Image_2_Functional Disorganization of Small-World Brain Networks in Patients With Ischemic Leukoaraiosis.tif by Yixin Zhu (8174733)

“…Graph theory-based analyses were employed to explore the topological organization of the brain connectome in ILA patients, and we further sought to explore the associations of connectome-based metrics and neuropsychological performances. …”

Image_2_Potential of Pectins to Beneficially Modulate the Gut Microbiota Depends on Their Structural Properties.pdf by Nadja Larsen (253461)

“…This study characterized the relationship between the structural properties of pectins and their potential to modulate composition and activity of the gut microbiota in a beneficial way. For this purpose we performed in vitro fermentations of nine structurally diverse pectins from citrus fruits and sugar beet, and a pectic derivative, rhamnogalacturonan I (RGI), using a TIM-2 colon model. …”

In vivo reporter assays uncover changes in enhancer activity caused by type 2 diabetes associated SNPs by Ada Admin (8524211)

“…We performed <i>in vivo</i> mosaic transgenesis assays in zebrafish to quantitatively test the enhancer activity of type 2 diabetes-associated <i>loci</i>. …”

Isomeric Mono-, Di-, and Tri-Bromobenzo-1H-Triazoles as Inhibitors of Human Protein Kinase CK2α by Romualda Wąsik (119538)

“…<div><p>To further clarify the role of the individual bromine atoms of 4,5,6,7-tetrabromotriazole (TBBt), a relatively selective inhibitor of protein kinase CK2, we have examined the inhibition (IC₅₀) of human CK2α by the two mono-, the four di-, and the two tri- bromobenzotriazoles relative to that of TBBt. …”

Supplementary file 1_The bridge between anxiety and insomnia symptoms among Chinese adults before and after SARS-CoV-2 vaccination: a network analysis.doc by Yan Liu (25061)

“…The numbers of participants differed much in the two groups.</p>Conclusions<p>The proportion of participants experiencing anxiety and insomnia decreased significantly after SARS-CoV-2 vaccination. …”

Table_2_Comprehensive proteome, phosphoproteome and kinome characterization of luminal A breast cancer.xlsx by Ganglong Yang (778465)

“…Invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) are the two most common histological subtypes of breast cancer. …”

Table_2_Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases.DOCX by Sarah Y. Weißenberg (7420550)

“…Functional studies to overcome B cell hyporesponsiveness revealed that CD40 co-stimulation increased BCR signaling, induced proliferation, and downregulated PTP expression (PTPN2, PTPN22, and receptor-type PTPs). The data support the conclusion that hyporesponsiveness of AID and especially SLE B cells results from chronic in vivo stimulation through the BCR without T cell help mediated by CD40–CD154 interaction and is manifested by decreased phosphorylation of BCR-related proximal signaling molecules and increased PTPs. …”

Data Sheet 1_Identification of mitochondria-related feature genes for predicting type 2 diabetes mellitus using machine learning methods.csv by Xiuping Xuan (8686266)

“…Purpose<p>We aimed to identify the mitochondria-related feature genes associated with type 2 diabetes mellitus and explore their potential roles in immune cell infiltration.…”

Data Sheet 4_Identification of mitochondria-related feature genes for predicting type 2 diabetes mellitus using machine learning methods.csv by Xiuping Xuan (8686266)

“…Purpose<p>We aimed to identify the mitochondria-related feature genes associated with type 2 diabetes mellitus and explore their potential roles in immune cell infiltration.…”

Data Sheet 6_Identification of mitochondria-related feature genes for predicting type 2 diabetes mellitus using machine learning methods.csv by Xiuping Xuan (8686266)

“…Purpose<p>We aimed to identify the mitochondria-related feature genes associated with type 2 diabetes mellitus and explore their potential roles in immune cell infiltration.…”

Incremental Genetic Perturbations to MCM2-7 Expression and Subcellular Distribution Reveal Exquisite Sensitivity of Mice to DNA Replication Stress by Chen-Hua Chuang (242254)

“…<em>Mcm4^{Chaos3/Chaos3}</em> embryonic fibroblasts have ∼40% reduction in all MCM proteins, coincident with reduced <em>Mcm2-7</em> mRNA. Further genetic reductions of <em>Mcm2</em>, <em>6</em>, or <em>7</em> in this background caused various phenotypes including synthetic lethality, growth retardation, decreased cellular proliferation, GIN, and early onset cancer. …”

Data Sheet 3_Identification of mitochondria-related feature genes for predicting type 2 diabetes mellitus using machine learning methods.csv by Xiuping Xuan (8686266)

“…Purpose<p>We aimed to identify the mitochondria-related feature genes associated with type 2 diabetes mellitus and explore their potential roles in immune cell infiltration.…”

Table 1_RETRACTED: Annao Pingchong decoction attenuates oxidative stress and neuronal apoptosis following intracerebral hemorrhage via RAGE-NOX2/4 axis.docx by Xu Wang (28596)

“…Additionally, it suppressed the RAGE-NOX2/4 signaling axis and neuronal apoptosis.</p>Conclusion<p>ANPCD exhibits neuroprotective effects by inhibiting the RAGE-NOX2/4 signaling axis, thereby alleviating neuronal oxidative stress and apoptosis following ICH.…”

Table 1_Annao Pingchong decoction attenuates oxidative stress and neuronal apoptosis following intracerebral hemorrhage via RAGE-NOX2/4 axis.docx by Xu Wang (28596)

“…Additionally, it suppressed the RAGE-NOX2/4 signaling axis and neuronal apoptosis.</p>Conclusion<p>ANPCD exhibits neuroprotective effects by inhibiting the RAGE-NOX2/4 signaling axis, thereby alleviating neuronal oxidative stress and apoptosis following ICH.…”

Image 1_Identification of mitochondria-related feature genes for predicting type 2 diabetes mellitus using machine learning methods.jpeg by Xiuping Xuan (8686266)

“…Purpose<p>We aimed to identify the mitochondria-related feature genes associated with type 2 diabetes mellitus and explore their potential roles in immune cell infiltration.…”

Image 3_Identification of mitochondria-related feature genes for predicting type 2 diabetes mellitus using machine learning methods.jpeg by Xiuping Xuan (8686266)

“…Purpose<p>We aimed to identify the mitochondria-related feature genes associated with type 2 diabetes mellitus and explore their potential roles in immune cell infiltration.…”

Data Sheet 5_Identification of mitochondria-related feature genes for predicting type 2 diabetes mellitus using machine learning methods.csv by Xiuping Xuan (8686266)

“…Purpose<p>We aimed to identify the mitochondria-related feature genes associated with type 2 diabetes mellitus and explore their potential roles in immune cell infiltration.…”

Investigating the Mechanism of Hyperglycemia-Induced Fetal Cardiac Hypertrophy by Sha-sha Han (801205)

“…PH3 immunofluorescent staining of mouse fetal hearts and <i>in vitro</i>-cultured H9c2 cells indicated that cell proliferation decreased in E18.5, E15.5 and E13.5 mice, and cell apoptosis in H9c2 cells increased in the presence of high glucose in a dose-dependent manner. …”

Table1_Relationship of PIEZO1 and PIEZO2 vascular expression with diabetic neuropathy.DOCX by Yolanda Garcia-Mesa (17416872)

“…Finally, this study points out a possible correlation between increased vascular Piezo2 immunostaining and pain and decreased vascular Piezo1 immunostaining and the development of vasodilation deficiency.…”

Image_3_TOP2A correlates with poor prognosis and affects radioresistance of medulloblastoma.tif by Yufeng Zhang (195768)

“…In this study, we found that TOP2A was significantly upregulated in MB, and high expression of TOP2A related to poor prognosis of MB patients. …”