Image_3_Repeated Inoculation of Young Calves With Rumen Microbiota Does Not Significantly Modulate the Rumen Prokaryotic Microbiota Consistently but Decreases Diarrhea.TIF by Dengpan Bu (369549)

Image_5_Repeated Inoculation of Young Calves With Rumen Microbiota Does Not Significantly Modulate the Rumen Prokaryotic Microbiota Consistently but Decreases Diarrhea.TIF by Dengpan Bu (369549)

Image_2_Repeated Inoculation of Young Calves With Rumen Microbiota Does Not Significantly Modulate the Rumen Prokaryotic Microbiota Consistently but Decreases Diarrhea.TIF by Dengpan Bu (369549)

β₂-Agonist Induced cAMP Is Decreased in Asthmatic Airway Smooth Muscle Due to Increased PDE4D by Thomas Trian (221535)

“…</p> <h3>Results</h3><p>In the presence of IBMX, a pan PDE inhibitor, asthmatic ASM had ∼50% lower cAMP production in response to isoproterenol, albuterol, formoterol, and forskolin compared to non-asthmatic ASM. …”

RNA sequencing linkage analysis identifies a single base pair change on Chromosome 25 that is tightly linked to the <i>escapist</i> hypersensitive phenotype. by Elelbin A. Ortiz (8655285)

H-MSCs^WT prevent hypoxia induced cardiac fibroblast activation, but leptin deficit inhibit this effect. by Panpan Chen (307628)

Video example of a boundary vector cell. by Lear Cohen (15353793)

Elimination of the MRC rescues the prophase I delay due to constitutive Rad51 activation, while decreasing spore viability and increasing MI nondisjunction. by Andrew Ziesel (9422868)

Tun impairs alveolarization in NOX neonatal rat lungs. by Kirkwood A. Pritchard Jr. (13449794)

“…The decreased radial alveolar counts (RAC; 2.9±0.5 <i>vs</i> 4.8±0.7, n = 11, 5 males and 5 females each group, p<0.001) (<b>A</b>), increased mean linear intercepts (MLI; 77.8±6.8 μm <i>v</i>.…”

Illustration of the difference between the IC50 value assessed directly from experimental data and model-based deconvolution of mechanisms explaining downstream inhibition. by Jennifer L. Wilson (6061124)

“…In the proposed modeling framework, it is possible to separate effects on a specific cell type, from propagated effects, such as loss of upstream progenitors. …”

Cell cycle accumulation at G2/M in MTDH knockdown Hec50co cells at 24 hours after LBH589 or LBH589 and TRAIL treatment. by Xiangbing Meng (200278)

“…<p>(A) Cell cycle profiles were determined in control or MTDH knockdown Hec50co cells at 24 hours after treatment with 20 nM LBH589, 25 ng/ml TRAIL, or LBH589 and TRAIL in combination. …”

Oxidation of L-[1-¹⁴C]Cys as a percentage of dose in enterally fed piglets receiving graded levels of Cys and 0.25 g kg^-1 d^-1 Met. by Anna K. Shoveller (6208457)

An association between decreasing incidence of invasive non-typhoidal salmonellosis and increased use of antiretroviral therapy, Gauteng Province, South Africa, 2003–2013 by Karen H. Keddy (833179)

“…</p><p>Results</p><p>From 2003–2013, the incidence of iNTS per 100,000 population per year decreased from 5.0 to 2.2 (p < .001). From 2004 to 2013, the incidence per 100,000 population of HIV viral load testing increased from 75.2 to 3,620.3 (p < .001). …”

<i>In vitro</i> drug susceptibility of a panel of recent clinical <i>L</i>. <i>infantum</i> isolates against antileishmanial reference drugs in THP-1, bone-marrow derived macrophag... by Sarah Hendrickx (321143)

Preformed biofilm. by Rodrigo Rollin-Pinheiro (239450)

Biofilm formation. by Rodrigo Rollin-Pinheiro (239450)

Benchmarking the Predictive Power of Ligand Efficiency Indices in QSAR by Isidro Cortes-Ciriano (1450789)

“…Two studies published in this journal showed that higher predictive power on external molecules can be achieved by using ligand efficiency indices as the dependent variable instead of a metric of potency (IC₅₀) or binding affinity (<i>K</i>_<i>i</i>). …”

2‑Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) by Ariel L. Burgio (15069256)

“…Our studies revealed <b>SLB1122168</b> (<b>33p</b>), which is a potent inhibitor (IC₅₀ = 94 ± 6 nM) of Spns2-mediated S1P release. …”

The effect of alexidine, amorolfine and olorofim on <i>S</i>. <i>aurantiacum</i> morphology and cell parameters. by Rodrigo Rollin-Pinheiro (239450)

Genotoxicity of free <i>versus</i> PLGA-adsorbed benzo(a)pyrene. by Rodolphe Carpentier (4357222)