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mGluR5 receptor decreased glycinergic currents.
Published 2019“…(<b>E</b>) The inhibitory effect of CHPG on GlyR-IPSCs was not blocked by intracellularly loaded GDP-β-S (62.3 ± 6.4% of baseline at 15–20 min post-CHPG, <i>t</i>[6] = 2.782, <i>p</i> = 0.032), chelerythrine (60.9 ± 11.3% of baseline at 15–20 min post-CHPG, <i>t</i>[6] = 2.705, <i>p</i> = 0.035), or Ro-32-0432 (69.9 ± 3.2% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 8.495, <i>p</i> < 0.001). (<b>F</b>) Postsynaptic loading of U-0126 or PD98059 prevented CHPG from decreasing glycinergic responses (U-0126, 107.6 ± 10.4% of baseline at 15–20 min post-CHPG, <i>t</i>[8] = 0.997, <i>p</i> = 0.348; PD98059, 93.1 ± 5.0% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 0.883, <i>p</i> = 0.418). …”
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Average nearest neighbour analysis before and after filtering of data points.
Published 2022Subjects: -
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Response of small airway tissues infected with EV-D94 and decreasing doses of EV-D68.
Published 2022“…<p>Tissues were infected with 1E7 RNA copies of EV-D94 (equivalent to 2,46E4 TCID50) and 1E7 RNA copies of EV-D68 (3,3E5 TCID50) as well as decreasing doses of the latter. …”
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HPx1 expression is controlled by dietary heme and the E75 transcription factor.
Published 2023Subjects: -
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FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma.
Published 2019“…The mean ± SEM for each treatment group were calculated and depicted in a bar graph. …”
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34
Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons.
Published 2025“…<b>F</b>. Example image of a biocytin-labeled PFC PV interneuron from a control mouse (left) and from cuprizone-treated mouse (right); scale bar: 50 µm. …”
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Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis.
Published 2021“…(<b>H</b>) Quantification of autoradiography for labeled TAG was by ImageJ. <i>n =</i> 5, data are mean ± SD. *<i>p</i> < 0.05. Uncropped western blots are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s016" target="_blank">S1 Raw Images</a>, and numerical data for all graphs are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s014" target="_blank">S6 Data</a>. …”
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Repetitive stress induces a decrease in sound-evoked activity.
Published 2025“…These mice exhibited a minimal change in noise-evoked PPy activity when comparing the first and second week of imaging (2-way ANOVA, F = 1.79, <i>p</i> = 0.11, post hoc baseline w1 50 dB: baseline w2 50 dB <i>p</i> = 1 Bonferroni corrected, nested ANOVA (mouse nested within session) F = 1.76, <i>p</i> = 0.12, mean ± SE). …”