IPSE exhibits dose-dependent heptotoxicity that is neutralized by specific monoclonal antibody. by Maha-Hamadien Abdulla (67713)

The effect of TP-10 treatment on motor behaviors. by Carmela Giampà (360711)

DataSheet_1_Stapled peptide PROTAC induced significantly greater anti-PD-L1 effects than inhibitor in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…</p>Results<p>In cervical cancer celllines C33A and HeLa, the stapled peptide strongly downregulated PD-L1 to < 50% of baseline level at 0.1 μM. …”

Anti-Cancer Effect of Thiacremonone through Down Regulation of Peroxiredoxin 6 by Miran Jo (533723)

“…Thus, we investigated whether thiacremonone inhibits cell growth by blocking glutathione peroxidase of PRDX6 in the human lung cancer cells, A549 and NCI-H460. Thiacremonone (0–50 μg/ml) inhibited lung cancer cell growth in a concentration dependent manner through induction of apoptotic cell death accompanied by induction of cleaved caspase-3, -8, -9, Bax, p21 and p53, but decrease of xIAP, cIAP and Bcl2 expression. …”

Hemodialysis-Related Glycemic Disarray Proven by Continuous Glucose Monitoring: Glycemic Markers and Hypoglycemia by Akinori Hayashi (305316)

“…</p> <p><b>RESULTS</b></p> <p>Sensor glucose level (SGL) showed a sustained decrease during HD, irrespective of the dialysate glucose concentration, and reached a nadir that was lower than the dialysate glucose concentration in 49 participants (50%). …”

SFTSV infection disrupts the endothelial cell barrier. by Shijie Xu (3324546)

“…The continuity and integrity of endothelial cells markedly decreased compared with negative control mice along with a higher incidence of red blood cell leakage around the disintegrated pulmonary vessel as shown by the red arrow. …”

Joule heating of the brain tissue during the application of pulsed electric fields for e-biopsy. by Ilai Genish (12569114)

“…Panels <b>a-c</b> show the simulation for high voltage, short-duration protocol: 40 pulses 1000 V, 40 μs, 4 Hz, coupled with the simulation for low voltage, long-duration protocol: 40 pulses 50 V, 15 ms, delivered at 4 Hz. …”

Insulin treatment does not alter expression of anti-inflammatory markers YM1 and CD206. by Fiona Brabazon (5687624)

“…<p>Quantitation of western blots for YM1 showed that LPS exposure significantly decreased expression, but insulin had no effect (n = 3/group, A). …”

TGF-β1 is required for NRP2-mediated EMT. by Camille Grandclement (215143)

“…Histone-H1 was used as a control of protein loading. Whereas only 10 µM of SB-431542 decreases the nuclear level of phosphorylated Smad2 in Colo320 cancer cells, doses of 50 µM should be used to decrease the nuclear level of phosphorylated Smad2 in HT29^NRP2 cancer cells. …”

Protective effect of L-carnitine on myocardial injury in rats with heatstroke by Xisong Wang (10394395)

“…Methods: orty-eight rats were randomly divided into control, heatstroke and 25, 50 and 100 mg/kg L-carnitine groups. The last three groups were treated with 25, 50 and 100 mg/kg L-carnitine, respectively, for seven successive days. …”

Markers of inflammation in 10-day old implants from non-diabetic and diabetic rats. by Teresa Oviedo Socarrás (654955)

“…An increase in MPO activity (A) and decreased in NAG activity (B) were observed after diabetes induction, indicating a persistence of acute inflammatory response and delay in the chronic response. …”

Expression profiles of genes whose mRNA levels were up- or down-regulated in the PBMCs of 15 IgAN (IgAN1- IgAN15) and eight MN (MN1-MN8) patients relative to those of HVs. by Yasuyuki Nagasawa (515930)

“…<p><b>(A)</b> List of the top 50 genes up-regulated in most IgAN and MN patients, shown in decreasing order of fold-change values. …”

Artery Wall Assessment Helps Predict Kidney Transplant Outcome by Domingo Hernández (4919257)

“…This could lead to a higher post-transplant mortality. Pre-transplant c IMT, post-transplant diabetes and triglycerides at 1-year post-transplantation may condition a high c-IMT measurement post-transplantation, which may decrease patient survival.…”

DataSheet_1_Case Report: Molecular and microenvironment change upon midostaurin treatment in mast cell leukemia at single-cell level.pdf by Meng-Ke Liu (10306315)

“…With poor response to conventional poly-chemotherapy, mast cell leukemia responded to the midostaurin treatment with a 50% overall response rate (ORR), but complete remission rate is approximately 0%. …”

DataSheet_2_Case Report: Molecular and microenvironment change upon midostaurin treatment in mast cell leukemia at single-cell level.pdf by Meng-Ke Liu (10306315)

“…With poor response to conventional poly-chemotherapy, mast cell leukemia responded to the midostaurin treatment with a 50% overall response rate (ORR), but complete remission rate is approximately 0%. …”

DataSheet_4_Case Report: Molecular and microenvironment change upon midostaurin treatment in mast cell leukemia at single-cell level.docx by Meng-Ke Liu (10306315)

“…With poor response to conventional poly-chemotherapy, mast cell leukemia responded to the midostaurin treatment with a 50% overall response rate (ORR), but complete remission rate is approximately 0%. …”

Expression of oligodendroglial markers by OL-like cells. by Cristiana Leite (651863)

“…<p>The expression of the OPC marker A2B5 (<i>A-D</i>), the OPC/OL marker O4 (<i>E-H</i>) and the OL markers GalC (<i>I-L</i>) and MBP (<i>M-P</i>) in OL-like cells derived from OPC-like cells cultured on fibronectin was determined by immunofluorescence microscopy. …”

DataSheet_3_Case Report: Molecular and microenvironment change upon midostaurin treatment in mast cell leukemia at single-cell level.docx by Meng-Ke Liu (10306315)

“…With poor response to conventional poly-chemotherapy, mast cell leukemia responded to the midostaurin treatment with a 50% overall response rate (ORR), but complete remission rate is approximately 0%. …”

Image2_Evaluating the inhibitory effect of resveratrol on the multiplication of several Babesia species and Theileria equi on in vitro cultures, and Babesia microti in mice.pdf by Shimaa Abd El-Salam El-Sayed (13834724)

“…Reverse transcription PCR assay showed that such inhibitory activity might be attributed to resveratrol’s stimulatory effect on B. bovis KDAC3 (BbKADC3) as well as its inhibitory effect on BbKATS. RVT causes a significant decrease (P < 0.05) in cardiac troponin T (cTnT) levels in heart tissue of B. microti- infected mice, thereby indicating that RVT may play a part in reducing the cardiotoxic effects of AZM. …”

Table1_Evaluating the inhibitory effect of resveratrol on the multiplication of several Babesia species and Theileria equi on in vitro cultures, and Babesia microti in mice.pdf by Shimaa Abd El-Salam El-Sayed (13834724)

“…Reverse transcription PCR assay showed that such inhibitory activity might be attributed to resveratrol’s stimulatory effect on B. bovis KDAC3 (BbKADC3) as well as its inhibitory effect on BbKATS. RVT causes a significant decrease (P < 0.05) in cardiac troponin T (cTnT) levels in heart tissue of B. microti- infected mice, thereby indicating that RVT may play a part in reducing the cardiotoxic effects of AZM. …”