Dose response analysis of active compounds identified in the primary HTS. by Kishore Polireddy (153876)

“…<p>(a) ABCB6 expressing cells showed dose dependent decrease in median channel fluorescence (representing PPIX fluorescence) in response to benzethonium chloride, verteporfin, and to a lesser extent piperlongumine. …”

Synaptic facilitation between tail SNs and MNs following sensitizing tail shocks declined during aging. by Andrew T. Kempsell (738294)

“…C) Monosynaptic facilitation between tail SNs and MNs following sensitizing tail shocks decreased during aging. A single AP evoked in tail SNs by 50 ms injected current resulted in a monosynaptic EPSP in tail MNs in mature (n = 14) and aged II (n = 13) preparations. …”

Secondary screening of primary hits reveals four true <i>p27^Kip1</i> inhibitors. by Brandon J. Walters (301187)

“…Dose-dependent luciferase inhibition (black) and alamar blue inhibition (blue) of each compound (n = 3, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091173#pone-0091173-t001" target="_blank">Table 1</a> lists the calculated IC₅₀’s). …”

The public health system and the place of autism by Vanini Mandaj (16029441)

“…Final Considerations: although the Psychosocial Care Network for Children is the reference in the region, it is known that this facility alone cannot meet all needs of individuals with autism spectrum disorder. A service network coordinated according to patient’s individual needs and the region's reality would ensure their expected rights, decrease public spending, and enable these users to occupy not only one but many places in society.…”

Ndk contributes to phagosome maturation arrest. by Jim Sun (367834)

“…In the bottom panel dotted circles indicate the position of Ndk-beads, while the red fluorescent signal (PKH) shows the location of BSA-beads and a significant decrease of dextran colocalization with distant PKH-BSA-beads. …”

Intracellular chloride measurements by Wallace B Thoreson (5462)

“…An example of the reduction in MEQ fluorescence, indicating an increase in intracellular [Cl], produced by application of 12.1 mM Kto a cone. C. A greater decrease in MEQ fluorescence was produced by application of 69.9 mM K. …”

The effect of loss of combinations of PAPs on the phenotype of <i>Salmonella</i>. by Helen E. McNeil (8190873)

“…Data presented is the time taken for the fluorescence to decrease by 25% +/- SE. (Data for 10% and 50% drop can be seen in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008101#ppat.1008101.s011" target="_blank">S1 Table</a>) <b>B</b>. …”

Correlational learning rule for regulation of vestibular synapse strength by cerebellar inhibition: transfer of VOR gain from cerebellar cortex to brainstem. by John R. W. Menzies (361198)

“…During training the cerebellum has learnt to produce an inhibitory input modulated in phase with the vestibular input, leading to cancellation which produces a 50% gain decrease (since and , a weight requires ). …”

Substrate binding specificity of purified OpuAC. by Justina C. Wolters (207763)

“…The inhibition experiments with proline and carnitine show a decrease in the ΔF_max at increased concentrations of inhibitor, which is caused by the high concentrations of inhibitor (see panel A and B). …”

Loss of layer V pyramidal neurons of motor cortex. by Paolo d’Errico (494029)

“…Values are expressed as mean ± SEM. Scale bars: 5 mm in A; 50 µm in C.</p>…”

The adhesion genes are activated by TAp63β but not by ΔNp63β in Caski cells. by Youcef Ben Khalifa (203743)

“…<p>(A) Real-time PCR performed in Caski cells infected with recombinant adenoviruses expressing GFP compared to TAp63β (upper panel) or ΔNp63β (lower panel) at increasing m.o.i. (20, 50 and 100). …”

The capacity to neutralize free viruses prior to completion of CD4 attachment varies across bnAb classes. by Lucia Reh (546554)

“…R and p values are depicted. n.s. indicates a non-significant correlation. Direct correlation is denoted in blue, inverse correlation in orange.…”

Citrullinated proteins are present in the lactating mammary gland and are citrullinated, in part, by PAD3. by Guangyuan Li (6490)

“…Mouse mammary tissue from lactation day 2 (a, b, c), and day 9 (d, e, f) was harvested, fixed in 10% neutral buffered formalin, embedded in paraffin and sectioned. 5 μm mammary tissue sections were subject to a standard IHC protocol using a rabbit anti-citrulline antibody or an equal amount of non-specific rabbit IgG as a control. …”

Coexistence of distal oligodendrogliopathy in active NMO lesions in case NMO-4 by Katsuhisa Masaki (119851)

“…Immunostaining of Nogo-A is markedly decreased and apoptotic nuclear condensation of oligodendrocytes is present (I, insert). …”

Dataset_Jianping Sun_Ambient climate exceeds the effects of warming and precipitation treatment on leaf senescence phenology of community in an alpine meadow by Jianping Sun (21569150)

“…In this study, we conducted a 7-year (2015-2021) field manipulative experiment (including warming (+2 ºC) using infrared heater, decreased precipitation (-50%), increased precipitation (+100% in 2015 and +50% in 2016-2021) and their interactions) on the Qinghai-Xizang Plateau to investigate how warming, precipitation alterations, and ambient climate jointly influence LSP in an alpine meadow.…”

Image_1_QTL mapping and transcriptome analysis of sugar content during fruit ripening of Pyrus pyrifolia.png by Shuang Jiang (1443706)

“…In sweet cultivars, sucrose and fructose accumulate substantially, and sorbitol content decreases significantly during fruit ripening. A transcriptome analysis identified 125 upregulated and 222 downregulated differentially expressed genes (DEGs) in sweet cultivars. …”

Image_2_QTL mapping and transcriptome analysis of sugar content during fruit ripening of Pyrus pyrifolia.png by Shuang Jiang (1443706)

“…In sweet cultivars, sucrose and fructose accumulate substantially, and sorbitol content decreases significantly during fruit ripening. A transcriptome analysis identified 125 upregulated and 222 downregulated differentially expressed genes (DEGs) in sweet cultivars. …”

Image_3_QTL mapping and transcriptome analysis of sugar content during fruit ripening of Pyrus pyrifolia.tif by Shuang Jiang (1443706)

“…In sweet cultivars, sucrose and fructose accumulate substantially, and sorbitol content decreases significantly during fruit ripening. A transcriptome analysis identified 125 upregulated and 222 downregulated differentially expressed genes (DEGs) in sweet cultivars. …”

Mannitol uptake is repressed in vitro, but mannitol reaches <i>S</i>Tm inside host cells without affecting the host or bacterial metabolism. by Karin Mitosch (16851651)

“…(C) In vitro growth curves of wt, ∆<i>mtlA</i>, and ∆<i>mtlD</i> under repressive and non-repressive conditions, in MOPS medium with different carbon sources (combinations of glc, mtl, glycerol (glyc), and glc6P). …”

Relationship between change in OHI score and rank. by Benjamin S. Halpern (180356)

“…Blue points indicate regions that had a decrease in score but an increase in rank (N = 12); and red points indicate an increase in score and decrease in rank (N = 4).…”