Caspase 3 and CD62L expression is progressively lost as proliferation proceeds. by Scott McComb (234597)

“…(B) OVA specific CD8⁺ T cells were gated for division number based on CFSE dilution. Cells show a significant, coordinate decrease in the expression of active caspase-3 and CD62L/IL7Rα as cell proliferation proceeds (***P<0.005, *P<0.05, n = 3 per timepoint).…”

Data_Sheet_6_DNA Methylation Is Responsive to the Environment and Regulates the Expression of Biosynthetic Gene Clusters, Metabolite Production, and Virulence in Fusarium graminear... by Christopher Bonner (9990611)

“…In this study, we characterized two DNMTs (FgDIM-2 and FgRID) in F. graminearum, with homologies to “Deficient in methylation” (DIM-2) and “Repeat-induced point (RIP) deficient” (RID) from Neurospora. The loss of DNMTs resulted in not only a decrease in average methylation density in the nutrient-poor, compared to nutrient-rich conditions, but also differences in the genes expressed between the WT and the DNMT mutant strains, implicating the external environment as an important trigger in altering DNA methylation patterns. …”

Time course of microglial/macrophages phagocytic activity after ischemia: effect of 3-AB treatment. by Alexandre Madinier (368860)

“…Note the absence of staining at 4 h in vehicle (A1–2) and 3-AB treated animals (B1-2). Rats treated with 3-AB (D1–2) showed a decrease in ED-1 staining at 24 h as compared to vehicle treated animals (C1–2). …”

Kinetic Characterization of the <i>in vitro</i> GST-E6/E6AP-BAP Binding Assay. by Jonathan J. Cherry (501180)

“…Dissociation was measured as a decrease in BAP signal at each time point. (<b>C</b>) The E6AP 18-mer peptide inhibits the interaction between E6AP-BAP and GST-16 E6. …”

Data_Sheet_1_DNA Methylation Is Responsive to the Environment and Regulates the Expression of Biosynthetic Gene Clusters, Metabolite Production, and Virulence in Fusarium graminear... by Christopher Bonner (9990611)

“…In this study, we characterized two DNMTs (FgDIM-2 and FgRID) in F. graminearum, with homologies to “Deficient in methylation” (DIM-2) and “Repeat-induced point (RIP) deficient” (RID) from Neurospora. The loss of DNMTs resulted in not only a decrease in average methylation density in the nutrient-poor, compared to nutrient-rich conditions, but also differences in the genes expressed between the WT and the DNMT mutant strains, implicating the external environment as an important trigger in altering DNA methylation patterns. …”

Data_Sheet_3_DNA Methylation Is Responsive to the Environment and Regulates the Expression of Biosynthetic Gene Clusters, Metabolite Production, and Virulence in Fusarium graminear... by Christopher Bonner (9990611)

“…In this study, we characterized two DNMTs (FgDIM-2 and FgRID) in F. graminearum, with homologies to “Deficient in methylation” (DIM-2) and “Repeat-induced point (RIP) deficient” (RID) from Neurospora. The loss of DNMTs resulted in not only a decrease in average methylation density in the nutrient-poor, compared to nutrient-rich conditions, but also differences in the genes expressed between the WT and the DNMT mutant strains, implicating the external environment as an important trigger in altering DNA methylation patterns. …”

The morphogenesis and development of VM dopaminergic neurons is disturbed in <i>Dkk1^{<b>−/−</b>}</i> embryos. by Diogo Ribeiro (230483)

“…(B) Immunohistochemistry for TH in midbrain sections of <i>Dkk1^−/−</i> embryos revealed a decrease of aberrantly distributed dopaminergic neurons (upper panels) or an almost absence of dopaminergic neurons (bottom panels). …”

Emodin suppresses HG-induced cFLIP generation but not repressing its activation and increasing degration. by Junjie Gao (545578)

“…<p>(<b>a, b</b>) MCs were cultured in HG media and treated with 50 μM emodin for indicated times. …”

Motion of FisB clusters is not coupled to cell wall synthesis, or pH and voltage gradients across the cell membrane. by The PLOS Biology Staff (11836235)

“…Colored lines connect averaged points, whereas gray areas represent standard deviation and error bars represent the standard error of the mean (SEM). …”

Difference and Equilibrium spectra and modelling of the putative R and M absorption spectra. by Ludovic S. Mure (262696)

“…The data point at 400 nm (gray circle) is from a single subject and thus was not included in the spectral response curve. …”

Self-organization of bacterial communities against environmental variations. by Sohei Tasaki (3808798)

“…The left center is the inoculation point. Initial nutrition level, 2.0 g l^-1 peptone (A-C). …”

Computed C3b opsonization per cell if factor H can be acquired on the cell surface of the pathogen. by Stefan N. Lang (787857)

“…Microbial cell densities for subfigures (I)-(V) can be seen from the corresponding points in the lower panel (see also text). The dotted vertical line in each subfigure represents the mean value of the optimal threshold interval to distinguish the two signals. …”

<i>Bax</i> Deficiency Prevents Glaucomatous RGC Death by Richard T Libby (33317)

“…<div><p>To determine the effects of BAX deficiency on RGC death in glaucoma, we analyzed RGC layer cells at stages with and without glaucomatous optic nerve damage (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0010004#s4" target="_blank">Materials and Methods</a>). …”

Assessment of Central Blood Pressure and Arterial Stiffness in Practicing Long-Distance Walking Race by Edison Nunes Pereira (4652905)

“…<div><p>Abstract Background: An ecological hiking occurs yearly in Brazil. It is a unique event because of its distance (310 km) and dynamics (mean of 62 km/day for 5 days with mean pace of 7.6 km/h). …”

Physiological risk of falls, physical and aerobic capacity in community-dwelling elderly by Lygia Paccini Lustosa (4650658)

“…Results: Participated 59 elderly (71.8±5.0 ys). The mean performance in PPA was 0.4±0.4; SPPB was 10.4±1.7 and ISWT was 281±111.7 meters. …”

Changes in the GRF, duty factor and mechanical energy fluctuations with increasing speed. by P. J. Bishop (4219759)

<i>N. meningitidis</i> infection of HBMEC causes degradation of occludin. by Alexandra Schubert-Unkmeir (154787)

“…A weak specific occludin fragment with an apparent molecular mass of 50–kDa is generated during infection at 24 h p.i. …”

Comparison between patients and volunteers for aortic distensibility at rest and exercising. by Paul Habert (6166844)

Histopathological alterations in the spleen and liver. by Sergio Cuervo-Escobar (678682)

Schema of CD4∶CD8 ratio in HIV infection. by Brinda Emu (231184)