Loss of Specific Active-Site Iron Atoms in Oxygen-Exposed [FeFe]-Hydrogenase Determined by Detailed X‑ray Structure Analyses by Julian Esselborn (1610584)

“…We thus propose two parallel processes: dissociation of the distal Fe atom and 4Fe_H interconversion. …”

Study population characteristics. by Joel N. Meyer (249728)

“…A subset of 27 and 26 veterans returned for second and third visits, allowing us to measure stability of mitochondrial parameters over time. mtDNA CN, mtDNA damage, ATP-linked OCR, and spare respiratory capacity were moderately replicable over time, with intraclass correlation coefficients of 0.43, 0.44, 0.50, and 0.57, respectively. …”

Table 1_Bifidobacterium compound preparations as a supplementary treatment for severe ischemic stroke: a systematic review and meta-analysis.docx by Shenghua Lu (20762612)

“…Regarding immune function, the BCP combination group significantly increased IgA (MD = 0.50, 95% CI 0.36 to 0.63, p < 0.00001) and IgG (MD = 3.00, 95% CI 2.03 to 3.97, p < 0.00001). …”

Ethanol Inhibits Activation of NLRP3 and AIM2 Inflammasomes in Human Macrophages–A Novel Anti-Inflammatory Action of Alcohol by Katariina Nurmi (482194)

“…</p><p>Results</p><p>Ethanol decreased dose-dependently the production of mature IL-1β induced by activators of the NLRP3 inflammasome, i.e. …”

Description of the cohort (N = 118 patients). by Bastien Le Floc’h (14773916)

“…An HLA-G plasma level ≤ 50 ng/ml on day 8 after LT was significantly associated with a higher rejection risk. …”

Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway by Sampath, Chethan

“…Major dicarbonyl compounds such as methylglyoxal or glyoxal are found to be the main precursors of AGEs and N(e)-(carboxymethyl)lysine (CML) found to be predominantly higher in the diabetic population. We hypothesized that phloretin from apple and [6]-gingerol from ginger inhibit formation of AGEs and suppress the receptor for advanced glycation end products (RAGE) via nuclear factor erythroid-2- related-factor-2 (Nrf2)-dependent pathway. …”
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Probability of establishing a sylvatic ZIKV transmission cycle. by Benjamin M. Althouse (116177)

“…Other parameters: mean mosquito lifespan = 7 days; mean ZIKV recovery in NHP = 4 days; mosquito vertical transmission of ZIKV = 0; rate of yearly ZIKV introduction = 0.…”

Exploring the Scope of the 29G12 Antibody Catalyzed 1,3-Dipolar Cycloaddition Reaction by Jonathan D. Toker (2668999)

“…An analysis of the temperature dependence of the 29G12-catalyzed reaction between <b>1a</b> and <b>2m</b> reveals that catalysis is achieved via a decrease in enthalpy of activation (ΔΔ<i>H</i>^⧧ 4.4 kcal mol^-1) and involves a large increase in the entropy of activation (ΔΔ<i>S</i>^⧧ 10.4 eu). …”

Survival after breast cancer in women with type 2 diabetes using antidiabetic medication and statins: a retrospective cohort study by Mayu Hosio (8916941)

“…<p><b>Background:</b> We assessed survival of breast cancer in women with type 2 diabetes (T2D) treated with metformin, other types of antidiabetic medication (ADM) and statins.…”

The Fucosylation Inhibitor, 2-Fluorofucose, Inhibits Vaso-Occlusion, Leukocyte-Endothelium Interactions and NF-ĸB Activation in Transgenic Sickle Mice by John D. Belcher (190588)

“…Because P- and E-selectin are required for vaso-occlusion in murine sickle cell disease (SCD), we investigated whether 2FF would inhibit vaso-occlusion in SCD mice. …”

S1 Dataset - by Chenyi Xia (11283023)

“…Administration of GBE50 regulated the activities of these three enzymes and induced a decrease in H₂O₂. …”

FGF-2 Deficiency Does Not Influence FGF Ligand and Receptor Expression during Development of the Nigrostriatal System by Andreas Ratzka (183750)

“…In this study, we determined the expression profiles of all 22 <em>FGF-ligands</em> and 10 <em>FGF-receptor</em> isoforms, in order to clarify, if FGF-2 deficiency leads to compensatory up-regulation of other FGFs in the nigrostriatal system. …”

Image 1_Sulforaphane acutely activates multiple starvation response pathways.jpeg by Kendra S. Plafker (2379379)

“…SFN treatment (i) increased mitochondrial mass and resistance to oxidative stress, (ii) acutely suppressed markers of mTORC1/2 activity via inhibition of insulin signaling, (iii) upregulated autophagy and further amplified autophagic flux induced by rapamycin or nutrient deprivation while concomitantly promoting lysosomal biogenesis, and (iv) acutely decreased glucose uptake and lactate secretion followed by an adaptive rebound that coincided with suppressed protein levels of thioredoxin-interacting protein (TXNIP) due to early transcriptional down-regulation. …”

Supplementary Material for: Quantitative Profiling and Identification of Plasma Proteins of Spinocerebellar Ataxia Type 2 Patients by Swarup V. (4137157)

“…<b><i>Objective:</i></b> In this study, we investigated the blood plasma of SCA2 patients to find protein biomarkers. …”

Table 3_Sulforaphane acutely activates multiple starvation response pathways.xlsx by Kendra S. Plafker (2379379)

“…SFN treatment (i) increased mitochondrial mass and resistance to oxidative stress, (ii) acutely suppressed markers of mTORC1/2 activity via inhibition of insulin signaling, (iii) upregulated autophagy and further amplified autophagic flux induced by rapamycin or nutrient deprivation while concomitantly promoting lysosomal biogenesis, and (iv) acutely decreased glucose uptake and lactate secretion followed by an adaptive rebound that coincided with suppressed protein levels of thioredoxin-interacting protein (TXNIP) due to early transcriptional down-regulation. …”

Table 1_Sulforaphane acutely activates multiple starvation response pathways.xlsx by Kendra S. Plafker (2379379)

“…SFN treatment (i) increased mitochondrial mass and resistance to oxidative stress, (ii) acutely suppressed markers of mTORC1/2 activity via inhibition of insulin signaling, (iii) upregulated autophagy and further amplified autophagic flux induced by rapamycin or nutrient deprivation while concomitantly promoting lysosomal biogenesis, and (iv) acutely decreased glucose uptake and lactate secretion followed by an adaptive rebound that coincided with suppressed protein levels of thioredoxin-interacting protein (TXNIP) due to early transcriptional down-regulation. …”

Tuning Maps for Two-Photon Absorption Cross Sections of Canonical and Noncanonical Fluorescent Protein Chromophores by Ryan Johannson (6269363)

“…In this work, we present electrostatic tuning maps, created by placing partial charges along the van der Waals radii of eight different chromophores: Green FP (neutral and anion), Red FP (neutral and anion), mBlueberry FP, Kusabira orange FP, and two noncanonical chromophores, a hydroxyquinolone derivative, and the chromophore of Gold FP. 2PA cross sections (σ^2PA) were calculated at the CAM-B3LYP/aug-cc-pVDZ level of theory with and without the presence of point charges. …”

Tuning Maps for Two-Photon Absorption Cross Sections of Canonical and Noncanonical Fluorescent Protein Chromophores by Ryan Johannson (6269363)

“…In this work, we present electrostatic tuning maps, created by placing partial charges along the van der Waals radii of eight different chromophores: Green FP (neutral and anion), Red FP (neutral and anion), mBlueberry FP, Kusabira orange FP, and two noncanonical chromophores, a hydroxyquinolone derivative, and the chromophore of Gold FP. 2PA cross sections (σ^2PA) were calculated at the CAM-B3LYP/aug-cc-pVDZ level of theory with and without the presence of point charges. …”

Tuning Maps for Two-Photon Absorption Cross Sections of Canonical and Noncanonical Fluorescent Protein Chromophores by Ryan Johannson (6269363)

“…In this work, we present electrostatic tuning maps, created by placing partial charges along the van der Waals radii of eight different chromophores: Green FP (neutral and anion), Red FP (neutral and anion), mBlueberry FP, Kusabira orange FP, and two noncanonical chromophores, a hydroxyquinolone derivative, and the chromophore of Gold FP. 2PA cross sections (σ^2PA) were calculated at the CAM-B3LYP/aug-cc-pVDZ level of theory with and without the presence of point charges. …”

ELECTRODE SUSPENSION FOR AQUEOUS SODIUM FLOW BATTERY by MESLAM, MENTALLAH MOHAMED HASSANIN MOHAMED HASSANIN

“…In the current study, we attempt to formulate and characterize aqueous electrode suspensions (anolytes) composed of carbon black (KB) and sodium titanate (Na2Ti3O7; NTO) dispersed in branched micelle solution. …”
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