Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes by Younes, Noura B.

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Ganji, Vijay

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Correlating the rheological and magneto-optical properties of cobalt substituted magnetite ferrofluids (CoxFe1?xFe2O4) with theoretical studies by Babukutty, B.

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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Aluminum nitride (AlN) reinforced electrodeposited Ni-B nanocomposite coatings by Radwan, A. Bahgat

“…The influence of addition of AlN nanoparticles (0.6 and 1.2 g L−1) on the morphological, mechanical and corrosion protection efficiency of Ni–B nanocomposite coatings was explored using SEM, XPS, XRD, AFM and electrochemical techniques. …”
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Using B4C nanoparticles to enhance thermal and mechanical response of aluminum by Ubaid, Fareeha

“…Mechanical characterization results revealed that hardness, elastic modulus, compression, and tensile strengths increased whereas ductility decreases with increasing B4C content. Al-1.0 vol. % B4C nanocomposite exhibited best hardness (135.56 Hv), Young's modulus (88.63 GPa), and compression/tensile strength (524.67/194.41 MPa) among the materials investigated. …”
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Nanoclay compatibilization of phase separated polysulfone/polyimide films for oxygen barrier by Ammar, Ali

“…Thermal decomposition (TGA) measurements of PSF/PI films showed a decrease in thermal stability upon adding C30B due to its surfactant modification, while film mechanical tensile modulus properties improved slightly by adding low concentration of C30B (~ 1 mass%), but higher nanoclay loading decreased tensile strength and elongation at break. …”
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Anticancer activity of Neosetophomone B, A Fungal Secondary Metabolite, against Hematological Malignancies by Kuttikrishnan, Shilpa

“…We tested a panel of leukemic cell lines with different doses of NSP-B. Cell viability decreased in a concentration-dependent manner in K562 and U937 cell lines. …”
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Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar by Abdelrahman, Doua

“…B19V genotyping showed a predominance of Genotype 1 (100%). …”
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Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor. by Padmanabhan, Regina

“…The combination decreased the cell's invasiveness along with altering several key pathways, such as Akt/mTor and ErbB2 compared to monotherapy. …”
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Pharmacoeconomic evaluation of voriconazole vs. liposomal amphotericin B in empiric treatment of invasive fungal infections in Turkey by Turner, Stuart J.

“…Univariate sensitivity analysis highlighted that increasing the duration of voriconazole by >1.2 days or decreasing LAmB by >1.0 days changes the result. …”
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Nanotargeted Delivery of Immune Therapeutics in Type 1 Diabetes by Jung, Sungwook

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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... by Thirumal Kumar, D

“…The molecular interaction study also revealed that the co-crystallized AKT1 inhibitor N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo [4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide (12j) exhibited a better interaction with native AKT1 compared with the E17K mutant AKT1 protein, whereas, Akti-1/2 exhibited the opposite effects, i.e., a better interaction with the E17K mutant AKT1 than the native AKT1. …”
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A Reverse MultipleChoice Based mLearning System by Karkar, AbdelGhani

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The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells. by Attafi, Ibraheem M

“…The toxic effects of Pb on the lung was associated with significant increases in NF-κB and AhR levels which was accompanied with increases in downstream targets genes, iNOS and CYP1A1, respectively. …”
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Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain by Mohammad H., Merii

“…In addition, nicotine individually decreased expression levels of all examined protein targets, significantly for CYP1B1 (p < 0.001), CYP19A1 (p = 0.010), AhRR (p = 0.042), and ARNT (p < 0.001), compared to control. …”
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Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts. by Ardah, Mustafa T

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Microwave-Assisted Solvothermal Synthesis of Mo-Doped TiO2 with Exceptional Textural Properties and Superior Adsorption Kinetics by Ahmad, Yahia H.

“…The average particle size ranged between 9.7 and 27.5 nm and it decreased with increasing the Mo content. Furthermore, Mo-TiO2 revealed mesoporous architectures with a high surface area ranging between 170 and 260 m2 g−1, which is superior compared to previously reported Mo-doped TiO2. …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

“…Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”
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The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy by Abdelaziz, Iman Ahmed

“…OPN appeared to contribute to NHE1-induced CH independent of extracellular-signal-regulated kinases, p90-ribosomal-S6 kinase and protein kinase B (Akt). …”
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