Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain حسب Mohammad H., Merii

"…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …"
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…Breast cancer (BC) is the most commonly diagnosed cancer among females worldwide, and among the BC-associated mutations in various proteins, mutations in the RAC-alpha serine/threonine-protein kinase (AKT1) remain the most dominant. We thus attempted to understand the potential molecular pathogenicity profile of the mutations in AKT1 using a comprehensive computational protocol involving analyses of biochemistry-disruption and destabilizing properties and conservation. …"
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A Reconfigurable Multipurpose SoC Mobile Platform for metal detection حسب Al Rshid Abazeed, Omran

"…The electronics components is attached to this arm to the nearest possible point to the coil. The metal detection module attached to a plastic arm and then to the robot. the metal detection module and the spider robot is shown in Fig. 3 and 4 respectively. …"
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Implementing and Analyzing a Recursive Technique for Building Path Oblivious RAM حسب Rachid, Maan Haj

"…When a specific item is requested, a position map is used to point out the leaf to which the block is mapped. …"
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Effects of superelastic nano-NiTi additions on electroless Ni –P coating properties under bending حسب MacLean M.

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Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells. حسب Al-Jaber, Hend

"…Additionally, insulin signaling was examined using the Bio-plex Pro cell signaling Akt panel. We induced insulin resistance in 3T3-L1 cells using IL-6, TNFα, 4HNE, and high insulin in both hypoxic and normoxic conditions. …"
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SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle حسب Koltai, Erika

"…Furthermore, increased levels of K63 and muscle RING finger 2 (MuRF2) protein could also be important enhancers of muscle mass. We report here that the levels of miR1 and miR133a decrease in hypertrophy and negatively correlate with muscle mass, SIRT1 and Nampt levels. …"
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Generation, performance evaluation and control design of single-phase differential-mode buck-boost current-source inverters حسب Darwish, Ahmed

"…Yet, the investigation, operation and implementation of these types of inverters have not been extensively discussed. As a drawback, the total dc side input current of a single-phase inverter consists of a dc component and an undesirable ac component. …"
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Textile-Reinforced Mortar (TRM) System as a Strengthening Technique on Reinforced Concrete Beams حسب Afzal, Muhammad Shekaib

"…The RC beam specimens were tested in flexure under four point loading until failure with a clear span of 2.2 m. …"
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THE ROLE OF QATAR COMMUNITY PHARMACISTS IN DEPRESSION CARE: A SURVEY OF ATTITUDES, PRACTICES AND PERCEIVED BARRIERS حسب SHAMI, RULA

"…Responses were measured on a 5-point-Likert scale. Study outcomes were scores of attitudes to depression, scores of self-reported depression care practices and the number of perceived barriers. …"
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Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update حسب Smatti, Maria K.

"…Here, we provide a review of the EBV epidemiology and the genetic variability of the oncogene LMP-1. …"
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Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer حسب Ashour, Amal

"…Results In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. …"
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Environment Degradation and Economic Growth in the Qatar Economy: Evidence from a Markov Switching Equilibrium Correction Model حسب Charfeddine, Lanouar

"…From the economic perspective, this means that initially economic growth increases environment degradation and then declines it after a threshold point of income per capita. …"
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Aqueous Extract Of Origanum Syriacum Inhibits Proliferation, Migration, Adhesion As Well As Erk1/2 Phosphorylation In Aggressive Breast Cancer حسب Al Kahlout, Amal

"…Moreover, preliminary results indicate that OSE decreased ERK1/2 phosphorylation in MDA-MB-231 cells. …"
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

"…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
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Characterization of polysulfone/diisopropylamine 1-alkyl-3-methylimidazolium ionic liquid membranes: high pressure gas separation applications حسب Khraisheh M.

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Cry1Ac toxicity enhancement towards lepidopteran pest Ephestia kuehniella through its protection against excessive proteolysis حسب Elleuch, Jihen

"…However, a protection against excessive degradation of protoxin and toxin forms of Cry1Ac was strongly decreased in the case of δ-endotoxins produced in the presence of P20 as compared to those from P20 lacking control. …"
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Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events حسب Raj, K. Diraviya

"…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …"
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Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase حسب Abdulrahman N.

"…We have previously demonstrated that elevated NHE1 activity induced cardiac hypertrophy in vivo. …"
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Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart حسب Akhtar, Saghir

"…Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and surface chemistry (-NH2, -COOH and -OH) on cardiac function in mammalian hearts following ischemia-reperfusion (I/R) injury, and (b) determined if any PAMAM-induced cardiotoxicity could be mitigated by Angiotensin-(1-7) (Ang-(1-7), a cardioprotective agent. …"
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