Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer by Ashour, Amal

“…Results In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. …”
Get full text
Get full text

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

Get full text
Get full text
Get full text

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

Get full text
Get full text
Get full text

Qatar Culture Collection of Microalgae: A Sustainable Source for Biodiesel Production and Omega Fatty Acid Compounds by Bounnit, Touria

“…A one step transesterification process was used to derivitize the intrinsic lipid into fatty acid methyl esters and the individual components were identified against known standards. …”
Get full text
Get full text

Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects by Alsaad A.M.

“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
Get full text
Get full text

Box-Behnken approach for optimization of Cr(III) removal from a real tanning effluent using powdered marble by Boujelben, R.

“…Microtoxicity (Escherichia coli) assays showed a decrease in the growth inhibition percentage going from 100 to 31% following the adsorption experiment using raw tanning effluent. …”
Get full text
Get full text

Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events by Raj, K. Diraviya

“…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …”
Get full text
Get full text

Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... by Alhujaily, Muhanad

“…High expression of Glo1 contributes to multidrug resistance by shielding the spliceosome from MG modification and decreasing survival in the chemotherapy of breast cancer. …”
Get full text
Get full text
Get full text

Umbelliferone inhibits spermatogenic defects and testicular injury in lead-intoxicated rats by suppressing oxidative stress and inflammation, and improving Nrf2/HO-1 signaling by Alotaibi, Mohammed F.

“…Materials and Methods: Rats received lead acetate (50 mg/kg) and UMB (25, 50 or 100 mg/kg) via oral gavage for 4 weeks. …”
Get full text
Get full text
Get full text

MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS by Hourani, Shireen Bayan

“…Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. …”
Get full text

Accelerated weathering effects on poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and PHBV/TiO2 nanocomposites by Antunes, A.

“…It also slowed down the decrease in mechanical properties. The mechanical properties were shown to gradually decrease for the PHBV/TiO2 nanocomposites, whereas a sharp drop was observed for the neat PHBV after an accelerated weathering exposure. …”
Get full text
Get full text

In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway by Kuttikrishnan, Shilpa

Get full text
Get full text

Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. by Sara, Sokary

“…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …”
Get full text
Get full text
Get full text

Effects of rutile-TiO2 nanoparticles on accelerated weathering degradation of poly(Lactic Acid) by Antunes, A.

“…Thermal stability decreased in the presence of TiO2 and a double melting peak was observed for the PLA/TiO2 nanocomposite. …”
Get full text
Get full text

Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway by Hadrich, F.

“…In preadipocytes cells, EE 1/100 decreased cell viability and induced apoptosis. …”
Get full text
Get full text

Chronic melatonin treatment improves obesity by inducing uncoupling of skeletal muscle SERCA-SLN mediated by CaMKII/AMPK/PGC1α pathway and mitochondrial biogenesis in female and ma... by Salagre, D.

“…Obese ZDF rats and lean littermates (ZL) of both sexes were subdivided into two subgroups: control (C) and 12 weeks orally melatonin treated (M) (10 mg/kg/day). Compared to the control groups, melatonin decreased the body weight gain and visceral fat in ZDF rats of both sexes. …”
Get full text
Get full text

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... by Thirumal Kumar, D

“…We also performed a virtual screening analysis with 19 AKT inhibitors obtained from the Selleck Chemicals website those satisfied the Lipinski rule of 5. …”
Get full text
Get full text

A novel index based on planktonic copepod reproductive traits as a tool for marine ecotoxicology studies by Mohamed Bakr, Hussain

“…At high concentrations, cadmium and silver induce an increase in EPR in the copepods Acartia tonsa and Acartia hudsonica, while exposure to mercury decreases EPR in adults by 50%. All three metals affect HS, with mercury inducing a stronger effect than cadmium and silver. …”
Get full text
Get full text
Get full text

A process for CO2 capture and brine salinity reduction through reaction with potassium hydroxide: A multi-stage evaluation by Mourad, Aya A-H.

“…In the third method, the recovery of Ca2+ and Mg2+ was approximately 76.3% and 94.6%, respectively, following the pre-treatment step (filtration), followed by the same stages as in the second method. …”
Get full text
Get full text

Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit by Al-Sulaiti, Fatima Khalifa

“…Objective: This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar. Methods: A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. …”
Get full text
Get full text
Get full text