Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases by Xiao Li (107004)

“…Compared to the type I PRMT inhibitor from our previous work (DCPR049_12), ZL-28-6 showed increased potency against CARM1 and decreased activity against other type I PRMTs. Moreover, ZL-28-6 showed better antiproliferation activities toward a series of solid tumor cells than DCPR049_12, indicating its broad spectrum of anticancer activity. …”

Association of metabolic syndrome and psoriasis severity. by Dina Evyana (18462048)

Sociodemographic characteristic of the study population. by Dina Evyana (18462048)

Baseline clinical characteristic of the study population. by Dina Evyana (18462048)

Prevalence of metabolic syndrome (MetS) in hard-to-treat psoriasis. by Dina Evyana (18462048)

Mean cholera trajectories from Poisson model for different initial SES groups. by Elisabeth Dowling Root (103722)

Effect of variable Mean Fluorescent Intensity (MFI) on the identification of nucleotides in the consensus output. by Roger W. Barrette (845299)

“…Decreasing average MFI results in an overall reduction of correct nucleotides with an inverse increase in ambiguous nucleotides; seen as a shift in the 50% correct:unidentified ratio to a lower threshold. …”

Decreasing fitness over time observed following analysis of paired isolates obtained from acute HIV-1 infection subjects, measured using QPCR. by Alicia Arnott (242179)

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Study population: patients living with comorbidities (on the left) and immunosuppressive conditions (on the right) who are at risk of pneumococcal disease in France in the year 202... by Benjamin Wyplosz (22032756)

The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. by Tao Zhang (43681)

“…<p>Representative IHC stains of normal, normal-appearing FAP, and FAP adenomatous colonic crypts are shown for the expression of the: <b>(A)</b> NEC marker chromogranin-A (CGA). <b>(B)</b> SC marker ALDH1. …”

UV-irradiated M phase-cells show decreased MCM 2–7 loading and G1 arrest after release: HeLa cells. by Masayuki Morino (304956)

The Anion [Mg₆Cl₈Cp*₅]^-:  A Final Intermediate on the Way to the Molecular Donor-Free Grignard Compound MgClCp*? by Jean Vollet (2644651)

“…The reaction at −70 °C of decamethylmagnesocene MgCp*₂ (Cp* = pentamethylcyclopentadienyl) with monovalent aluminum chloride, AlCl, stabilized with diethyl ether and dissolved in toluene, results in tetrameric tetrahedrotetrakis(pentamethylcyclopentadienylaluminum), [AlCp*]₄, and the dimeric bis(pentamethylcyclopentadienylmagnesium chloride diethyl etherate), [MgCp*Cl·Et₂O]₂. At a slightly higher temperature and by stepwise decrease of the diethyl ether concentration before reaction, a preferred formation of metal clusters such as dodekakispentamethylcyclopentadienylpentaconta-aluminum, Al₅₀Cp*₁₂, was frequently observed. …”

PHA increased anti-oxidant gene expression and decreased NADPH oxidase and phospho-NF-kB p65⁺ microglia/macrophages. by Zhenying Han (621634)

Data_Sheet_1_Repeated Inoculation of Young Calves With Rumen Microbiota Does Not Significantly Modulate the Rumen Prokaryotic Microbiota Consistently but Decreases Diarrhea.docx by Dengpan Bu (369549)

Drop point and rebound rounds^a effects for groups in the empirical and simulated data. by Daniel B. Shank (709756)