Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization by Yin Yuan (597540)

“…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …”

Aflatoxin B₁ Negatively Regulates Wnt/β-Catenin Signaling Pathway through Activating miR-33a by Yi Fang (287944)

“…The level of miR-33a was up-regulated in hepatocellular carcinoma (HCC) cells treated with AFB₁, while in the same cells causing the decrease in β-catenin expression when treated at their IC₅₀ values. miR-33a, specifically miR-33a-5p, was demonstrated to down-regulate the expression of β-catenin, affect the β-catenin pathway, and inhibit cell growth. …”

Effect of Molecular Structure on the B3LYP-Computed HOMO–LUMO Gap: A Structure −Property Relationship Using Atomic Signatures by Ahmed Mohamed (628889)

“…The atomic fragments containing π-bonds in various aromatic compounds were found to be the most significant atomic Signatures, explaining nearly 50% of the variance in the data, with regression coefficients that decreased <i>E</i>_gap. …”

Table_1_Chemical-Shift-Encoded Magnetic Resonance Imaging and Spectroscopy to Reveal Immediate and Long-Term Multi-Organs Composition Changes of a 14-Days Periodic Fasting Interven... by Magalie Viallon (3140223)

“…Fat fraction, MRI relativity index T2^* and susceptibility (Chi), as well as Fatty acid composition, were calculated at all-time points.</p><p>Results: A decrease in body weight (BW: −9.5%), quadriceps muscle volume (−3.2%), Subcutaneous and Visceral Adipose Tissue (SAT −34.4%; VAT −20.8%), liver fat fraction (PDFF = 1.4 vs. 2.6 % at baseline) but increase in Spine Bone Marrow adipose tissue (BMAT) associated with a 10% increase in global adiposity fraction (PDFF: 54.4 vs. 50.9%) was observed. …”

Fig 3 - by Jianfeng Yang (49036)

Raw EEG data at Fz, Cz, and Pz for preschoolers. by Koji Kashihara (12475877)

Wavelet data at Fz and Pz sites for preschoolers. by Koji Kashihara (12475877)

Raw EEG data at Fz, Cz, and Pz for young adults. by Koji Kashihara (12475877)

Wavelet data at Fz and Pz sites for young adults. by Koji Kashihara (12475877)

Behavioral data for preschoolers and young adults. by Koji Kashihara (12475877)

Capillary Flow Control in Vacuum Drying for Uniform Pixel Thin Films in Inkjet-Printed OLEDs: Effects of Pumping Speed and Binary Solvent Ratios by Youngwook Noh (2629975)

“…As the boiling point of the mixed solvent increased, the vacuum level at the onset of Evaporation II decreased, shortening its lifetime. …”

Capillary Flow Control in Vacuum Drying for Uniform Pixel Thin Films in Inkjet-Printed OLEDs: Effects of Pumping Speed and Binary Solvent Ratios by Youngwook Noh (2629975)

“…As the boiling point of the mixed solvent increased, the vacuum level at the onset of Evaporation II decreased, shortening its lifetime. …”

Capillary Flow Control in Vacuum Drying for Uniform Pixel Thin Films in Inkjet-Printed OLEDs: Effects of Pumping Speed and Binary Solvent Ratios by Youngwook Noh (2629975)

“…As the boiling point of the mixed solvent increased, the vacuum level at the onset of Evaporation II decreased, shortening its lifetime. …”

Capillary Flow Control in Vacuum Drying for Uniform Pixel Thin Films in Inkjet-Printed OLEDs: Effects of Pumping Speed and Binary Solvent Ratios by Youngwook Noh (2629975)

“…As the boiling point of the mixed solvent increased, the vacuum level at the onset of Evaporation II decreased, shortening its lifetime. …”

Characterizing the exposure of the co-receptor binding site by neutralization sensitive Env mutants. by Caio Foulkes (20592250)

Pan-genome accumulation curve of <i>S</i>. Paratyphi. by Sadia Isfat Ara Rahman (8501859)

The local evolutionary history of the pHCM2 plasmid in Bangladesh. by Sadia Isfat Ara Rahman (8501859)

Influence of the order of addition of fusing partners on HCVpp 1a fusion inhibition by Arb. by Elodie Teissier (232354)

“…a<p>Arb (11.3 µM) was pre-incubated sequentially with either HCVpp or R₁₈-labeled liposomes or both for the indicated times at 37°C before initiating lipid mixing by decreasing pH to 5.0 as described in the legend to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015874#pone-0015874-g002" target="_blank">Figure 2</a>. …”