Design, Synthesis, and Biological Evaluation of New PDE4 Inhibitors for the Treatment of Pressure Ulcers by Xudong Qian (13182676)

“…In a rat PU model, <b>G1</b> exhibited the capability to reduce the expression levels of inflammatory markers in skin tissue, diminish the thickness of the epidermal layer, decrease the number of dermal inflammatory cells, and significantly enhance the quantity of fibroblasts, which effectively expedited the wound healing process. …”

Untargeted Urinary Proteomics Uncovers Nephroprotective and Systemic Adaptations after Obesity Surgery-Induced Weight Loss by Pedro R. Pereira (6016460)

“…A decrease in inflammation protein markers (α-1-acid glycoproteins), alongside an increase in proteins associated with immune modulation and oxidative stress protection (dipeptidase 1, heat shock cognate 71 kDa protein) were observed. …”

Concept of heat-dissipation time as a fundamental constraint to the realised travel speeds of animals. by Alexander Dyer (15314519)

“…In order for the core body temperature to remain stable, a fraction of the total time budget is allocated towards heat-dissipation to offset the heat that is produced during locomotion; this takes place cyclically at small time-steps (e.g., between each stride). An increase in heat-dissipation time, therefore, corresponds to a reduced stride frequency and a net decrease in the realised travel speed. …”

<b>L-Tryptophan as a Frontier in Diabetes Management: A Pilot Study</b> by dr.gayathri M rao (22045067)

“…On 11th day after sacrifice, Intestinal absorption of glucose, Pancreatic and intestinal Na+-K+ ATPase (NKA) activity, intestinal Nitric Oxide (NO), Blood & pancreatic Glucagon like peptide-1(GLP-1), serum total protein, urea and cholesterol, liver and pancreatic histology were studied.</p><p dir="ltr">A significant decrease in the glucose absorption and blood glucose level in the tryptophan treated diabetic group in comparison with diabetic controls. …”

Depletion of DOM-A, but not DOM-B affects s-LN_vs maintenance and PDF accumulation. by Zhenxing Liu (399809)

“…Cell number of sLN_vs (marked as square brackets), PDF, PER and TIM levels in sLN_vs were decreased in <i>dom</i> and <i>domA</i> downregulation flies brains (Top right and bottom left panels), while only affected PER and TIM levels in <i>domB</i> downregulation flies (Bottom right panel). …”

Image_2_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

Image_2_Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling.TIFF by Kristy E. Gilman (11163543)

“…Combined, these data suggest a mechanism whereby irradiation-induced PGE₂ signaling to JNK blocks critical steps in saliva secretion manifested by a decrease in the quality (diminished amylase) and quantity (loss of calcium channel activity) of saliva, that can be restored with indomethacin. …”

The average performance of two-sample testing approaches with smaller population. by Ioannis Bargiotas (3390458)

“…<p>The dataset size was progressively decreased by a step of 10%. The included subset of each step was selected uniformly at random 12 times and the tests run in every iteration. …”

Sudden change from skewed distributions. by Ariel Burman (20329776)

Orientational Switch of the Lipase A Enzyme at the Oil–Water Interface: An Order of Magnitude Increase in Turnover Rate with a Single Surfactant Tag Explained by Sudip Das (3120951)

Percentage of total disasters triggering international aid appeal by years. by Lenard Cheng (16007166)

Characterization of hematopoietic stem and progenitor cells from BM of young and aged KO-F mice vs. by Ling Tian (107492)

Sample characteristics throughout the study duration. by Alexander J. Ehrenberg (10880032)

“…<p>(A) The proportion of samples (n = 11,971) that returned with a specimen insufficient value decreased throughout the study. The teal-colored band represents samples that were rejected in a step before PCR analysis, such as an inability to pipette. …”

HCV RNA was quantified by RT-QPCR after infection in stable cell lines. by Sobia Manzoor (11372369)

GO annotation analyses of DEGs. by Benzun Wei (21485639)

Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations by Han Liu (288039)

“…Furthermore, we identify that postglycosylation noncovalent polysaccharide chain transfer emerges as the decisive factor in cyclization, particularly for AM–degree of polymerization (DP) greater than 30 substrate complexes, where this noncovalent step (≥13.6 kcal/mol) dictates the rate of CA production. 57 variants with enhanced activity (up to a 2.3-fold increase) were engineered in our biochemical experiments by strategically modulating the chain transfer step. …”

Plasmid constructs used in this study. by Zahra Hosseininia (22265113)

“…The <i>PRAME-AS</i> knockout cells showed a decrease in migration, proliferation, stemness, and viability. …”

Oligonucleotides used in this study. by Zahra Hosseininia (22265113)

“…The <i>PRAME-AS</i> knockout cells showed a decrease in migration, proliferation, stemness, and viability. …”

Results of the GLMMs to test for the association between RA and richness of reservoir and non-reservoir species. by Hugo Mendoza (11264458)

Characteristics of Gasless Combustion of Core–Shell Al@NiO Microparticles with Boosted Exothermic Performance by Shina Maini (19413980)

“…The PM composite was not able to be ignited at all by a 5 W laser, while the core–shell counterpart ignited at 2.55 ms and was completely combusted within 6.50 ms accompanying a violent impulse.…”