Image_1_Germinal centers are permissive to subdominant antibody responses.eps by Philippe A. Robert (7350209)

“…Less immunogenic domains reduced the dominance of GC responses to more immunogenic domains, albeit at a later time point.</p>Discussion<p>The simulations suggest that increased vaccine valency may decrease immunodominance of the GC response to strongly immunogenic domains and therefore, act as a potential strategy for the natural induction of broadly neutralizing antibodies in GC reactions.…”

Image_2_Germinal centers are permissive to subdominant antibody responses.eps by Philippe A. Robert (7350209)

“…Less immunogenic domains reduced the dominance of GC responses to more immunogenic domains, albeit at a later time point.</p>Discussion<p>The simulations suggest that increased vaccine valency may decrease immunodominance of the GC response to strongly immunogenic domains and therefore, act as a potential strategy for the natural induction of broadly neutralizing antibodies in GC reactions.…”

DataSheet_1_Germinal centers are permissive to subdominant antibody responses.xlsx by Philippe A. Robert (7350209)

“…Less immunogenic domains reduced the dominance of GC responses to more immunogenic domains, albeit at a later time point.</p>Discussion<p>The simulations suggest that increased vaccine valency may decrease immunodominance of the GC response to strongly immunogenic domains and therefore, act as a potential strategy for the natural induction of broadly neutralizing antibodies in GC reactions.…”

More than two decades after the introduction of Limnoperna fortunei (Dunker 1857) in La Plata Basin by M. A. Pessotto (4770456)

“…Despite maximum density was found near the introduction point (La Plata River) similar value was also observed 2,000 km north (Paraguay River). …”

Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors by Doris A. Schuetz (5202461)

“…We discovered that an increased ligand desolvation barrier by introducing polar substituents resulted in a significant <i>k</i>_on decrease. The slowdown was accomplished by introducing polar moieties to those parts of the ligand that point toward a hydrophobic cavity. …”

Table_1_Germinal centers are permissive to subdominant antibody responses.xlsx by Philippe A. Robert (7350209)

“…Less immunogenic domains reduced the dominance of GC responses to more immunogenic domains, albeit at a later time point.</p>Discussion<p>The simulations suggest that increased vaccine valency may decrease immunodominance of the GC response to strongly immunogenic domains and therefore, act as a potential strategy for the natural induction of broadly neutralizing antibodies in GC reactions.…”

Data_Sheet_1_Differences in the Seed Germination of Leymus chinensis (Poaceae) Ecotypes Reveal Distinct Strategies for Coping With Salinity Stress: A Common Garden Experiment.CSV by Meng-Yao Ma (11434510)

“…As the salinity level increased, the radicle length of the two ecotypes decreased; however, GG had longer radicles and a higher number of radicles, even at 200 mM NaCl when no radicle protruding from the seed coat was detected in YG. …”

Data_Sheet_3_Differences in the Seed Germination of Leymus chinensis (Poaceae) Ecotypes Reveal Distinct Strategies for Coping With Salinity Stress: A Common Garden Experiment.CSV by Meng-Yao Ma (11434510)

“…As the salinity level increased, the radicle length of the two ecotypes decreased; however, GG had longer radicles and a higher number of radicles, even at 200 mM NaCl when no radicle protruding from the seed coat was detected in YG. …”

Data_Sheet_6_Differences in the Seed Germination of Leymus chinensis (Poaceae) Ecotypes Reveal Distinct Strategies for Coping With Salinity Stress: A Common Garden Experiment.CSV by Meng-Yao Ma (11434510)

“…As the salinity level increased, the radicle length of the two ecotypes decreased; however, GG had longer radicles and a higher number of radicles, even at 200 mM NaCl when no radicle protruding from the seed coat was detected in YG. …”

Data_Sheet_2_Differences in the Seed Germination of Leymus chinensis (Poaceae) Ecotypes Reveal Distinct Strategies for Coping With Salinity Stress: A Common Garden Experiment.CSV by Meng-Yao Ma (11434510)

“…As the salinity level increased, the radicle length of the two ecotypes decreased; however, GG had longer radicles and a higher number of radicles, even at 200 mM NaCl when no radicle protruding from the seed coat was detected in YG. …”

Data_Sheet_7_Differences in the Seed Germination of Leymus chinensis (Poaceae) Ecotypes Reveal Distinct Strategies for Coping With Salinity Stress: A Common Garden Experiment.CSV by Meng-Yao Ma (11434510)

“…As the salinity level increased, the radicle length of the two ecotypes decreased; however, GG had longer radicles and a higher number of radicles, even at 200 mM NaCl when no radicle protruding from the seed coat was detected in YG. …”

Data_Sheet_4_Differences in the Seed Germination of Leymus chinensis (Poaceae) Ecotypes Reveal Distinct Strategies for Coping With Salinity Stress: A Common Garden Experiment.CSV by Meng-Yao Ma (11434510)

“…As the salinity level increased, the radicle length of the two ecotypes decreased; however, GG had longer radicles and a higher number of radicles, even at 200 mM NaCl when no radicle protruding from the seed coat was detected in YG. …”

Data_Sheet_5_Differences in the Seed Germination of Leymus chinensis (Poaceae) Ecotypes Reveal Distinct Strategies for Coping With Salinity Stress: A Common Garden Experiment.CSV by Meng-Yao Ma (11434510)

“…As the salinity level increased, the radicle length of the two ecotypes decreased; however, GG had longer radicles and a higher number of radicles, even at 200 mM NaCl when no radicle protruding from the seed coat was detected in YG. …”

Data_Sheet_1_The higher levels of self-reported satisfaction, the lower risk of depressive symptoms: Evidence from a nationwide cross-sectional study in China.docx by Zhiping Niu (9718648)

“…Depressive status was evaluated using the 10-item center for epidemiological studies depression scale (CESD-10), and self-reported life, health, marital status, parent-child relationship, and air quality satisfaction were adopted using Likert 5-point evaluation methods. A generalized linear model (GLM) was applied to explore the association between satisfaction and depression risk.…”

The enhanced radiosensitization of certain cell cultures with combination of 17AAG with inhibitors of the Hsp70 induction. by Vladimir A. Kudryavtsev (3836524)

“…The similarly enhanced radiosensitization was also found in other cell cultures (A549, HT 1080 and Myc-CaP) with 50–200 nM geldanamycin or 30–100 nM radicicol, or 50–200 nM NVP-AUY922 instead of 17AAG and with 100–200 μM KNK437, or 5–20 μM NZ28 instead of quercetin and triptolide (see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173640#pone.0173640.t002" target="_blank">Table 2</a>). …”

DataSheet1_Injectable hydrogel with immobilized BMP-2 mimetic peptide for local bone regeneration.pdf by Kirstene A. Gultian (13136634)

Vector genomes and GFP mRNA in heart and liver. by Bryan A. Piras (314201)

“…The shGFP group showed a 77% reduction in cardiac GFP mRNA compared to the shControl group (n=7/group, p<0.0001), and while the shGFP group showed a 39% decrease in mRNA in liver, the difference was not statistically significant (n=7/group, p=0.38).…”

Determination of the changes in contact area during osmotic stimulation of adhered primary hepatocytes. by Tabea A. Mundinger (124217)

“…The original relative contact area (i) changes considerably during hypoosmotic stimulation (ii) and does not return to its original area afterwards (iii). A rapid decrease in relative contact area can be observed after returning to normoosmotic media (iv) followed by the stabilization of the relative contact area (v). b) All areas defined as relative contact areas in the consensus of both wavelengths are represented here as black areas. …”

Therapeutic efficacy study in <i>E</i>. <i>granulosus</i> infected mice. by Julia A. Loos (737868)

“…<p>(A) Box plots showing the comparative distribution of the weight (g) of cysts recovered from untreated mice (C) and treated with albendazole (ABZ, 5 mg/kg/d), metformin (Met, 50 mg/kg/d) and the combination of both drugs (ABZ+Met) for 60 days. …”

Addition of 2-DG sequesters cholesterol from the cell membrane. by Charles A. Coomer (8479434)

“…<p>A.) Representative images depicting filipin mean fluorescence intensity per cell indicating two-hour incubation of increasing concentrations of 2-DG decreases surface cholesterol in TZM-bl cells; scale bar 50 μm. …”