Schematic Diagram for the possible effect of ipriflavone and ipriflavone nanoformulation on LPS brain inflammation induced rats. by Nashwa W. Yassa (9267665)

Is Pethidine Safe during Labor? Systematic Review by Rogevando Rodrigues Nunes (4770603)

“…Methods Systematic review in the Capes Periodicals/PubMed and MEDLINE/Virtual Health Library (BVS, in the Portuguese acronym) databases. Results A total of 17 studies published from January 1st, 2000, to September 2nd, 2016, with a total of 1,688 participants involved were included in the present review. …”

Changes of CB1-R-staining in the acute phase. by Mária R. Karlócai (340337)

“…In the acute phase of epilepsy (2 hours after pilocarpine injection) the hippocampi of strongly epileptic animals show decrease of CB1-R staining (B, D) compared to controls (A, C). …”

Datasheet1_Effect of 10-year cumulative blood pressure exposure on atherosclerotic cardiovascular disease of different age groups: kailuan cohort study.doc by Lu Guo (281252)

“…There was a significant difference in the risk of ASCVD between the age groups, with participants aged <50 years having the highest risk, followed by those aged 50–59, 60–69, and ≥70 years.…”

Spatially Defined InsP₃-Mediated Signaling in Embryonic Stem Cell-Derived Cardiomyocytes by Nidhi Kapoor (290320)

“…A 3.7% and 1.7% increase of FIRE-1 FRET ratio and 3.0 and 1.5 fold increase in beating frequency was recorded upon stimulation with endothelin-1 (ET-1, 100 nmol/L) or phenylephrine (PE, 10 µmol/L), respectively. …”

Developmental dichotomy of CLP1 and presumptive CLP2 progenitor cells evidenced by analysis of Gfi1^−/− and Gfi1^GFP/+ mice. by Chozhavendan Rathinam (273627)

“…The total number of thymocytes was decreased by ∼6 fold in Gfi1^−/− mice. Shown is a representative experiment of 3. …”

<i>lin-4</i> and its targets <i>lin-14</i> and <i>lin-28</i> are expressed reciprocally during larval development. by Katherine Olsson-Carter (244338)

“…*p-value = 0.012. ***p-values<0.001 (2.5×10⁻⁵ for L3 and 6.3×10⁻⁷ for L4). …”

K_eq and Φ of the α subunit. by Pallavi A. Bafna (271514)

“…Φ-values of 55 different residues plotted as a function of sequence position (≥2 mutants and >5-fold range in K_eq). Subunit domains are shown along the x-axis. …”

Differential OTU abundance of anode-attached microbes and reactor microbes between M1L and M2H reactors. by Nattawet Sriwichai (18847466)

“…<p><b>A</b>, Volcano plot demonstrating significantly different OTUs between M1L and M2H using the criteria: a log-transformed FDR < 0.05 and an absolute log₂ fold-change ≥ 5. 74 OTUs are downregulated while 43 OTUs are upregulated in M1L/M2H. …”

Supplementary Material for: High-Throughput Data of Circular RNA Profiles in Human Temporal Cortex Tissue Reveals Novel Insights into Temporal Lobe Epilepsy by Li J. (2831522)

“…Bioinformatic analysis revealed that circ-EFCAB2 binds to miR-485-5p to increase the expression level of the ion channel CLCN6, while circ-DROSHA interacts with miR-1252-5p to decrease the expression level of ATP1A2. …”

DataSheet_1_Glutaredoxin 2 Reduces Asthma-Like Acute Airway Inflammation in Mice.pdf by Eva-Maria Hanschmann (740672)

“…The Grx2 Cys-X-X-Ser mutant that facilitates de-/glutathionylation, but does not catalyze dithiol/disulfide exchange lost the ability to protect from airway hyper reactivity and to decrease NO release by macrophages, however, it reduced the number of infiltrating immune cells and IL-5 release. …”

Serology for Trachoma Surveillance after Cessation of Mass Drug Administration by Diana L. Martin (300642)

“…Among 1–9 year olds, TF prevalence was 6.5%, whereas only 3.5% were seropositive. Force of infection modelling indicated a 10-fold decrease in seroconversion rate at a time corresponding to MDA commencement. …”

AmB-resistant strains critically depend on high levels of Hsp90 function for survival. by Benjamin Matteson Vincent (477570)

“…<p>(A) Mild inhibition of Hsp90 not only reverses AmB resistance but selectively kills AmB-resistant isolates. Spot assays (5-fold serial dilutions) of wild-type (SC5314), fluconazole-resistant (Isolate #2, <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001692#pbio.1001692-White2" target="_blank">[61]</a>), and AmB-resistant (ATCC 200955) <i>C. albicans</i> on RPMI media containing antifungals and/or Hsp90 inhibitors at the indicated concentrations. …”

Excess mortality and hospitalizations in transitional-age youths with a long-term disease: A national population-based cohort study by Antoine Rachas (197007)

“…Their mortality rate between the ages of 14 and 21 years was 20.9/10,000 person-years (13.7–32.1) <i>versus</i> 1.9 (1.5–2.5) for adolescents without a LTD. Mortality was higher in males than females in youths without a LTD, but not in those with a LTD. …”

RAD21 is necessary for ERα binding within the <i>MYC</i> locus but not an exogenous ERE. A) RAD21 silencing abrogates ERα binding upstream of <i>MYC</i>. by Miranda V. McEwan (121381)

“…MCF7 cells were transfected for 48 hours with Control, RAD21 or ESR1 siRNA and either a negative control (NEG) plasmid, a positive control plasmid (POS) or a plasmid encoding the firefly luciferase reporter gene under the control of 5 EREs. Cells were treated with vehicle (V) or estradiol (E) for 24 hours before luciferase activity was measured. …”

A robust intracellular metabolite extraction protocol for human neutrophil metabolic profiling by Susama Chokesuwattanaskul (5813888)

“…Cell number and number of scans (NS) were optimised as >3.6 million cells and 512 NS. 327 spectral bins were defined in the neutrophil spectra, of which 287 (87.7%) were assigned to 110 metabolites that included: amino acids, peptides and analogues; carbohydrates, carbonyls and alcohols; nucleotides, nucleosides and analogues; lipids and lipid-like molecules; benzenoids; and other organic compounds. 43 metabolites changed at least 1.5 fold (increase or decrease) after the addition of PMA for 5 or 15 min. …”

Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools by Jun Ding (80820)

“…Both homoplasmies and heteroplasmies show 5-fold higher transition/transversion ratios than variants in nuclear DNA. …”

Supplementary Material for: Neuronal Nitric Oxide Synthase Inhibition Prevents Cerebral Palsy following Hypoxia-Ischemia in Fetal Rabbits: Comparison between JI-8 and 7-Nitroindazo... by Yu L. (3691228)

“…JI-8 was also significantly superior to saline in preserving smell, muscle tone and righting reflex function, but 7-NI did not show significant improvement. Furthermore, a 100-fold increase in the dose (15.75 µmol/kg) of 7-NI significantly decreased systolic blood pressure in the dam, while JI-8 did not. …”

Image_1_Increased miR-142-3p Expression Might Explain Reduced Regulatory T Cell Function in Granulomatosis With Polyangiitis.JPEG by Gerjan J. Dekkema (7375049)

“…Overexpression of miR-142-3p significantly decreased cAMP levels (p = 0.02) and tended to decrease the mRNA levels of a predicted target gene, adenylate cyclase 9 (ADCY9; p = 0.06). …”

Table_1_Increased miR-142-3p Expression Might Explain Reduced Regulatory T Cell Function in Granulomatosis With Polyangiitis.pdf by Gerjan J. Dekkema (7375049)

“…Overexpression of miR-142-3p significantly decreased cAMP levels (p = 0.02) and tended to decrease the mRNA levels of a predicted target gene, adenylate cyclase 9 (ADCY9; p = 0.06). …”