Table5_Low FNDC5/Irisin expression is associated with aggressive phenotypes in gastric cancer.XLSX by Luyun Xu (11460052)

“…</p><p>Results: The expression of FNDC5 was decreased in gastric cancer tissues compared to normal gastric tissues. …”

Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in <i>Trypanosoma cruzi</i> by Chantal Reigada (3844975)

“…Isotretinoin inhibited the polyamine transport, as well as other amino acid transporters from the same protein family (<i>Tc</i>AAAP), with calculated IC₅₀ values in the range of 4.6–10.3 μM. It also showed a strong inhibition of trypomastigote burst from infected cells, with calculated IC₅₀ of 130 nM (SI = 920) being significantly less effective on the epimastigote stage (IC₅₀ = 30.6 μM). …”

Data_Sheet_1_Overexpression of MsASMT1 Promotes Plant Growth and Decreases Flavonoids Biosynthesis in Transgenic Alfalfa (Medicago sativa L.).docx by Huifang Cen (5077895)

“…Compared with wild-type (WT) plants, MsASMT1 overexpression (OE-MsASMT1) plants exhibited a series of phenotypic changes, including vigorous growth, increased plant height, enlarged leaves and robust stems with increased cell sizes, cell numbers and vascular bundles, as well as more branches. We also found that the flavonoid content and lignin composition of syringyl to guaiacyl ratio (S/G) were decreased and the cellulose content was increased in OE-MsASMT1 transgenic alfalfa. …”

Decreased expression of 14-3-3 θ, β, γ, and Chk1 protects against Vpr- and HIV-1 (-)-induced cell cycle arrest by Diane L Bolton (92098)

<i>Bbs1</i>^{<i>M390R/M390R</i>} mice have decreased hippocampal proliferation. by Thomas K. Pak (10686881)

“…The Red Bar line represents 50μm. G.) Decreased proliferation in the dentate gyrus of P3 <i>Bbs1</i>^{<i>M390R/M390R</i>} mice. …”

Patient data. by Alexander Neugebauer (2425123)

“…</p><p>Results</p><p>On average, the time required to move through the obstacle course decreased by 17.0% after the training phase, the number of collisions decreased by 50.0%. …”

Data_Sheet_1_Transcriptome Analysis of Ovarian Follicles Reveals Potential Pivotal Genes Associated With Increased and Decreased Rates of Chicken Egg Production.docx by Xiaoxia Chen (2163943)

ALVAC-HIV elicits V2, V3, and CD4 inducible (CD4i) binding antibody responses. by LaTonya D. Williams (3140490)

Decrease of citric acid produced by <i>Aspergillus niger</i> through disruption of the gene encoding a putative mitochondrial citrate-oxoglutarate shuttle protein by Kohtaro Kirimura (414508)

Early Stages of Sea-Level Rise Lead To Decreased Salt Marsh Plant Diversity through Stronger Competition in Mediterranean-Climate Marshes - Fig 2 by Akana E. Noto (3623366)

Exercise training decreases 4-HNE modification of proteasome and re-establishes cardiac ubiquitin-proteasome system function in myocardial infarction-induced heart failure. by Juliane C. Campos (145308)

Reduction of the mean absolute error (MAE) in time for all participant on x-axis. by Almoctar Hassoumi (6470354)

“…<p>A similar effect is observed for y-axis. The MAE obtained using the standard regression (orange circles) decreased significantly when using symbolic regression. …”

Psoriatic lesion in some of the hard-to-treat areas of the study population. by Dina Evyana (18462048)

Delayed boosting with ALVAC-HIV/AIDSVAX B/E or AIDSVAX B/E increases breadth of Env-specific IgG response. by LaTonya D. Williams (3140490)

Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis by Chenlu Zhang (508309)

“…Evidence showed that intestinal FXR antagonism exhibited remarkable metabolic improvements in mice. Herein, we developed a series of betulinic acid derivatives as potent intestinal FXR antagonists, and <b>F6</b> was identified as the most potent one with an IC₅₀ at 2.1 μM. …”

Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis by Chenlu Zhang (508309)

“…Evidence showed that intestinal FXR antagonism exhibited remarkable metabolic improvements in mice. Herein, we developed a series of betulinic acid derivatives as potent intestinal FXR antagonists, and <b>F6</b> was identified as the most potent one with an IC₅₀ at 2.1 μM. …”

Image_3_Decrease of GSK-3β Activity in the Anterior Cingulate Cortex of Shank3b−/− Mice Contributes to Synaptic and Social Deficiency.TIF by Mengmeng Wang (540017)

“…From 4 weeks post-birth, neurons in Shank3b^−/− ACC exhibited an obvious decrease in spine density and stubby spines. The length and thickness of post-synaptic density (PSD), the expression of vesicular glutamate transporter 2 (vGlut2) and glutamate receptor 2 (GluR2), and the frequency of miniature excitatory post-synaptic currents (mEPSCs) were significantly reduced in Shank3b^−/−ACC. …”

Image_1_Decrease of GSK-3β Activity in the Anterior Cingulate Cortex of Shank3b−/− Mice Contributes to Synaptic and Social Deficiency.tif by Mengmeng Wang (540017)

“…From 4 weeks post-birth, neurons in Shank3b^−/− ACC exhibited an obvious decrease in spine density and stubby spines. The length and thickness of post-synaptic density (PSD), the expression of vesicular glutamate transporter 2 (vGlut2) and glutamate receptor 2 (GluR2), and the frequency of miniature excitatory post-synaptic currents (mEPSCs) were significantly reduced in Shank3b^−/−ACC. …”

Image_4_Decrease of GSK-3β Activity in the Anterior Cingulate Cortex of Shank3b−/− Mice Contributes to Synaptic and Social Deficiency.TIF by Mengmeng Wang (540017)

“…From 4 weeks post-birth, neurons in Shank3b^−/− ACC exhibited an obvious decrease in spine density and stubby spines. The length and thickness of post-synaptic density (PSD), the expression of vesicular glutamate transporter 2 (vGlut2) and glutamate receptor 2 (GluR2), and the frequency of miniature excitatory post-synaptic currents (mEPSCs) were significantly reduced in Shank3b^−/−ACC. …”

Image_2_Decrease of GSK-3β Activity in the Anterior Cingulate Cortex of Shank3b−/− Mice Contributes to Synaptic and Social Deficiency.TIF by Mengmeng Wang (540017)

“…From 4 weeks post-birth, neurons in Shank3b^−/− ACC exhibited an obvious decrease in spine density and stubby spines. The length and thickness of post-synaptic density (PSD), the expression of vesicular glutamate transporter 2 (vGlut2) and glutamate receptor 2 (GluR2), and the frequency of miniature excitatory post-synaptic currents (mEPSCs) were significantly reduced in Shank3b^−/−ACC. …”