Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart حسب Amara, Issa E.A.

"…Our results showed that mercury treatment caused a significant induction of the cardiac hypertrophy markers, atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP); in addition to Cyp1a1, Cyp1b1, Cyp2b9, Cyp2b10, Cyp2b19, Cyp2c29, Cyp2c38, Cyp4a10, Cyp4a12, Cyp4a14, Cyp4f13, Cyp4f15, Cyp4f16 and Cyp4f18 gene expression. …"
احصل على النص الكامل
احصل على النص الكامل

Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma حسب Munusamy, Shankar

"…Background and Objectives: Renal cell carcinoma is the most common and lethal form of all renal cancers, and accounts for 4.1% of all cancer cases in Qatar. Mutations to Von-Hippel Lindeau (VHL) gene in renal cells activates hypoxia inducible factor-1 alpha (HIF-1?) …"
احصل على النص الكامل
احصل على النص الكامل

Trilemma of life cycle carbon, employment, and costs of trucking industry's shift toward automation and electrification حسب Mandouri, Jafar

"…Autonomy and electrification combined could lead to a 50% decrease in emissions and 46% savings in life cycle costs. …"
احصل على النص الكامل
احصل على النص الكامل

The Structure of the Free Volume in Poly(styrene-co-acrylonitrile) from Positron Lifetime and Pressure Volume Temperature (PVT) Experiments حسب Dlubek, Gunter

"…The mean hole volume, vh, varies in PS between 105 Å3 (27 °C) and 220 Å3 (190 °C), and shows a systematic decrease with increasing AN content, at Tg from 121 Å3 for PS to 102 (±2) Å3 for SAN50. …"
احصل على النص الكامل
احصل على النص الكامل

Relationship between fat distribution, iron status, and hepcidin in Qatari obese adults حسب Abdelhamid, kerkadi

"…We noted a decrease in ferritin, Hemoglobin, serum iron and RBC with an increase in % fat. …"
احصل على النص الكامل
احصل على النص الكامل

Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro حسب Rizk, Nasser Moustafa

"…In conclusion, this study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours, insulin could counteract the hyperglycemic effect on AKT/pI3 kinase which mediates NO production and VEGF-A, decreased adhesion molecules p-selectin involved in barrier disorder of retinal endothelial cells. …"
احصل على النص الكامل
احصل على النص الكامل

Antibiotic Prescription Patterns for Upper Respiratory Tract Infections in Outpatient Qatari Population in the Private Sector حسب Butt, Adeel Ajwad

"…Results: There were a total of 75,733 claims during the study period. …"
احصل على النص الكامل
احصل على النص الكامل

Developmental Toxicity of Surface-Modified Gold Nanorods in the Zebrafish Model حسب Zakaria, Zain Z

"…Our data showed that AuNRs caused mortality with a calculated LC50 of EC50,24hpf of AuNRs being 9.1 μg/mL, while a higher concentration of AuNRs was revealed to elicit developmental abnormalities. …"
احصل على النص الكامل
احصل على النص الكامل

A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis حسب Tricarico, Paola Maura

"…Focusing on rare damaging variants, we identified a rare insertion of one nucleotide (c.225dupA:p.A76Sfs*21) in the DCD gene encoding for the antimicrobial peptide dermcidin (DCD) that was shared by the proband, his affected father and his 11-years old daughter. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The expression of bile acid Receptor TGR5 in Adipose Tissue in Diet-induced obesity mice حسب Ahmed, Sumaya

"…There was significant downregulation of TGR5 gene expression level in obese (DIO) mice and remarkable upregulation of TGR5 gene expression after successful weight loss in DIO mice treated with SFN in time dependent manner at 1 weeks and 4 weeks of ip applications. …"
احصل على النص الكامل
احصل على النص الكامل

Associations of Recreational and Nonrecreational Physical Activity and Body Weight Change on Cardiovascular Disease Mortality During the Obesogenic Transition in the United States:... حسب Cheema, Birinder S.

"…RESULTS: Compared with the "moderate-vigorous stable" group (reference), individuals who remained inactive ("inactive stable") or reduced their participation in physical activity ("active to inactive") experienced the highest mortality, with a 50% to 176% and 22% to 222% relative increased hazard ratios for nonrecreational and recreational physical activity, respectively, across all models adjusted for covariates. …"
احصل على النص الكامل
احصل على النص الكامل

Evacuated tube heat pipe solar collector for Encontech engine-driven reverse osmosis solar desalination حسب Takalkar, Gorakshnath

"…Further increment in this ratio up to 3 resulted in a decrease in the efficiency of the ETHPSC.…"
احصل على النص الكامل
احصل على النص الكامل

Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey. حسب Wang, Yue

"…Logistic regression was used to examine the association. The mean age of the study population was 50·9 (sd 15·1) years. …"
احصل على النص الكامل
احصل على النص الكامل

Carob (Ceratonia siliqua L.) Prevents Short-Term Memory Deficit Induced by Chronic Stress in Rats حسب Alzoubi K.H.

"…This impairment could be attributed to a decrease in brain-derived neurotrophic factor (BDNF) levels during chronic stress. …"
احصل على النص الكامل
احصل على النص الكامل

Effect of mobile text messages on antiretroviral medication adherence and patient retention in early HIV care: An open-label, randomized, single center study in south Florida حسب Sherman, Elizabeth M.

"…Background People with HIV (PHIV) with limited access to health services often experience suboptimal antiretroviral therapy (ART) adherence. We investigated whether a daily text messaging intervention improves ART adherence and retention in early HIV care in PHIV in a south Florida hospital-based clinic. …"
احصل على النص الكامل
احصل على النص الكامل

Flight Scheduling in the Airspace حسب Msakni, Mohamed Kais

"…The mathematical model has been solved using CPLEX 12.6 and the scatter search has been coded using C language under Microsoft Visual Studio v12 environment. …"
احصل على النص الكامل
احصل على النص الكامل

Nanoclay compatibilization of phase separated polysulfone/polyimide films for oxygen barrier حسب Ammar, Ali

"…Thermal decomposition (TGA) measurements of PSF/PI films showed a decrease in thermal stability upon adding C30B due to its surfactant modification, while film mechanical tensile modulus properties improved slightly by adding low concentration of C30B (~ 1 mass%), but higher nanoclay loading decreased tensile strength and elongation at break. …"
احصل على النص الكامل
احصل على النص الكامل

Heme Oxygenase Isoform 1 Regresses Cardiomyocyte Hypertrophy Through Regressing Sodium Proton Exchanger Isoform 1 Activity حسب Sobh, Ahmed

احصل على النص الكامل
احصل على النص الكامل

Effects of Combined Calcium Hypochlorite and Chlorine Dioxide on Drinking Water Quality in Qatar and Disinfection by Products Formation حسب Mohamed, Elsamoul H.

احصل على النص الكامل
احصل على النص الكامل

Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte. حسب Marei, Hany E

"…In addition, a significant up regulation in gene and protein expression profile of stage specific cell markers for OPCs/OLs (CNPase, Galc, NG2, MOG, OLIG1, OLIG2, MBP), neurons, and astrocytes (MAP2, β-TubulinIII, GFAP) and concomitant decrease of OBNSCs pluripotency markers (Oct4, Sox2, Nestin), was demonstrated following induction of OBNSCs differentiation. …"
احصل على النص الكامل
احصل على النص الكامل