5-FU nanoparticle had liver-targeting and enhanced 5-FU to inhibit the growth of hepatic caner through ASGPR <i>in vivo</i>. by Mingrong Cheng (302795)

“…<p>(A) Expression of ASGPR mRNA in different tissues of hepatic cancer, liver, spleen, kidney, lung, muscle, heart and bowel in the orthotropic liver cancer mouse model evaluated by RT-PCR. …”

Central <i>Dusp6</i> expression is not affected by changes in body composition or nutrition. by Katrin Pfuhlmann (4413625)

“…<p>Decreased body weight (A) and food intake (B) but unchanged levels of <i>Dusp6</i> mRNA in brain areas (C) of chow-fed Lep^ob mice treated daily for 6 days with 1 mg/kg of leptin (Leptin) and chow-fed Lep^ob mice treated with saline but pair-fed (Saline pf) to the Leptin group, compared to ad libitum fed saline controls (Saline <i>ad lib</i>) (n = 5–6 mice; food intake: n = 3 cages). …”

EA treatment restored <i>Stat</i>5NKO-induced obese phenotype, improved energy metabolism and cold tolerance in the <i>Stat</i>5NKO obese mice. by Shu-Ping Fu (549948)

“…<p>(A) Observation of body weight in the four groups, n = 10 in each group. …”

Image1_Dexmedetomidine Protects Against Septic Liver Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT1 Signaling Pathway.TIF by Qing Yu (337275)

“…</p><p>Conclusion: We demonstrated a novel mechanism in which DEX protects against CLP-induced liver injury. …”

GLP-1 fails to rescue apoptosis in ENPP1 transfected cells. by Nunzia Caporarello (221943)

“…<p>Apoptosis was assessed by caspase 3/7 activity, in INS-1E (panel A) and βTC-1 (panel B) cells, either transfected with neo or ENPP-1 gene variant. …”

Chondrocyte death in the knee joints of mice with immune-complex-mediated arthritis (ICA) by Karin CAM Nabbe (58865)

“…IL-13 significantly decreased chondrocyte death, both at day 3 and at day 7 (a). …”

The effect of rosiglitazone-treated stromal cells on myeloid differentiation in HSPCs. by Wenyi Lu (701872)

“…<p>(A) C3H10T1/2 cells and M2-10B4 were treated with 10 μM rosiglitazone in the presence or absence of BADGE(20μM). …”

Positional Isomeric Effects on the Optical Properties, Multivalent Glycosidase Inhibition Effect, and Hypoglycemic Effect of Perylene Bisimide–deoxynojirimycin Conjugates by Ren-Feng Li (10688392)

“…The molecular docking results showed that the active fragment of <b>PBI-4DNJ-1</b> has the highest binding energy (9.649 kcal/mol) and the highest total hydrogen bond energy (62.83 kJ/mol), which were related to the positional isomeric effect on the hypoglycemic effect in mice. This work introduced a new means to develop antihyperglycemic agents in the field of multivalent glycomimetics.…”

Glass Formation of Null-Matrix Cu-Hf-(Zr, Ti) Alloys by Octavio Lozada-Flores (8301582)

“…The results also showed that the parameters obtained from thermal analysis did not correlate with the GFA obtained. However, a good correlation of GFA and dc was found by means of the topological model, where the highest % packing efficiency (53.57 %) was found for the Cu61.48Hf18.52Zr6.48Ti13.52 alloy, which also showed the highest dc value with 6 mm.…”

Data_Sheet_1_Improvement of Mesenchymal Stem Cell Immunomodulatory Properties by Heat-Killed Propionibacterium acnes via TLR2.PDF by Gabriela da Paz Silveira (6194351)

“…As these cells share the same MSCs bone marrow (BM) site and interact with each other, here we evaluated the P. acnes and its soluble polysaccharide (PS) effect on MSCs and their immunomodulatory role in a murine model of traumatic brain injury (TBI). …”

BBSome proteins are required for surface expression of the IR. by Rachel D. Starks (759300)

“…<p><b>A</b>) Silencing the <i>Bbs1</i> or <i>Bbs2</i> genes using shRNA reduced IR surface expression in HEK293T cells. …”

Noninvasive Recognition and Biomarkers of Early Allergic Asthma in Cats Using Multivariate Statistical Analysis of NMR Spectra of Exhaled Breath Condensate by Yan G. Fulcher (1316178)

“…OSC-PLS-DA of the normalized spectra suggest the most promising biomarkers of allergic asthma in cats to include increased acetone, metabolite(s) with overlapped NMR peaks near 5.8 ppm, and a hydroxyphenyl-containing metabolite, as well as decreased phthalate. …”

Supplementary Information Files for 'Does hypohydration really impair endurance performance? Methodological considerations for interpreting hydration research' by Lewis James (1249500)

“…Second, most of the methods used to induce hypohydration are both uncomfortable and unfamiliar to the subjects, meaning that alterations in performance may be caused by this discomfort, rather than hypohydration per se. …”

Anti-apoptotic effect of <i>M</i>. <i>bovis</i>. by Qiao Pan (18611470)

“…<i>bovis</i> significantly decreased in EBL cells pretreated with STS. All assays were performed with three independent experiments, and values represent the means ± SDs. …”

Tyrphostin AG490 reduced chemokine secretion and cell cycle arrest. by Mojca Gasparitsch (8138415)

“…<p>Tyrphostin decreased CC-chemokine ligand 2 (CCL2) expression in stretched tubular PKSV-PR cells <b>(a)</b>. …”

<i>S</i>-sulfhydration enhances anti-oxidative stress responses. by Sau Ha Cheung (660961)

“…<p>(A) Immunofluorescence staining of GPx1 in aortic root of ApoE KO mice with or without H₂S treatment. …”

Data_Sheet_1_nifH Gene Sequencing Reveals the Effects of Successive Monoculture on the Soil Diazotrophic Microbial Community in Casuarina equisetifolia Plantations.docx by Liuting Zhou (7862426)

“…Taxonomic analysis showed that the phyla Proteobacteria increased while Verrucomicrobia decreased under the consecutive monoculture (SCP and TCP). …”

Effect of 500 bp C-terminal of TE deletion on virulence in the <i>F</i>. <i>monophora</i> infection mice model. by Minying Li (4477666)

“…<p>The conidia (1×10⁶) of all strains injected into the footpads of mice to infect mice. (A and B) The footpad thickness of mice were photographed and measured 3, 5, 7 and 14 days after infection. …”

DataSheet_1_Enhanced CT-Based Radiomics to Predict Micropapillary Pattern Within Lung Invasive Adenocarcinoma.pdf by Yunyu Xu (11340522)

“…Of these 121 were used as a training cohort and the other 49 as a test cohort. …”

Table1_Circulating erythroferrone has diagnostic utility for acute decompensated heart failure in patients presenting with acute or worsening dyspnea.docx by Sarah Appleby (15395237)