Overexpression of eIF4EBP3L reduces and knockdown rescues Mef2c. by Orli Yogev (252096)

“…(D) Level of indicated mRNAs assayed by qPCR shows that BP3L morphants have reduced <i>eif4ebp3l</i> mRNA. (E) Western analysis shows that BP3L MO1 prevented decrease in Mef2c caused by inactivity compared to actin loading control. …”

AMD CIDEC variants in the CIDE-N domain decrease dimerization affinity and all four variants decrease binding to effector partners PLIN1, AS160 and RAB8A. by Sehyun Kim (2697172)

Antibody and antigen responses to Lufotrelvir vs placebo day 1–90. by Elizabeth S. Munroe (21568166)

Antibody and antigen responses to nMAb vs placebo day 1–90 for Sotrovimab. by Elizabeth S. Munroe (21568166)

Antibody and antigen responses by baseline anti-spike neutralizing response assay positivity. by Elizabeth S. Munroe (21568166)

Longitudinal antibody and antigen responses to treatment vs placebo day 1–90 for nMAbs, among patients alive and with day 90 antibody and antigen measures (Sensitivity Analysis). by Elizabeth S. Munroe (21568166)

MscL dependent decrease in viability in the presence of K05 and DHS. by Robin Wray (359090)

Antibody and antigen responses after treatment with nMAb vs placebo, day 1-90 (pooled nMAb treatments). by Elizabeth S. Munroe (21568166)

Effect of GluA2 RNAi on the dendritic morphology of E11 chicken lumbar motoneurons. by Yone J. Yoon (296191)

“…<p><i>A</i><b><i>–D</i></b><i>)</i> Infection of chicken embryos with the RCASBP(B)-RFP-GluA2 RNAi construct causes a significant decrease in the dendritic complexity of E11 motoneurons. …”

HRs, 95% CIs, and <i>p</i>-values for the association of duration of lithium exposure with the development of dementia (and its subtypes) by Cox proportional hazards models. by Shanquan Chen (3417512)

Subjects:

Fig 2 - by Veronika Mitterwallner (10323238)

Prolonged treatment with propofol does not decrease the neural stem cell pool. by Arvind Palanisamy (3159156)

Visual deprivation rescues the decrease in proliferative cells by HDAC1 knockdown. by Yi Tao (178829)

Variable-precision model of VWM. by Yi-Jie Zhao (11663148)

Hypothalamic AAV-TrkB.FL overexpression decreases body weight gain in HFD BTBR mice. by Jacqueline M. Anderson (14769007)

Data_Sheet_2_Impact of 6-Month Exposure to Aerosols From Potential Modified Risk Tobacco Products Relative to Cigarette Smoke on the Rodent Gastrointestinal Tract.xlsx by James N. D. Battey (10307402)

“…Candidate modified risk tobacco products (CMRTP) are being developed to provide substitute products to lower smoking-related health risks in smokers who are unable or unwilling to quit. In this study, the ApoE^–/– mouse model was used to investigate the impact of cigarette smoke (CS) from the reference cigarette 3R4F and aerosols from two CMRTPs based on the heat-not-burn principle [carbon-heated tobacco product 1.2 (CHTP 1.2) and tobacco heating system 2.2 (THS 2.2)] on the intestinal microbiome over a 6-month period. …”

Data_Sheet_1_Impact of 6-Month Exposure to Aerosols From Potential Modified Risk Tobacco Products Relative to Cigarette Smoke on the Rodent Gastrointestinal Tract.docx by James N. D. Battey (10307402)

“…Candidate modified risk tobacco products (CMRTP) are being developed to provide substitute products to lower smoking-related health risks in smokers who are unable or unwilling to quit. In this study, the ApoE^–/– mouse model was used to investigate the impact of cigarette smoke (CS) from the reference cigarette 3R4F and aerosols from two CMRTPs based on the heat-not-burn principle [carbon-heated tobacco product 1.2 (CHTP 1.2) and tobacco heating system 2.2 (THS 2.2)] on the intestinal microbiome over a 6-month period. …”

Suspension Induces Phosphorylation of eIF2α and Translation Repression in Mammary and Kidney Epithelial Cells. by Sharon J. Sequeira (55141)

“…<p>(A) Whole cell lysates from MCF10A (upper left), HEK293T (upper right) and primary HMEC (lower panels) cells grown either in adhered (A) or suspended conditions (S) as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000615#s4" target="_blank">methods</a> section for the indicated time points, were immunoblotted for p-eIF2α and total eIF2α levels. Adhered MCF10A or HEK293T cells treated with 2 mM DTT or 5 µg/ml tunicamycin (Tn) respectively, were used as positive controls. …”

Overview of the six original ACTIV-3/TICO trials. by Elizabeth S. Munroe (21568166)

Table1_Discontinuation of afterload-reducing drugs decreases left ventricular outflow tract obstruction in hypertrophic obstructive cardiomyopathy.docx by Anselm A. Derda (5866220)

“…</p>Results<p>16 patients discontinued their afterload-reducing drugs, resulting in a significant decrease in median LVOT gradient from 86.5 [60.5–109.3] mmHg to 61.5 [28.3–97.50] mmHg (p = 0.0004). …”