DataSheet_1_Tuning Scorpion Toxin Selectivity: Switching From KV1.1 to KV1.3.docx by Andrei M. Gigolaev (9090713)

“…Despite several decades of research the molecular determinants of KTx selectivity are still poorly understood. Here we analyze MeKTx13-3 (Kalium ID: α-KTx 3.19) from the lesser Asian scorpion Mesobuthus eupeus, a high-affinity K_V1.1 blocker (IC₅₀ ~2 nM); it also affects K_V1.2 (IC₅₀ ~100 nM), 1.3 (~10 nM) and 1.6 (~60 nM). …”

Small dams also change the benthic macroinvertebrates community in rocky rivers by Leticia de Mattos (4618003)

“…In the dam site (2) there was a richness decrease. Non metric multidimensional analysis showed a clear spatial separation of large groups of macroinvertebrates and chironomid genera between sampling sites, indicating that there are typical taxa of each spatial compartment. …”

Hierarchical organization of conformational sub-states in ubiquitin motions. by Arvind Ramanathan (198127)

“…While in Level 1 the motions are global - involving the entire protein, Levels 2, 3 and 4 show subsequent localization of motions, as evidenced by their relative decrease in amplitude. The motions in each level involve well defined transitions from a relatively heterogenous population to a energetically homogenous sub-state. …”

Surgical Site Infection after Cesarean Delivery in Times of COVID-19 by Vicente Sperb Antonello (5312150)

“…A decrease of 49% in SSI was detected, with a median of 1.74 in the pre-COVID period and of 0.89 in the post-COVID period. …”

Data_Sheet_1_Aeroallergens and Climate Change in Tulsa, Oklahoma: Long-Term Trends in the South Central United States.docx by Estelle Levetin (3821509)

“…There was a non-significant trend toward increasing total pollen and a significant increase in tree pollen over time. …”

Table_1_Effects of dietary astaxanthin on growth performance, immunity, and tissue composition in largemouth bass, Micropterus salmoides.docx by Jiankun Zhang (1799080)

“…The astaxanthin supplementation increased the expression of the NF-E2-related factor (Nrf2) gene and reduced malondialdehyde (MDA) content and the expression of apoptosis genes Caspase-9 and Caspase-3 (P < 0.05), indicating that it has a good antioxidant ability. Furthermore, adding astaxanthin increased the content of non-specific immune markers and decreased the expression levels of the inflammatory factors interleukin-15 (IL-15) and tumor necrosis factor-α (TNF-α). …”

Environmental risk caused by drug waste in the city of Rio de Janeiro, Brazil, during the SARS-Cov19 pandemic by Carla Patricia Figueiredo Antunes de Souza (14728482)

“…The risk quotient (RQ) corresponded to the ratio between the estimated predictive environmental concentration (PECest) obtained by the consumption and excretion of each drug and its non-effective predictive concentration (PNEC). Between 2019 and 2020, the PECest of azithromycin (AZI) and ivermectin (IVE) increased between 2019 and 2020, with a decrease in 2021 probably due to shortages. …”

Table1_FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis.docx by Anuntxi Monsalve (13945395)

“…Mechanistically, FOXO1 inhibition in HE cells led to an increase in the non-oxidative branch of the PPP. During developmental erythropoiesis, the gradual decrease in FOXO1 activates the PPP and fuels nucleotide biosynthesis and cell proliferation.…”

Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration by Alicia N Vagnozzi (825979)

“…Furthermore, we speculate that extrinsic, non-genetic factors such as spatial constraint, distance from the wound, and basal versus suprabasal position may largely determine whether a cell ultimately persists.…”

The data underlying the graphs shown in Figs 1–5. by Fukuaki L. Kinoshita (21533193)

“…The synaptic homeostasis hypothesis (SHY) suggests synaptic depression during non-rapid eye movement (NREM) sleep, while other studies report synaptic potentiation or synaptic changes during NREM sleep depending on activities in wakefulness. …”

Seasonal variation of the photoacclimation state: Y(NPQ). by Cláudia Bártolo (17060956)

“…<p>Hysteresis light curves of the non-photochemical index Y(NPQ) of samples dominated by epipelic (VA-EPL) (A, C, E, G) and epipsammic (GE-EPM) (B, D, F, H). …”

Inhibition of human nSMase2 by cambinol and closely related analogs. by Mariana Figuera-Losada (744786)

“…<p><b>(A)</b> Cambinol (compound 1) structure. <b>(B)</b> Dose response curve for inhibition of human nSMase2 by increasing concentrations of cambinol ([¹⁴C]-SM assay). …”

Differences in magnitude and velocity of decay of the different compartments of the viral reservoir. by Maria C. Puertas (8801768)

“…<p>A. The overall decrease in each fraction of the viral reservoir during the first year after ART initiation is expressed as the ratio of week 48 to baseline values. …”

Clinical outcome according to neck lymph node SUV change after cycle 1 of IC. by Ulisses Ribaldo Nicolau (825606)

“…Patients with tumors demonstrating no change or decrease in neck lymph node SUV (neck lymph node SUV change (%) ≤ 0) were considered responders (N = 40; red) and those with tumors showing an increase in neck uptake (Neck Lymph Node SUV Change (%) > 0) were considered non-responders (N = 7; black).…”

Study design overview. by Juan J. Toscano-Angulo (21238347)

“…Computed tomography, micro-computed tomography and chemical composition analyses were conducted on different bone tissues (cortical, trabecular and woven) at several skeletal locations (the operated metatarsus, the contralateral one and the iliac crest) to assess the individual bone quality changes relative to the non-osteoporotic time point.</p><p>Results</p><p>After osteoporosis induction, the trabecular tissue experienced a 6.4% reduction in the bone mineral density, while no significant changes were reported in cortical tissue quality. …”

Information Sampling (Beads) Task and examples of agent performance in high and low certainty environments. by Diana C. Burk (14522613)

“…The plot also shows the corresponding action values for drawing a bead for the non-impulsive agent (black) and the impulsive agent (red). …”

Ellagic Acid Derivatives from <em>Terminalia chebula</em> Retz. Downregulate the Expression of Quorum Sensing Genes to Attenuate <em>Pseudomonas aeruginosa</em> PAO1 Virulence by Sajal Sarabhai (104656)

“…<em>C. elegans</em> fed on F7-treated <em>P. aeruginosa</em> showed enhanced survival with LT50 increasing from 24 to 72 h. LC-ESI-MS of F7 revealed the presence of ellagic acid derivatives responsible for anti QS activity in <em>T. chebula</em> extract.…”

Regulation of <i>sup-35</i>and <i>pha-1</i> by UBC-18–ARI-1. by Kumaran Mani (262977)

“…<p>(A) Testable model for the regulation of SUP-35 and PHA-1 by UBC-18–ARI-1. …”

Comparison of different classifiers with varying amounts of missing data. by Mallory Sheth (6477662)

“…We see that N-UFA is robust to missing data, with accuracy decreasing just 1.3% as the amount of missing data increases to 50%. …”

Impaired osteoclastogenesis in Cx43cKO fractures. by Alayna E. Loiselle (151690)

“…Cx43cKO fractures have significantly decreased Osteoclast number and Osteoclast surface at 28 days relative to WT. (*) indicates p<0.05 between groups at a given time-point, n=4 specimens/genotype/ time-point. …”