Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia by Kuttikrishnan S.

“…Sang treatment also reduced the phosphorylation of AKT and suppressed the expression of a number of anti-apoptotic genes such as cIAP1, cIAP2, and XIAP. …”
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Clinical significance of P-class pumps in cancer (Review) by Themistocleous, Sophia C.

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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Contrasting cardiovascular mortality trends in Eastern Mediterranean populations: Contributions from risk factor changes and treatments by Critchley, Julia

“…Results Risk factor trends: Smoking prevalence was high in men, persisting in Syria but decreasing in Tunisia, oPt and Turkey. BMI rose by 1-2 kg/m2 and diabetes prevalence increased by 40%-50%. …”
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Investigation of the rheological properties of nanosilica-reinforced polyacrylamide/polyethyleneimine gels for wellbore strengthening at high reservoir temperatures by Shamlooh M.

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Energy Demand Estimation and Forecasting in Qatar by Khalifa, Ahmed Ali

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Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase by Abdulrahman N.

“…The Na+/H+ exchanger isoform 1 (NHE1), a multifunctional protein and the key pH regulator in the heart, has been demonstrated to be increased in this condition. …”
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Binding energy, structural, and dielectric properties of thin film of poly(aniline-co-m-fluoroaniline) by Waware, Umesh S.

“…The permittivity of copolymer PA-co-m-FA50 has a higher value than polyaniline in the high-frequency regime and decreases with the increase of frequency. …”
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Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats by Sayadi, Sami

“…Equally, it showed a rise of the apoptotic markers (a decrease in the expression of the Bcl-2 and an increase of the P53). …”
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Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO2- saturated saline solution by Jalab, Rem

“…Lastly, potentiostatic testing of steel with AGGPAM at an applied potential of 50 mV illustrated surface protection and decreased current over a prolonged time. …”
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Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia by Fernández-Murray1, J. Pedro

“…A common subtype of congenital sideroblastic anemia is due to autosomal recessive mutations in the SLC25A38 gene. …”
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Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel by Ben Ali, Ahmed

“…The effects of various material compositions and reservoir environments on the ultimate strength and swelling kinetics of a commercial preformed particle gel (PPG) have been investigated. …”
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Natural aging of shape stabilized phase change materials based on paraffin wax by Krupa, Igor

“…The addition of 15 wt% of EG to shape stabilized phase change materials (SSPCMs) containing 50 wt% of wax caused a decreasing in the leakage of wax by 50% over 210 days of natural aging. …”
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The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculatio... by Zakaria, El Rasheid

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Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome. by Thirumal Kumar, D

“…This study is expected to serve as a platform for developing targeted drug therapy for BS.…”
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Awareness of disabilities in pharmacy program recruitment material: are we doing enough? by Hussain, Farhat Naz

“…Introduction: Targeted recruitment of students with disabilities is a novel area in pharmacy education and may help to attract qualified students in light of decreasing applicant numbers. …”
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Mechanical and physical behavior of newly developed functionally graded materials and composites of stainless steel 316L with calcium silicate and hydroxyapatite by Ataollahi Oshkour, Azim

“…Compressive mechanical properties of SS-316L/HA decreased sharply with increasing of HA content up to 20. wt% and gradually with CS content up to 50. wt% for SS-316L/CS composites. …”
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Improving mechanical, thermal and damping properties of niti (Nitinol) reinforced aluminum nanocomposites by Matli, Penchal R.

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Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway by Hadrich, F.

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Biodegradable thermoplastic polyurethane composites as potential plating systems in pediatric facial fractures by ALANI, AYA AHMED

“…Due to the rapid growth of facial bone in the pediatric age group, the use of metallic plates would require a second surgical intervention to remove it. The alternative is biodegradable plating systems which are safe but not without complications, including learning curve, decreased stability, cost, and infection. …”
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