile of Tommy Atkins mango fruits.docx by Geoffrey Chomba (20688014)

“…Interaction of 1-MCP concentration, exposure time, and maturity stage delayed other ripening-related changes including a decrease in hue angle, firmness, and increase in TSS. …”

Data Sheet 2_Comparison with healthy controls: meta-analysis of changes in intestinal flora in Chinese patients with irritable bowel syndrome.zip by Hao Tu (16412994)

“…</p>Aim<p>To investigate differential characteristics of gut microbiota in Chinese patients with IBS compared to healthy controls (HC).</p>Methods<p>We conducted a comprehensive search in PubMed, Web of Science, Embase, and China National Knowledge Infrastructure (CNKI) databases from their inception to May 2025. …”

Data Sheet 1_Comparison with healthy controls: meta-analysis of changes in intestinal flora in Chinese patients with irritable bowel syndrome.zip by Hao Tu (16412994)

“…</p>Aim<p>To investigate differential characteristics of gut microbiota in Chinese patients with IBS compared to healthy controls (HC).</p>Methods<p>We conducted a comprehensive search in PubMed, Web of Science, Embase, and China National Knowledge Infrastructure (CNKI) databases from their inception to May 2025. …”

Temporal Trend in Young-Onset Type 2 Diabetes - the Macrovascular and Mortality Risk: Study of UK Primary Care Electronic Medical Records by Digsu N. Koye (8881108)

“…The incidence rates of ASCVD and ACM declined in people aged ≥50 years, but did not decrease in people <50 years. …”

Sulfur supply effects on production and mineral nutrition of Tanzania guinea grass under barium levels in nutrient solution by Arnon Afonso de Souza Cardoso (9980536)

“…The combinations with high S and Ba levels resulted in a decrease of 1.7-fold in leaf area compared to combinations with high S without Ba. …”

DataSheet2_Exploring pyrrolidinyl-spirooxindole natural products as promising platforms for the synthesis of novel spirooxindoles as EGFR/CDK2 inhibitors for halting breast cancer... by Mohamed S. Nafie (9754305)

“…Conversely, compounds 5a-f displayed promising cytotoxicity against MCF-7 cells with IC₅₀ values range (IC₅₀ = 5.87–18.5 μM) with selective activity against MDA-MB-231 cancer cells. …”

DataSheet1_Exploring pyrrolidinyl-spirooxindole natural products as promising platforms for the synthesis of novel spirooxindoles as EGFR/CDK2 inhibitors for halting breast cancer... by Mohamed S. Nafie (9754305)

“…Conversely, compounds 5a-f displayed promising cytotoxicity against MCF-7 cells with IC₅₀ values range (IC₅₀ = 5.87–18.5 μM) with selective activity against MDA-MB-231 cancer cells. …”

High Efficacy but Low Potency of δ-Opioid Receptor-G Protein Coupling in Brij-58-Treated, Low-Density Plasma Membrane Fragments by Lenka Roubalova (784541)

“…Characterization of the direct effect of Brij-58 on the hydrophobic interior of isolated plasma membranes by steady-state anisotropy of diphenylhexatriene (DPH) fluorescence indicated a marked increase of membrane fluidity. The time-resolved analysis of decay of DPH fluorescence by the “wobble in cone” model of DPH motion in the membrane indicated that the exposure to the increasing concentrations of Brij-58 led to a decreased order and higher motional freedom of the dye.…”

BTK Expression Levels Control DNA Binding Activity and Transcription Factor Function of Ikaros. by Hong Ma (48973)

“…Each siRNA was used at a 50 nM concentration. BTK siRNA (but not Ku80 siRNA) resulted in depletion of BTK protein without a decrease in the amount of IK protein. …”

The Letters of Pope Gregory VII - pilot project by Tom Stafford (2768440)

“…It could be suggested that though Gregory’s output really did decrease, rather than being purely a result of disorganisation, Gregory was simply trying to get more done in fewer letters.…”

Image 1_Markers of immunosenescence in CMV seropositive healthy elderly adults.tif by Ivón Johanna Rodríguez (20601272)

“…Immunosenescence predisposes elderly individuals to a higher incidence of infectious and chronic non-communicable diseases with higher mortality rates. …”

Heat treatment of Hexa-Methylene Diamine Tetra-Methylene Phosphonic Acid (HMDTMPA) coating on biodegradable Mg to improve corrosion resistance and bioactivity by Hanaa Soliman (10518975)

“…The heat-treated films at 150°C showed remarkable anticorrosion performance about five times the non-heated film. In addition, bioactivity character such as live cells attraction was noticed due to the increase of P–O groups that compensated the decrease of O–H groups in the film structure. …”

BNIP3 regulates AT101-induced cytotoxicity in MPNST cells. by Niroop Kaza (563598)

“…T265-2c cells transfected with siRNA against <i>BNIP3</i> showed a significant decrease in BNIP3 protein levels (relative ratio to GAPDH) after treatment with AT101 (E) and were significantly protected from AT101-induced cell death (F), relative to cells transfected with non-target siRNA. …”

SSVEP phase delay preceding un-cued gaze shifts. by Sarah Enos Watamura (283322)

“…<p>Mean phase delay of SSVEPs elicited by the fixated (F, red curve) and non-fixated (NF, black curve) stimulus sequences in a 250 ms moving window during the 4 s preceding un-cued gaze shifts in the first (A), second (B), and third (C) shift sets. …”

MEIS1 is essential for <i>Krt19</i> transcription <i>in vitro</i> and is expressed in pancreatic ducts <i>in vivo</i>. by Johannes von Burstin (243524)

“…Genetic silencing of <i>Meis1</i> was efficient and resulted in a significant decrease of <i>Krt19</i> mRNA expression. …”

Effect of IFX on lymphocyte counts and cell activation. by Angela Sena (469304)

“…Values are expressed as mean ± SEM of percentage of cell percentages. (A) A significant increase in IBD patients in CD4+ T cells compared to IBD negative healthy controls with a significant decrease in patients initiating IFX therapy was observed. …”

DataSheet1_Late domain dependent E-cadherin recruitment into extracellular vesicles.PDF by Sebastian Bänfer (11719425)

“…Mutation of this motif results in a loss of interaction and a dramatic decrease in exosomal E-cadherin secretion. …”

Figure1 by Marco Niello (11112339)

“…</b>a) Saturation of DA uptake conducted in presence of cocaine 250nM (light grey), 500nM (grey) or 1000nM (dark grey). b) Cocaine increases Km in dose-dependent manner but c) does not decrease Vmax. d) <a>Saturation of DA uptake conducted in presence of S-αPVP 5nM (turquoise), 10nM (light blue) or 20nM (dark blue). e) αPVP does not drastically change the km, but f) reduces Vmax dose-dependently. …”

RAGE blocking and APP inhibition synergistically reduce oxidative stress, apoptosis and rescue sequential gliocentric cell fate change in DS HNPs. by Jie Lu (139953)

“…(B) Graphs show the S100B stimulation for 24 hours dose dependently increase H₂O₂ production and decrease mitochondrial membrane potential which can be blocked by RAGE antibody (1 µg/ml) or dalteparin sodium (1 IU/ml) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022126#pone.0022126.s005" target="_blank">Figure S5A</a></b>). …”