Mutation of the hydrophobic tip residues disrupts evoked transmitter release. by Matthew R. Bowers (8423115)

“…<p>The single hydrophobic mutation decreased neurotransmitter release by 50% while the double mutation inhibited release to a greater extent than that seen in <i>syt^null</i> mutants. …”

Comparison of whole genome prediction accuracy across generations using parametric and semi parametric methods by Abbas Atefi (10414497)

“…The genome comprised one chromosome of 100 cM length carrying 50 QTLs. There was no significant difference between accuracy of investigated methods (p > 0.05) but among three methods, the highest mean accuracy (0.659) was observed for BayesA. …”

Effects of age of exercise onset on body composition across the lifespan. by Agnieszka Mika (306138)

TLR4 and NF-κB signaling pathway is required for the reduction of let-7b expression in response to <i>H.pylori</i> infection. by Gui-gen Teng (380044)

“…<p>(A) TKA-242 (1 uM) decreased the expression of TLR4 protein in AGS and GES-1 cells with <i>H.pylori</i>-infection. …”

SOCS3 regulated the fate of HSCs. by Yu-xiao Liu (146872)

“…Bar = 50 μm. (B) BFU-E and CFU-E derived from shSOCS3-1 CD34⁺ cells. …”

Mechanism of SFK phosphorylation and negative regulation of PKA in chicken sperm. by Chathura Priyadarshana (9635328)

“…<p>Sperm were incubated with 0–50 μM H-89 (PKA inhibitor), 25 μM KH7 (sAC inhibitor), 50 μM MDL (tmAC inhibitor), 0–250 μM PTP inhibitor, or EGTA-AM in the presence or absence of SKI606 and SU6656 and then subjected to immunodetection for p-SFK-Y416 or p-PKAs. …”

Impact of Global <i>Fxr</i> Deficiency on Experimental Acute Pancreatitis and Genetic Variation in the <i>FXR - Figure 2 </i> Locus in Human Acute Pancreatitis by Rian M. Nijmeijer (208613)

Effect of hydrogen on CS-induced <i>muc5ac</i> expression in rat lung tissues. by Yunye Ning (500228)

“…<p>(a) Effect of hydrogen on CS-induced <i>muc5ac</i> transcription analyzed by realtime RT-PCR. …”

Supplemental Figure 1 by Chelsea Hutch (10156097)

<i>In vitro</i> fluorescence imaging and physicochemical characterization of the 3WJ-n × Bro fluorescent aptamer. by Sha Liu (80416)

“…T_m represents the temperature at which fluorescence intensity decreases to 50% of the initial value. Error bars represent mean ± SD (n = 5). …”

Data_Sheet_1_The Association Between Shift Work and Immunological Biomarkers in Nurses.PDF by Bjørn Bjorvatn (35254)

“…In contrast, MCP-1 levels were lower (large effect size) both after a day shift (22% decrease) and a night shift (12% decrease) compared with after a night of sleep.…”

Serum from HFD-induced obese rats and an artificial FA mixture suppress osteoblast differentiation. by Jin-Ran Chen (207037)

“…Cells were treated with 2% serum from LFD, MFD or HFD rats, 50 ng/ml Wnt3a, 400 µM FAs and their combination for 7 days in the presence or absence of osteogenic medium. …”

Effect of acupuncture on intraocular pressure and tear production in healthy horses by Thiene de Lima Rodrigues (12652431)

“…Meanwhile, IOP decreased in 50% of the animals at T5 and T30, in 20% at T15, in 60% at T60, and in 70% at T24. …”

The experimentally reported network parameters can generate supersaturation and be adapted to enter the inhibition-stabilized state. by Pierre Ekelmans (15470955)

“…This results in a decrease in the firing rates of both populations, as predicted by the SSN (dashed lines). …”

GUCY2C modulates systemic genotoxicity and tumorigenesis. by Jieru Egeria Lin (181534)

Characterization of the sexual development of deletion mutants for spore-enriched proteins. by Mingwei Huang (788799)

“…<p>(A) <i>rsc9Δ</i> strains show defects in mating, while <i>isp1Δ</i> and <i>bch1Δ</i> strains do not (top panels). …”

Quality controls for the TL high-throughput phenotyping approach. by Chenxi Qiu (706955)

“…(B) Additional growth conditions were employed to increase resolution for distinguishing similar TL alleles. Growth scores for 50 individually isolated TL mutants (y axis) under 12 growth conditions (x axis), as determined by standard serial dilution plate phenotyping (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006321#pgen.1006321.s004" target="_blank">S2</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1006321#pgen.1006321.s005" target="_blank">S3</a> Figs), are shown as a heatmap. …”

Effect of CN on IL-6, IL-1β, and TNF-α level of expression in MDA-MB-231/THP-1 co-culture. by Fariza Juliana Nordin (6287189)

“…<p>a) CN ethanol extract decreased IL-6 expression at 25- and 100 μg/mL but increased its expressions after treatment with CN aqueous extract at 50- and 100 μg/mL. b) CN ethanol extract inhibited the IL-1β expression at 25- and 100 μg/mL but not at 50 μg/mL. …”

Data_Sheet_1_Cerebrovascular Reactivity Assays Collateral Function in Carotid Stenosis.docx by Olivia Sobczyk (5412599)

“…Ipsilateral MCA territory CVR was less than normal in each class, including that with <50% stenosis (Student t-test, two-tailed; p = 0.0014 for GM and p = 0.030 for WM), with a trend of decreasing average CVR with increasing stenosis. …”

Age-dependent ASM at <i>MCHR1</i>. by Stefanie Stepanow (219536)

“…The GT allele exhibited a mean methylation of 22.9±6.7%, while the AC allele was 34.2±12.7% methylated. …”