Lysine Residue at Position 22 of the AID Protein Regulates Its Class Switch Activity by Roland Geisberger (182277)

“…In order to regulate its specific activity and as a means to keep off-target mutations low, several mechanisms have evolved, including binding to specific cofactors, phosphorylation and destabilization of nuclear AID protein. …”

Bioenergetics of wildtype and <i>ATP6¹</i> animals. by Alicia M. Celotto (203614)

“…C) Comparison of uM AMP per mg of tissue between wildtype and <i>ATP6¹</i> animals show a modest decrease in AMP in aged mutants at day 20. …”

Understanding Hospitalization in Patients with Heart Failure by Evandro Tinoco Mesquita (4658629)

“…Patients admitted with heart failure have a high event rate (> 50%) with a mortality rate between 10 and 15% and a rehospitalization rate within 6 months after discharge of 30 to 40%. …”

TRAP staining: Osteoclasts formation in different groups. by Heng Yang (590400)

“…(AB = alveolar bone, PDL = periodontal ligament, R = tooth root, black arrow = TRAP-positive osteoclasts) (TRAP staining, scale bar, 50 µm). (E) Quantitative analysis of TRAP-positive osteoclasts (nuclei≥3) showed a significantly decreased number of osteoclasts in iPSC-MSCs and iPSC-MSCs/TSG-6 treated group, compared to untreated periodontitis group; the decrease number of osteoclasts showed a significant differences between iPSC-MSCs/TSG-6 and iPSC-MSCs treated group.…”

Metabolomic Response of <i>Calotropis procera</i> Growing in the Desert to Changes in Water Availability by Ahmed Ramadan (508121)

“…</p><p>We describe the results of studying the metabolomic response of wild <i>C procera</i> plants growing in the desert to a one time water supply. Leaves of <i>C. procera</i> plants were taken at three time points before and 1 hour, 6 hours and 12 hours after watering and subjected to a metabolomics and lipidomics analysis. …”

DataSheet_1_Growth and fatty acid distribution over lipid classes in Nannochloropsis oceanica acclimated to different temperatures.docx by Narcís Ferrer-Ledo (14596664)

“…Acclimation to low temperatures triggered a decrease in absorption cross section and photosynthesis rates with a tipping point at 17°C. …”

Acute Toxicity of Silver Free and Encapsulated in Nanosized Zeolite for Eukaryotic Cells by Clément Anfray (3923939)

“…Cells were exposed to silver-containing zeolites (50, 100, and 400 μg/mL) for 24 and 48 h. After exposure to Ag⁺-EMT (50 μg/mL) for 24 h, a loss in cell viability independent of the cell type was observed, ranging from −34.37 ± 23.90% for astrocytes to −99.5 ± 0.24% for U87-MG cells. …”

Shedding Light on the Stability and Structure–Property Relationships of Two-Dimensional Hybrid Lead Bromide Perovskites by Eugenia S. Vasileiadou (10091493)

The effect of 4 day’s starvation on visible protein aggregates. by Ulfat I. Baig (233369)

“…Means calculated excluding (A) and including (B) aggregate free cells. …”

miR-135b negatively regulates the hMSC osteogenic differentiation. by Song Xu (187853)

“…<p>(A) ND-hMSCs are transfected with miR-135b mimic (50nM), miRNA mimic negative control (miR-C) (50nM) or transfection reagent only (Mock) within OM for 3 days. …”

Similarity diagrams for the evaluation of M1, M2 and ANN precision. by Thomas Schmid (428873)

“…Plotting these differences on the three axes of a three-dimensional coordinate system yielded a distribution with all data points falling onto a single plane within the three-dimensional space. …”

MLN4924 regulates NSs-dependent early PKR activation in RVFV-infected cells. by Rajini Mudhasani (619683)

“…The data derived from MLN4924 treated cells was normalized with the corresponding DMSO treated controls (average infection rates are indicated under the bar graph), which were considered as 100% and expressed as the mean ± SD. The inset shows a decrease in PKR expression levels in PKR siRNA transfected cells by Western blot analysis. …”

Table_1_Chemotherapy effect on myocardial fibrosis markers in patients with gynecologic cancer and low cardiovascular risk.pdf by Lu Ye (1978777)

“…The number of chemotherapy cycles was associated with an increase in the ECV (Standard regression coefficient [β] = 0.383, P = 0.014) and a decrease in the ICMi (β = -0.349, P = 0.009).…”

Comparison of observed and simulated foraging rates. by Balaji Prabhakar (310460)

“…<p>The rate of returning foragers was experimentally decreased by removing the returning foragers, leading to a decrease in the rate at which outgoing foragers left the nest. …”

Clinical and sputum characteristics of patients categorized according to GINA. by Gautam Damera (59984)

“…<p>GINA: Global Initiative for Asthma; BD: bronchodilator; LABA: long-acting bronchodilator; FEV₁: forced expiratory volume in one second; TCC: total cell counts; BDP: beclomethasone dipropionate; PC₂₀FEV₁: provocative concentration of methacholine to induce a 20% decrease in FEV1;</p><p>*mean (SE);</p>†<p>geometric mean (95% CI);</p>‡<p>median (IQR);</p><p>**<i>P</i><0.05 compared to control.…”

The ratio between fluctuactions in the OFF and ON states is mantained at larger volumes. by David Frigola (332063)

“…Relative fluctuations have been computed as the ratio between the standard deviation over the mean steady state. Standard deviations and mean values have been extracted from Langevin dynamics as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031407#pone-0031407-g002" target="_blank">Fig. 2</a>. …”

Incremental contribution from adding components to three prevention packages. by Ron Brookmeyer (212255)

“…<p>Table presents percent infections prevented from adding a component with 95% confidence intervals (CI). …”

Effect of aging on the scotopic ERG and its daily rhythm. by Kenkichi Baba (322085)

“…<p>The amplitude of the a wave (A–C) and b wave (D–F) of the scotopic ERG steadily decreased during aging, and the daily rhythm in the a and b wave amplitude was only present in mice at 3 and 6 months (Two-way ANOVA, P<0.001, followed by Tukey tests). …”

Change in percentage of pO values ≤5 mmHg by Bernardino Clavo (3925)

“…</p> During ozone therapy, a decrease in percentage of pO values ≤5 mmHg at each measurement time-point was observed in the tumors of patients: = before ozone therapy; = after session #1 ( = 0.002); = 48 h after session #2 ( = 0.045); = after session #3 ( = 0.033). …”

Skin infection in the humanized mouse at 7 d post-inoculation. by Sergio Lizano (269986)

“…Each data point represents an inoculated skin graft. Bacterial inoculums are indicated as wt Alab49 (upper panel) and Alab49 <i>rofA::aad9</i> (lower panel). …”