REG-O3 chimeric peptide combining growth hormone and somatostatin sequences improves joint function and prevents cartilage degradation in rat model of traumatic knee osteoarthritis by Rodrick Montjean (400649)

“…The effect of REG-O3, solubilized in a liposomal solution and injected at either 5, 25 or 50 μg/50 μL, was compared to liposomal (LIP), dexamethasone and hyaluronic acid (HA) solutions. …”

Apoptosis is enhanced in DCE- or CS-treated keratinocytes. by Claudia Scarponi (205759)

The probability of emergence of vector-borne diseases. by Romulus Breban (24867)

“…Note that, with decreasing mutation rate, the probability curve develops a hyperbolic trend in the vicinity of .…”

Noncovalent Interaction- and Steric Effect-Controlled Regiodivergent Selectivity in Dimeric Manganese-Catalyzed Hydroarylation of Internal Alkynes: A Computational Study by Congcong Huang (1372224)

“…Alkyne migratory insertion is considered as the regioselectivity-determining step. Energy decomposition analyses on insertion transition states suggest that the interaction between the substrate and catalyst is mainly responsible for the observed exclusive γ-selectivity of <b>1a</b>, while the deformation of these two sections induced by the sterically hindered phenyl group and aryl group accounts for the complete β-position arylation of <b>1e</b>. …”

Representative data from primary HTS. by Pamela Y. Ting (713174)

Working model for REG-O3 mechanism of action. by Rodrick Montjean (400649)

Plot of adjusted risk ratios of high SARS-CoV-2 viral load upon presentation to the emergency department for each study day compared to the first day of the study that includes an... by Michael J. Satlin (9160569)

Sensitivity of U251 stable clones to GCV. by Elizabeth Wei-Chia Luo (11250668)

“…<p>U251, U251-pCMV-HSVtk, and U251-pGFAP-HSVtk cells were treated with 0, 1, 5, or10 μg/ml of GCV for 5 days. (A–D) Live-cell phase images of U251 parent cells displayed no cytotoxicity up to 10 μg/ml of GCV. …”

Expression of Glo-I and MGO in whole rat liver. by Marcus Hollenbach (376231)

3D spheroids enhance NFAT3 and CXCR4 expression. by Keven Huang (675616)

“…(<b>C</b>) Corresponding to the increase in NFAT3 in 3D spheroids, real-time PCR showed a 30-50-fold increase in CXCR4 mRNA in 3D spheroids when compared to adherent HeyA8 cells. (*, P <0.05 vs Adh, 1-way ANOVA). …”

Extended experimental procedures. by Debabrata Tripathy (784509)

Fusion of a granzyme B-mCherry containing lytic granule with the plasma membrane. by Min Ming (785996)

“…(<i>C</i>) The whole-cell membrane capacitance trace (C_m, upper trace) and the camera trigger voltage are shown (lower trace, positive steps indicate shutter opening) versus time. The capacitance step in the C_m trace at time 48.2 s occurs at video frame 535 (arrow).…”

Patterns of nestin, GFAP, and βIII-tubulin expression in U251-pCMV-HSVtk cells. by Elizabeth Wei-Chia Luo (11250668)

“…Immunocytochemistry of nestin (A–F), GFAP (G–L), and βIII-tubulin (M–R, M′–R′) was performed to characterize the identity of surviving cells. …”

Study area (a), location of 52 sediment collection devices (b) and photograph of one of the collection devices in the field, western USA. by Andrew Kulmatiski (833256)

Frequency-dependent effects of FSK on AHP and Kv2.1 current. by Luis I. Angel-Chavez (736879)

Generation of an acoziborole-resistant cell line and analysis of cross-resistance. by Pieter C. Steketee (10024552)

Relative gene expression of neural stem cell and lineage specific markers in hMSC populations throughout growth phases. by Rachel K. Okolicsanyi (794011)

Identification of Small Molecules that Disrupt Signaling between ABL and Its Positive Regulator RIN1 by Pamela Y. Ting (713174)

“…This assay was used in a high throughput screen (HTS) of two small molecule libraries totaling 444,743 compounds. 708 confirmed hits were counter-screened to eliminate off-target inhibitors and reanalyzed to prioritize compounds with IC₅₀ values below 10 μM. …”

Role of the MAPK pathway in human lung epithelial-like A549 cells apoptosis induced by paraquat by Da-Zhuang Sun (8650728)

DataSheet_1_Disruptive effects of plasticizers bisphenol A, F, and S on steroidogenesis of adrenocortical cells.docx by Benedikt Pötzl (18854980)

“…However, when combining all three bisphenols, additive effects were detected: e.g. 11-deoxycortisosterone was decreased at doses >10µM (FC 0.27±0.04, p≤0.0001, at 25µM), whereas 21-deoxycortisol was increased by 2.92±0.20 (p≤0.01) at 10µM, and by 3.21±0.45 (p≤0.001) at 50µM. …”