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741
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742
Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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743
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744
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746
Intercalation of ionic liquids into bentonite: Swelling and rheological behaviors
Published 2016“…The results from particle sizes and Zeta potential measurements have shown that bentonite intercalated with IL-1 and IL-2 are the most effective in decreasing the overall repulsive forces and increasing the attractive forces on the bentonite surface. …”
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747
Production and Determination of Bioavailable Iron in Sorghum and White bean Noodles
Published 2014“…Results of the study showed that the content of white bean in the noodles had a direct influence on the iron content and bioavailability. …”
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748
Effect of Hydrothermal Carbonization Parameters and Performance of Carbon Dioxide Adsorption on Pineapple Peel Waste Biochar
Published 2022“…The CO2 adsorption capacity of this system was improved with increasing CO2 feed concentration and decreased with rising temperature and feed flow rate. …”
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749
Umbelliferone inhibits spermatogenic defects and testicular injury in lead-intoxicated rats by suppressing oxidative stress and inflammation, and improving Nrf2/HO-1 signaling
Published 2020“…Materials and Methods: Rats received lead acetate (50 mg/kg) and UMB (25, 50 or 100 mg/kg) via oral gavage for 4 weeks. …”
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750
Immunomodulatory Effects of Vitamin D in Pregnancy and Beyond.
Published 2019“…In addition to its role in calcium homeostasis and bone formation, a modulatory role of the active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been described. …”
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751
Phytochemicals as Micronutrients: What Is their Therapeutic Promise in the Management of Traumatic Brain Injury?
Published 2022“…In this regards, phytochemicals have been acknowledged to cause a significant decrease in neuronal injury through different mechanisms including the activation of the Nrf2 transcription factor leading to activation of several antioxidant enzyme systems such as superoxide dismutase, inhibition of NADPH oxidases (NOX) enzymes, suppression of nuclear factor kappa B (NF-κB) activity and reduction of the release of inflammatory mediators, suppression of the NLRP3 inflammasome, stimulation of neurogenesis by activating neurotrophic factors (BDNF), among others. …”
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752
Adaptative Network Topology for Data Centers
Published 2016“…Furthermore, VacoNet reduced the infrastructure cost by about 50%, and the power consumption will be decreased with more than 50000 watt compared to all the previous architectures. …”
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753
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754
Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties
Published 2022“…It is found that the optimal ferroelectric and piezoelectric values were obtained at 1150 °C (P r = 27 µC/cm 2 , E c = 3.89 kV/mm and d 33 = 110 pC/N). According to these results, we suggest that 850 °C and 1150 °C can be considered as optimal calcination and sintering temperature in NBT-6BT ceramic, respectively.…”
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755
Internal Pressure Capacity and Bending Behavior of Glass Fiber Reinforced Composite Overwrapping PVC Plastic Pipes.
Published 2020“…Therefore, this study proposes a glass fiber-reinforced polymer (GFRP) overwrapped system to strengthen the external surface of PVC pipes, which will improve pipes pressure and flexural capacities. …”
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756
Inhibitory effect of sodium nitrite on corrosion of lead in 0.1 M sodium hydroxide solution
Published 1988“…The maximum inhibition efficiency is found to be 49.4% at 35°C and 45.9% at 50°C.…”
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757
A Modular Multilevel Voltage-Boosting Marx Pulse-Waveform Generator for Electroporation Applications
Published 2019“…In the BMPG, a controllable, low-voltage input boost converter supplies, via directing/blocking (D/B) diodes, two arms of a series modular multilevel converter half-bridge sub-modules (HB-SMs). …”
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758
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759
Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media
Published 2021“…As the nanocomposite concentration was increased from 50 to 500 µg/mL, the specific sulfate reduction rate (SSRR) decreased from 0.278 to 0.036 g-sulfate/g-VSS*day showing a relative sulfate reduction inhibition of 86.64% as compared to that of control. …”
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760