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41
Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”
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42
The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy
Published 2014“…Recently, Transgenic mice expressing active-NHE1 demonstrated a>1500-fold increase in osteopontin (OPN) gene expression. …”
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Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells.
Published 2024“…Hypoxia increased HIF1a gene expression by approximately 30% (P<0.01). …”
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44
Profiling of the Differentially Expressed Genes of Inflammation and Angiogenesis of Human Brain Microvascular Endothelial Cells Evoked by Cell Injury In-Vitro to Mimic Acute Ischem...
Published 2020“…RNA extracted was analyzed using RT-PCR profiling of angiogenesis and inflammatory genes, differentially expressed genes were analyzed by Gene Globe analysis, and signaling pathways were identified using IPA software, Qiagen. …”
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45
Two-stage cultivation of a Nannochloropsis mutant for biodiesel feedstock
Published 2015“…Culture was based on photoautotrophic biomass production (stage 1) followed by a switch to photomixotrophic growth induced by adding sodium acetate (2�mM) (stage 2). The biomass yield of the mutant in two-stage cultivation was maintained at a level similar to that of the one-stage photoautotrophic culture, but TFA content was increased by 2.3-fold. …”
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46
Monovalent Anion Interaction on the Electron Flow of Photosystem II in Soyabean Cells
Published 1994“…Increasing the incubation time up to 3 hours decreased the restoration to 43%. Thus, exposing the cells to N2 gas in the absence of the inhibitory anions caused an irreversible damage of photosystem II reflected by the linear electron transport from H2O to DMQ. …”
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Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes
Published 2022“…Furthermore, DHA-treatment of hypoxic cells caused significant reductions in the expression of genes related to hypoxia (HIF-1, HIF-2), anaerobic metabolism (GLUT1 and Ldha), ATP production (ANT2), and fat metabolism (FASN and PPARY). …”
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50
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
Published 2018“…There are two main EBV genotypes, Type 1 and 2, distinguished by the differences in the EBNA-2 gene. …”
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Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia
Published 2016“…Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the mitochondria of red blood cell precursors. …”
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54
Performance and computational studies of two soluble pyran derivatives as corrosion inhibitors for mild steel in HCl
Published 2019“…The inhibition efficiencies increase with increase in concentration and decreases with temperature. The maximum inhibition efficiency was found 90% and 85.4% at 298 K in the presence of 1 mM of DMPHP and HMQP respectively. …”
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55
Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events
Published 2021“…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …”
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Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase
Published 2018“…Furthermore, the overexpression of active NHE1 elicited modulation of gene expression in cardiomyocytes including an upregulation of myocardial osteopontin (OPN) expression. …”
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The effects of oxygen concentration on in vitro output of prostaglandin E2 and interleukin-6 from human fetal membranes.
Published 2007“…In this study, we have investigated the effect of oxygen tension on fetal membrane biology, as a reconsideration of the literature suggests that fetal membranes are normally exposed to approximately 3% O(2) (approximately 20 mmHg) in vivo, rather than the 20% O(2) (150 mmHg) used for in vitro culture. …”
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
Published 2021“…In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression. …”
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Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling.
Published 2019“…SNG treatment of MM cells resulted in a dose-dependent decrease in cell viability through mitochondrial membrane potential loss and activation of caspase 3, 9, and cleavage of PARP. …”
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