Covalent <i>Plasmodium falciparum</i>-selective proteasome inhibitors exhibit a low propensity for generating resistance <i>in vitro</i> and synergize with multiple antimalarial ag... by Barbara H. Stokes (5697422)

“…Selection studies reveal that parasites do not readily acquire resistance to WLL or WLW and that mutations in the β2, β5 or β6 subunits of the 20S proteasome core particle or in components of the 19S proteasome regulatory particle yield only Plasmodium proteasome that can select for resistant parasites with >hundred-fold decreases in susceptibility. …”

RNA Editome in Rhesus Macaque Shaped by Purifying Selection by Jia-Yu Chen (135555)

“…We verified 96.6% of editing sites in coding regions and 97.5% of randomly selected sites in non-coding regions, as well as the corresponding levels of editing by multiple independent means, demonstrating the feasibility of our experimental paradigm. …”

³¹P NMR spectroscopy indicates an energy deficit in 6-week-old <i>mdx</i> mice. by Christopher R. Heier (410734)

“…Note, peaks for inorganic phosphate were not detectable in several mice of both genotypes (3 <i>mdx</i> and 5 wild-type); values for these mice were uniformly omitted from the Pi analysis (Pi, inorganic phosphate; PCr, phosphocreatine; ATP, adenosine triphosphate; tATP, total ATP; n = 3–6 mice per data point; data are means ±SEM; *<i>p</i>≤0.05, ***<i>p</i>≤0.001).…”

Image_1_Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping.tif by Benjamin Jurek (322560)

“…Sensitive digital PCR (dPCR) provided us with the means to differentiate between wild type and truncated OXTR in our cellular model. …”

Is there a link between heart rate variability and cognitive decline? A cross-sectional study on patients with mild cognitive impairment and cognitively healthy controls by Bernhard Grässler (10699212)

“…Methods Cardiac autonomic control was assessed by means of heart rate variability (HRV) at resting state and during cognitive tasks in 22 older adults with MCI and 29 healthy controls (HCs). …”

Effects of shRNA mediated p53 inhibition on RITA response in HN30 and HN31 cells. by Hui-Ching Chuang (614643)

“…Quantitative data are expressed as means ± S.E from three experiments. In all cell lines (control and sh53), RITA treatment led to significantly (p<0.05) decreased colony formation at all doses tested. …”

Redd1 inhibits β-catenin action. by Qiang Feng (88137)

“…Representative view of <i>gfp</i> mRNA-, <i>β-catenin ΔN</i> mRNA-, and <i>β-catenin ΔN</i> mRNA <i>+ redd1</i> mRNA-injected embryos at 5 somite stage is shown in A). Scale bar = 200 µm. …”

Image_2_Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping.tif by Benjamin Jurek (322560)

“…Sensitive digital PCR (dPCR) provided us with the means to differentiate between wild type and truncated OXTR in our cellular model. …”

Triboelectric Nanogenerators Made of Porous Polyamide Nanofiber Mats and Polyimide Aerogel Film: Output Optimization and Performance in Circuits by Hao-Yang Mi (1583152)

“…With an optimum material thickness, a TENG with only a 2 cm² effective device size achieved a high output voltage of 115 V and a current of 9.5 μA under a small compressive pressure (30 kPa). …”

uORFs overlapping CDS mediate the highest repressive potential. by Philipp Fervers (5616980)

“…(<b>B</b>, <b>C</b>, <b>D</b>) The uORF’s repressive potential decreases with increasing uORF to CDS distance.</p>…”

Triboelectric Nanogenerators Made of Porous Polyamide Nanofiber Mats and Polyimide Aerogel Film: Output Optimization and Performance in Circuits by Hao-Yang Mi (1583152)

“…With an optimum material thickness, a TENG with only a 2 cm² effective device size achieved a high output voltage of 115 V and a current of 9.5 μA under a small compressive pressure (30 kPa). …”

Effects of cyclophilin inhibition and oxidant on mitochondrial sensitivity to permeability transition during a continuous calcium infusion. by Saori Morota (428715)

“…Samples were prepared before (incubation) and during calcium infusion (Ca²⁺ pre-mPT), after induction of respiratory inhibition (Ca²⁺ post-mPT) and following addition of the non-specific ionophore alamethicin. Values are means ± SD, n = 4–8 in panel C and n = 5 in panel D. …”

Triboelectric Nanogenerators Made of Porous Polyamide Nanofiber Mats and Polyimide Aerogel Film: Output Optimization and Performance in Circuits by Hao-Yang Mi (1583152)

“…With an optimum material thickness, a TENG with only a 2 cm² effective device size achieved a high output voltage of 115 V and a current of 9.5 μA under a small compressive pressure (30 kPa). …”

CARDIOVASCULAR EFFECTS OF 16 WEEKS OF MARTIAL ARTS TRAINING IN ADOLESCENTS by Bruna Thamyres Ciccotti Saraiva (10445634)

“…Physical activity is one of the means of prevention and treatment of these diseases, thus martial arts represent a dynamic option in promoting physical activity. …”

Gonococci invasion of human macrophages is independent of CEACAM1. by Stanimir S. Ivanov (3394922)

“…<p><b>(A)</b> qPCR mRNA analysis for <i>ceacam1</i>, <i>ceacam3</i>, <i>ceacam5</i> and <i>ceacam6</i> was carried out on U937 MFs that were either infected with <i>N</i>.…”

Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants. by Tobias Holm Bønnelykke (20968460)

“…(<b>F</b>) Brightfield images of wild type (f1), control <i>Notch3</i> heterozygote (f2) compared to homozygote <i>Nodal</i> mutants with decreased <i>Notch3</i> (f3) at E9.5, in a ventral view. …”

Lengthened ependymal cilia and increased ciliary beating function and frequency in the Katnal2-KO brain. by Ryeonghwa Kang (6793046)

“…(<i>n</i> = 60 beads from 4 mice [WT-AD], 39, 4 [WT-AV], 62, 4 [KO-AD], 33, 4 [KO-AV], 116, 4 [WT-PM], and 82, 4 [KO-PM], Student’s <i>t</i>-test [AV bead speed], Mann-Whitney test [AD bead speed, PM bead speed]). (H) A decreased speed of microbeads in AD + AV regions after a 10-min pretreatment of brain slices with pneumolysin (PNML; 0.5 μg/ml) (<i>n</i> = 40 beads from 3 mice for pneumolysin and control [without pneumolysin] groups, Mann–Whitney test). …”

Dopants Control Electron–Hole Recombination at Perovskite–TiO₂ Interfaces: <i>Ab Initio</i> Time-Domain Study by Run Long (1304349)

Image_1_miR-96 Inhibits SV2C to Promote Depression-Like Behavior and Memory Disorders in Mice.pdf by Lidong Sun (288628)

“…A depression-like behavior and memory disorder mouse model was initially established by means of intraperitoneal injection with lipopolysaccharide. …”

DataSheet_1_Murine macrophage-based iNos reporter reveals polarization and reprogramming in the context of breast cancer.docx by Javier A. Mas-Rosario (14651398)

“…Collectively, this work demonstrates that this reporter-based approach provides a facile means to study macrophage responses in complex, multicomponent environments. …”