CTNS protein and mRNA levels in human fibroblasts. by Emma J. Brasell (8081969)

Anisotropic Tuning of Graphite Thermal Conductivity by Lithium Intercalation by Xin Qian (714942)

“…We found that intercalation of lithium has an anisotropic effect on tuning the thermal conductivity: the thermal conductivity in the basal plane decreases monotonically from 1232 W/m·K of pristine graphite to 444 W/m·K of the fully lithiated LiC₆, while the thermal conductivity along the <i>c</i>-axis decreases first from 6.5 W/m·K for graphite to 1.3 W/m·K for LiC₁₈ and then increases to 5.0 W/m·K for LiC₆ as the lithium composition increases. …”

Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma by Bo Li (112195)

“…Herein, we report the structure-guided development of a series of covalent inhibitors of FAK. These new compounds displayed highly potent inhibitory potency against FAK enzymatic activity with IC₅₀ values in the nanomolar range. …”

The productivity of a research unit as a function of the funding <i>x</i>. by Miguel Navascués (164739)

Dung Beetles along a Tropical Altitudinal Gradient: Environmental Filtering on Taxonomic and Functional Diversity by Cássio Alencar Nunes (2852327)

“…The altitudinal gradient ranged from 800 up to 1400 m a.s.l. and we collected dung beetles at every 100 m of altitude. …”

Presentation1_The impact of Climate Change on extreme winds over northern Europe according to CMIP6.pdf by Xiaoli Guo Larsén (12502987)

“…We obtain the possible effect of climate change through the comparison of the extreme wind parameters, including the 50-year wind and the 95%-percentile of the wind speed, and the change in turbine class at 50 m, 100 m and 200 m, between a near future period (2020–2049) and the historic period (1980–2009). …”

High blood glucose levels in rats after exposure to STZ. by Shatw Khalid Ali (13020885)

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease by Mercedes Rubio-Hernández (20036142)

“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)­ethylidene)­hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”

Validation of NUMB as a target for <i>miR-146a</i>. by Pei-Shi Hung (489732)

The effects of metformin, donepezil, insulin glargine, and glibenclamide on brain biomarkers: Amyloid β 42, nitric oxide, acetylcholinesterase, malondialdehyde, β secretase, and pM... by Shatw Khalid Ali (13020885)

Anti-inflammatory Meroterpenoids from <i>Baeckea frutescens</i> by Ji-Qin Hou (3642946)

“…Compound <b>8</b> exhibited anti-inflammatory activity with an IC₅₀ value of 0.36 μM, which might be related to the regulation of the NF-κB signaling pathway via the suppression of p65 nuclear translocation and the consequent decrease of IL-6 and TNF-α.…”

Anti-inflammatory Meroterpenoids from <i>Baeckea frutescens</i> by Ji-Qin Hou (3642946)

“…Compound <b>8</b> exhibited anti-inflammatory activity with an IC₅₀ value of 0.36 μM, which might be related to the regulation of the NF-κB signaling pathway via the suppression of p65 nuclear translocation and the consequent decrease of IL-6 and TNF-α.…”

Anti-inflammatory Meroterpenoids from <i>Baeckea frutescens</i> by Ji-Qin Hou (3642946)

“…Compound <b>8</b> exhibited anti-inflammatory activity with an IC₅₀ value of 0.36 μM, which might be related to the regulation of the NF-κB signaling pathway via the suppression of p65 nuclear translocation and the consequent decrease of IL-6 and TNF-α.…”

Potent 5‑Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1–UBE2M Interaction by Wenjuan Zhou (115285)

“…After finding a novel inhibitor <b>DC-1</b> with IC₅₀ = 1.2 μM, we performed a series of chemical optimizations, which finally led to the discovery of a potent thiazole containing 5-cyano-6-phenylpyrimidin-based inhibitor <b>DC-2</b> (IC₅₀ = 15 nM). …”

Image_1_Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.TIFF by Wenfei Xia (5055482)

A trial of seven footfalls in which the subject (emu) underwent a gradual deceleration. by P. J. Bishop (4219759)

Linear stability of the flow of a second order fluid past a wedge by Martina Cracco (19655263)

Activity of miR-124 and miR-23a in NSC-derived neurons and astrocytes. by Annalisa Lattanzi (427545)

“…(B–E) A significant decrease of GFP expression is observed in bdLV.miRT124-transduced neurons (βtubIII, MAP2) (<b>B, C</b>) and in bdLV.miRT23a-transduced astrocytes (GFAP) and immature glial cells (nestin) (<b>D, E</b>). …”

The effect of glibenclamide on channel activity at +20, 0 and -20 mV. by Sajjad Salari (736104)

“…Histogram bars show current amplitudes and P_o of reconstituted channels in absence or presence of glibenclamide. The addition of 50 μM glibenclamide resulted in a decreased current jump amplitude and a reduction in P_o. 100 μM glibenclamide caused a total channel inhibition at +20 and 0 mV (n = 5), but was ineffective at -20 mV. …”