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61
Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Two arginine residues (131 and 203) in the HNF1A protein are highly conserved residues and contribute to the function of the protein. …”
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62
Effects of superelastic nano-NiTi additions on electroless Ni –P coating properties under bending
Published 2019“…In this study, electroless Ni –P-nano-NiTi composite coatings containing 5.14 wt%, 6.07 wt%, and 7.02 wt % NiTi were subjected to three-point bend testing in order to determine bending properties. …”
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63
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
Published 2020“…We investigated the impact of two novel human MYBPC3 splice-site variants: V1: c.654+2_654+4dupTGG targeting exon 5 using morpholino MOe5i5; and V2: c.772+1G'A targeting exon 6 using MOe6i6; located within C1 domain of cMyBP-C protein, known to be critical in regulating sarcomere structure and contractility. …”
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65
Nutritional quality and health risk of pepper fruit as affected by magnesium fertilization.
Published 2020“…Magnesium application increased concentrations of Mg and capsaicinoids, decreased those of calcium (Ca), zinc (Zn) and vitamin C (Vc), and had no effect on potassium (K) and iron (Fe) in pepper fruit. …”
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66
Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents
Published 2023“…Their IC50 values ranged from 1.2 to 9.04 µM for interleukin-6; from 1.5 to 19.3 µM for Chemokine (C-C) Ligand 2; from 2.4 to 5.2 µM for nitric oxide; and from 1.1 to 20.5 µM for prostaglandin E2. …”
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67
Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0M HCl via multi-carbonyl Gemini cationic surfactants
Published 2023“…EIS data suggests the enhancement of the thickness of the adsorbed layers of the studied compounds from the decrease of the double-layer capacitance C dl values. …”
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68
The Formation of Sulfide Scales on Carbon Steel in Saturated H2S
Published 2020“…The electrochemical reaction commonly contains three stages: first, the reactant transported from the solution (bulk) to the metal surface; then the transfer of the charge reaction on the surface, followed by the reaction product transported away from the iron surface to the bulk solution or the formation and development of the corrosion product which then can decrease the corrosion rate. Development of a robust corrosion model to predict the corrosion process in H2S these requires a mechanistic understanding of all these elements. …”
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69
The Formation of Sulfide Scales on Carbon Steel in Saturated H2S
Published 2020“…The electrochemical reaction commonly contains three stages: first, the reactant transported from the solution (bulk) to the metal surface; then the transfer of the charge reaction on the surface, followed by the reaction product transported away from the iron surface to the bulk solution or the formation and development of the corrosion product which then can decrease the corrosion rate. Development of a robust corrosion model to predict the corrosion process in H2S these requires a mechanistic understanding of all these elements. …”
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70
Screening of Qatari Microalgae and Cyanobacteria for Application in CO2 Utilization
Published 2018“…This strain also had the highest nitrogen content (12.2 ± 0.05 % at 40˚C) and carbon content (51.2 ± 0.25 % at 45˚C). …”
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71
In silico and in vivo models for Qatari-Specific classical homocystinuria as basis for development of novel therapies.
Published 2018“…The p.R336C knock-in HEK293T and HepG2 cells decreased the level of CBS expression and reduce its structural stability; however, treatment of the p.R336C knock-in HEK293T cells with betaine, a chemical chaperone, restored the stability and tetrameric conformation of CBS, but not its activity. …”
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72
Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart
Published 2014“…Mercury toxicity was induced by a single intraperitoneal injection (IP) of 2.5mg/kg of mercuric chloride (HgCl2). Our results showed that mercury treatment caused a significant induction of the cardiac hypertrophy markers, atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP); in addition to Cyp1a1, Cyp1b1, Cyp2b9, Cyp2b10, Cyp2b19, Cyp2c29, Cyp2c38, Cyp4a10, Cyp4a12, Cyp4a14, Cyp4f13, Cyp4f15, Cyp4f16 and Cyp4f18 gene expression. …”
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73
Generation, performance evaluation and control design of single-phase differential-mode buck-boost current-source inverters
Published 2016“…Since these inverters have continuous input currents, they are suitable for maximum power point tracking (MPPT) operation of photovoltaic systems. …”
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74
Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy-combustion supercritical CO2 intercooled and reheated cycles under design and off-design condi...
Published 2022“…At off-design conditions with a power demand (PD) of 40% of the design load (50 MW), the thermal efficiency is decreased by 21.82% in DRC, 17.71% in ICC, 22.46% in PIC, and 13.60% in RHC. …”
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75
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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76
An Experimental and Kinetic Study of the Sorption of Carbon Dioxide onto Amine-Treated Oil Fly Ash
Published 2016“…A kinetics study showed that the CO2 adsorption capacity of OFA increased with increasing CO2 flow rates and concentrations and decreasing the relative humidity. …”
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77
Synthesis of silica supported ni and cu catalyst for carbon dioxide methanation reaction
Published 2019“…In this study we investigate the synthesis of nickel and copper catalyst supported on silica for CO2 conversion to methane. The activity and product selectivity and stability for methanation reaction on Ni/SiO2 and Cu/SiO2 catalysts have been evaluated using a flow reactor between 50ºC - 650ºC. …”
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78
The influence of environmental and core temperature on cyclooxygenase and PGE2 in healthy humans
Published 2021“…Random coefficient models determined relationships between Tc and COX/PGE2. Tc [mean (range)] increased in hot [+ 0.8 (0.4–1.2) °C; p < 0.0001; effect size (ES): 2.9], decreased in cold [− 0.5 (− 0.8 to − 0.2) °C; p < 0.0001; ES 2.6] and was unchanged in thermoneutral [+ 0.1 (− 0.2 to 0.4) °C; p = 0.3502]. …”
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79
Study of the Ion Interclation Mechanism in Mxene Membrane for the Water Treatment Applications
Published 2020“…Unfortunately, these membranes can swell and shrink when in contact with water or under high temperatures. MXene (Ti3C2) is a two-dimensional early transition metal carbide-derived by the etching of MAX (Ti3AlC2) phases in fluoride-containing solutions, and it can be intercalated with cations due to its surface termination that makes MXene sheets Negatively charged. …”
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80
Acute and chronic toxicity assessments of 17β-estradiol (E2) and 17α-ethinylestradiol (EE2) on the calanoid copepod Acartia clausi: Effects on survival, development, sex-ratio and...
Published 2022“…Estrogens, such as the 17β-estradiol (E2) and the 17α-ethinylestradiol (EE2), have been regarded as a global threat to aquatic ecosystems due to their pseudo-persistence, their high estrogenic activity and their toxicity towards non-target species. …”
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