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6181
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6183
DataSheet_1_Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells.pdf
Published 2021“…Herein, we report that such TSLP-induced Th2-type immune response can be effectively controlled by Dectin-1, a C-type lectin receptor expressed by mDCs. Dectin-1 stimulation induced STAT3 activation and decreased the transcriptional activity of p50-RelB, both of which resulted in reduced OX40L expression on TSLP-activated mDCs. …”
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6184
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6185
Medium-Ring Keto Bislactams with Antischistosomal Activity
Published 2024“…Aryl substitution with EWG functional groups decreased the chemical stability. These compounds were relatively polar with the measured LogD<sub>7.4</sub> values ranging from <0 to 2.4, had kinetic aqueous solubilities between 40 and >320 μM, and had relatively low cytotoxicities with IC<sub>50s</sub> ranging from 52 to >390 μM. …”
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6186
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6188
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6189
Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant <i>S. aureus</i> (MRSA) Infections by Targeting Diapop...
Published 2016“…In this research, we developed a series of effective benzocycloalkane-derived CrtN inhibitors with submicromolar IC<sub>50</sub>. …”
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6190
All vaccinated groups have cross-reactive antibodies in their sera against spike proteins of wild type, B.1.1.7, B.1.351, and P.1.
Published 2021“…Binding is shown as AUC, and the differences in binding are indicated by horizontal bars with the calculated fold increase or decrease. Statistical significance was tested with an ANOVA corrected for multiple comparisons. …”
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6191
Inhibition of <i>in vitro</i> and <i>in vivo</i> inflammatory responses in rats by p30A peptide.
Published 2013“…Cell supernatants were collected 48 h later and nitrite levels were quantified. Values are mean±s.d. of cells from 3 different rats. (B) Cumulative clinical score/rat obtained following 50 days post-immunization in all groups. …”
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6192
Image_2_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Cri...
Published 2019“…There was only a marginal increase in the number of EBIMØ after burn, but, between the signatures of EBIMØ, Siglec-1 expression (MFI) was reduced by 40% in B with and a parallel 44% decrease in TBM erythrons in the BM. There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”
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6193
Image_1_A Shift in Myeloid Cell Phenotype via Down Regulation of Siglec-1 in Island Macrophages of Bone Marrow Is Associated With Decreased Late Erythroblasts Seen in Anemia of Cri...
Published 2019“…There was only a marginal increase in the number of EBIMØ after burn, but, between the signatures of EBIMØ, Siglec-1 expression (MFI) was reduced by 40% in B with and a parallel 44% decrease in TBM erythrons in the BM. There were more (2.5-fold) EEBs and less LEBs (2.4-fold) per million TBM cells in B; with a corresponding decrease in Siglec-1 and Ly6G expressions in EBIMØ associated with EEB. …”
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6194
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6195
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6196
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6197
Inhibition of IL-6 Signaling Pathway by Curcumin in Uterine Decidual Cells
Published 2015“…<div><p>IL-6 is a multifunctional pro-inflammatory cytokine and has been implicated in many gestational disorders including preterm birth. …”
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6198
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6199
Density Functional Study on Compounds to Accelerate the Electron Capture Decay of <sup>7</sup>Be
Published 2021“…Thus, the decay can be accelerated by changing the chemical or physical conditions. A previous study reported a 1.1–1.5% reduction in the half-life of <sup>7</sup>Be encapsulated in C<sub>60</sub> compared with <sup>7</sup>Be metal. …”
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6200