Analyzing the clinical benefit of newer therapies for advanced or metastatic non-small-cell lung cancer: application of the ESMO-magnitude of clinical benefit scale v1.1 by Ricardo García-Fumero (11042247)

“…</p> <p>ESMO-MCBS scores were calculated for 42 positive clinical trials. 54.8% met the ESMO-MCBS thresholds for clinically meaningful benefit (final grade of 4 or 5). That percentage decreased to 40.5% when considering the point estimate of the HR. 50.0% of the trials had no published scorecard on the ESMO website and discrepancies affected 11 (26.2%) studies.…”

Data_Sheet_1_Long-Term Aortic Remodeling After Thoracic Endovascular Aortic Repair of Acute, Subacute, and Chronic Type B Dissections.docx by Zhenjiang Li (1448203)

“…</p>Results<p>After TEVAR, the true lumen (TL) dimension increased and the false lumen (FL) dimension decreased or did not change over a 5-year follow-up period in all three temporal groups. …”

Light-Driven Bending Crystals of Salicylidenephenylethylamines in Enantiomeric and Racemate Forms by Hideko Koshima (1825630)

“…The reversible bending of the achiral enol-(<i>rac</i>)-<b>1</b> crystal could be repeated over 100 times, while the tip displacement angles of the chiral enol-(<i>S</i>)-<b>1</b> and enol-(<i>R</i>)-<b>1</b> crystals gradually decreased with repeated cycles. In situ X-ray measurements revealed that the bending motion of the chiral and achiral crystals was caused by a slight shrinkage of the <i>a</i> and <i>b</i> axes of the unit cell, respectively, corresponding to the long axis of the platelike crystals; shrinkage was induced by the shape change of component salicylidenephenylethylamine molecules upon photoinduced proton transfer. …”

Table_3_Alterations in the Gut Microbiome of Individuals With Tuberculosis of Different Disease States.xlsx by Yue Wang (65477)

“…The purpose of the current study was to explore the alterations in gut microbiome under different tuberculosis disease stages in the Uyghur population, clarify the composition of microbial taxonomy, search for microbial biomarkers and provide innovative ideas for individual immune prevention and for control strategies.</p>Design<p>A case–control study of Uyghur individuals was performed using 56 cases of pulmonary tuberculosis (PTB), 36 cases of latent tuberculosis infection (LTBI) and 50 healthy controls (HC), from which stool samples were collected for 16S rRNA gene sequencing.…”

Light-Driven Bending Crystals of Salicylidenephenylethylamines in Enantiomeric and Racemate Forms by Hideko Koshima (1825630)

“…The reversible bending of the achiral enol-(<i>rac</i>)-<b>1</b> crystal could be repeated over 100 times, while the tip displacement angles of the chiral enol-(<i>S</i>)-<b>1</b> and enol-(<i>R</i>)-<b>1</b> crystals gradually decreased with repeated cycles. In situ X-ray measurements revealed that the bending motion of the chiral and achiral crystals was caused by a slight shrinkage of the <i>a</i> and <i>b</i> axes of the unit cell, respectively, corresponding to the long axis of the platelike crystals; shrinkage was induced by the shape change of component salicylidenephenylethylamine molecules upon photoinduced proton transfer. …”

Data_Sheet_1_Resveratrol Improves Growth Performance, Intestinal Morphology, and Microbiota Composition and Metabolism in Mice.docx by Yu Zhuang (2824982)

“…The current study was conducted to explore whether RSV alleviates weaning stress through improving gut health in a weaning mouse model. Forty 21-day-old weaned mice were randomly assigned to a control group without RSV treatment and three treatment groups with 10, 20, and 50 mg/kg RSV for 28 days.…”

Table_1_Next generations of CAR-T cells - new therapeutic opportunities in hematology?.docx by Jaromir Tomasik (14022519)

“…All registered treatments and most clinical trials are based on so-called 2nd generation CARs, which consist of an extracellular antigen-binding region, one costimulatory domain, and a CD3z signaling domain. Unfortunately, despite remarkable overall treatment outcomes, a relatively high percentage of patients do not benefit from CAR-T therapy (overall response rate varies between 50 and 100%, with following relapse rates as high as 66% due to limited durability of the response). …”

Light-Driven Bending Crystals of Salicylidenephenylethylamines in Enantiomeric and Racemate Forms by Hideko Koshima (1825630)

“…The reversible bending of the achiral enol-(<i>rac</i>)-<b>1</b> crystal could be repeated over 100 times, while the tip displacement angles of the chiral enol-(<i>S</i>)-<b>1</b> and enol-(<i>R</i>)-<b>1</b> crystals gradually decreased with repeated cycles. In situ X-ray measurements revealed that the bending motion of the chiral and achiral crystals was caused by a slight shrinkage of the <i>a</i> and <i>b</i> axes of the unit cell, respectively, corresponding to the long axis of the platelike crystals; shrinkage was induced by the shape change of component salicylidenephenylethylamine molecules upon photoinduced proton transfer. …”

Image_6_Alterations in the Gut Microbiome of Individuals With Tuberculosis of Different Disease States.tif by Yue Wang (65477)

“…The purpose of the current study was to explore the alterations in gut microbiome under different tuberculosis disease stages in the Uyghur population, clarify the composition of microbial taxonomy, search for microbial biomarkers and provide innovative ideas for individual immune prevention and for control strategies.</p>Design<p>A case–control study of Uyghur individuals was performed using 56 cases of pulmonary tuberculosis (PTB), 36 cases of latent tuberculosis infection (LTBI) and 50 healthy controls (HC), from which stool samples were collected for 16S rRNA gene sequencing.…”

Light-Driven Bending Crystals of Salicylidenephenylethylamines in Enantiomeric and Racemate Forms by Hideko Koshima (1825630)

“…The reversible bending of the achiral enol-(<i>rac</i>)-<b>1</b> crystal could be repeated over 100 times, while the tip displacement angles of the chiral enol-(<i>S</i>)-<b>1</b> and enol-(<i>R</i>)-<b>1</b> crystals gradually decreased with repeated cycles. In situ X-ray measurements revealed that the bending motion of the chiral and achiral crystals was caused by a slight shrinkage of the <i>a</i> and <i>b</i> axes of the unit cell, respectively, corresponding to the long axis of the platelike crystals; shrinkage was induced by the shape change of component salicylidenephenylethylamine molecules upon photoinduced proton transfer. …”

Light-Driven Bending Crystals of Salicylidenephenylethylamines in Enantiomeric and Racemate Forms by Hideko Koshima (1825630)

“…The reversible bending of the achiral enol-(<i>rac</i>)-<b>1</b> crystal could be repeated over 100 times, while the tip displacement angles of the chiral enol-(<i>S</i>)-<b>1</b> and enol-(<i>R</i>)-<b>1</b> crystals gradually decreased with repeated cycles. In situ X-ray measurements revealed that the bending motion of the chiral and achiral crystals was caused by a slight shrinkage of the <i>a</i> and <i>b</i> axes of the unit cell, respectively, corresponding to the long axis of the platelike crystals; shrinkage was induced by the shape change of component salicylidenephenylethylamine molecules upon photoinduced proton transfer. …”

Light-Driven Bending Crystals of Salicylidenephenylethylamines in Enantiomeric and Racemate Forms by Hideko Koshima (1825630)

“…The reversible bending of the achiral enol-(<i>rac</i>)-<b>1</b> crystal could be repeated over 100 times, while the tip displacement angles of the chiral enol-(<i>S</i>)-<b>1</b> and enol-(<i>R</i>)-<b>1</b> crystals gradually decreased with repeated cycles. In situ X-ray measurements revealed that the bending motion of the chiral and achiral crystals was caused by a slight shrinkage of the <i>a</i> and <i>b</i> axes of the unit cell, respectively, corresponding to the long axis of the platelike crystals; shrinkage was induced by the shape change of component salicylidenephenylethylamine molecules upon photoinduced proton transfer. …”

Table_2_Alterations in the Gut Microbiome of Individuals With Tuberculosis of Different Disease States.xlsx by Yue Wang (65477)

“…The purpose of the current study was to explore the alterations in gut microbiome under different tuberculosis disease stages in the Uyghur population, clarify the composition of microbial taxonomy, search for microbial biomarkers and provide innovative ideas for individual immune prevention and for control strategies.</p>Design<p>A case–control study of Uyghur individuals was performed using 56 cases of pulmonary tuberculosis (PTB), 36 cases of latent tuberculosis infection (LTBI) and 50 healthy controls (HC), from which stool samples were collected for 16S rRNA gene sequencing.…”

DataSheet_1_Dietary inclusion of blood hydrolysates affects muscle growth in European seabass (Dicentrarchus labrax).xlsx by Cristina Velasco (663138)

“…Three BH fractions were obtained by two different processes, autohydrolysis (AH-H) and enzymatic hydrolysis followed by micro- (RMF-H) and nanofiltration (RNF-H). Each BH was added to a commercial-based diet, where 50% of fishmeal was replaced by vegetable proteins (negative control, NC). …”

Excel file of raw lipidomics data. by Jody L. Gookin (10169432)

“…</p><p>Results</p><p>Gallbladder mucocele formation in dogs carried a unique lipidomic signature of increased lipogenesis impacting 50% of lipid classes, 36% of esterified fatty acid species, and 11% of complex lipid species. …”

Image_5_Alterations in the Gut Microbiome of Individuals With Tuberculosis of Different Disease States.tif by Yue Wang (65477)

“…The purpose of the current study was to explore the alterations in gut microbiome under different tuberculosis disease stages in the Uyghur population, clarify the composition of microbial taxonomy, search for microbial biomarkers and provide innovative ideas for individual immune prevention and for control strategies.</p>Design<p>A case–control study of Uyghur individuals was performed using 56 cases of pulmonary tuberculosis (PTB), 36 cases of latent tuberculosis infection (LTBI) and 50 healthy controls (HC), from which stool samples were collected for 16S rRNA gene sequencing.…”

Image_2_Alterations in the Gut Microbiome of Individuals With Tuberculosis of Different Disease States.tif by Yue Wang (65477)

“…The purpose of the current study was to explore the alterations in gut microbiome under different tuberculosis disease stages in the Uyghur population, clarify the composition of microbial taxonomy, search for microbial biomarkers and provide innovative ideas for individual immune prevention and for control strategies.</p>Design<p>A case–control study of Uyghur individuals was performed using 56 cases of pulmonary tuberculosis (PTB), 36 cases of latent tuberculosis infection (LTBI) and 50 healthy controls (HC), from which stool samples were collected for 16S rRNA gene sequencing.…”

Image_3_Alterations in the Gut Microbiome of Individuals With Tuberculosis of Different Disease States.tif by Yue Wang (65477)

“…The purpose of the current study was to explore the alterations in gut microbiome under different tuberculosis disease stages in the Uyghur population, clarify the composition of microbial taxonomy, search for microbial biomarkers and provide innovative ideas for individual immune prevention and for control strategies.</p>Design<p>A case–control study of Uyghur individuals was performed using 56 cases of pulmonary tuberculosis (PTB), 36 cases of latent tuberculosis infection (LTBI) and 50 healthy controls (HC), from which stool samples were collected for 16S rRNA gene sequencing.…”

Image_4_Alterations in the Gut Microbiome of Individuals With Tuberculosis of Different Disease States.tif by Yue Wang (65477)

“…The purpose of the current study was to explore the alterations in gut microbiome under different tuberculosis disease stages in the Uyghur population, clarify the composition of microbial taxonomy, search for microbial biomarkers and provide innovative ideas for individual immune prevention and for control strategies.</p>Design<p>A case–control study of Uyghur individuals was performed using 56 cases of pulmonary tuberculosis (PTB), 36 cases of latent tuberculosis infection (LTBI) and 50 healthy controls (HC), from which stool samples were collected for 16S rRNA gene sequencing.…”

Non-targeted GC/MS analysis of exhaled breath samples: Exploring human biomarkers of exogenous exposure and endogenous response from professional firefighting activity by M. Ariel Geer Wallace (2869187)

“…Fifty-seven out of 60 non-targeted features changed by at least 50% from pre- to post-fire suppression activity in at least one subject, and 7 non-targeted features were found to exhibit significantly increased or decreased concentrations for all subjects as a group. …”