Showing 7,221 - 7,240 results of 32,373 for search '(( 50 ((mean decrease) OR (a decrease)) ) OR ( 5 ((fold decrease) OR (nn decrease)) ))', query time: 1.06s Refine Results
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    Nakasone. AJP supple Table1, 2, 3 by Toru Aizawa (9001298)

    Published 2023
    “…<em>Hazard ratio and 95%CI of HGI and HbA1c to incident CKD</em></p> <p>  </p> <p>The data was obtained in Aizawa cohort, in which QR of HGI and HbA1c was almost the same as 0.48 and 0.50 (Table 1) so that scaling was omitted. …”
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    Effects of siRNA-K<sub>v</sub>3.3 transfection on cell adhesion. by Min Seok Song (2153389)

    Published 2016
    “…(E) Cells cultured in fibronectin-coated wells showed amplified effects of decreased K<sub>v</sub>3.3 on integrin β3 levels. The mRNA and protein expression levels of integrin β3 in siRNA-K<sub>v</sub>3.3-transfected cells increased much more during hemin-induced K562 cell erythroid differentiation than in the control group (*p<0.05). …”
  10. 7230

    Image_5_Phylogenetic and functional analysis of tiller angle control homeologs in allotetraploid cotton.tif by Foster Kangben (17875214)

    Published 2024
    “…CRISPR-mediated loss of these TAC1 homeologous genes resulted in a reduction in branch angle and altered petiole angles, and a 5 to 10-fold reduction in TAC1 expression in the mutants, confirming their role in controlling branch and petiole angles. …”
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    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

    Published 2022
    “…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. Primary alkylamine derivatives coupled through a <i>p</i>-amido group with a varying methylene chain length (<b>24</b> and <b>25</b>) were functionalized congeners, for subsequent conjugation to carrier or reporter moieties. …”
  14. 7234

    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

    Published 2022
    “…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. Primary alkylamine derivatives coupled through a <i>p</i>-amido group with a varying methylene chain length (<b>24</b> and <b>25</b>) were functionalized congeners, for subsequent conjugation to carrier or reporter moieties. …”
  15. 7235

    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

    Published 2022
    “…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. Primary alkylamine derivatives coupled through a <i>p</i>-amido group with a varying methylene chain length (<b>24</b> and <b>25</b>) were functionalized congeners, for subsequent conjugation to carrier or reporter moieties. …”
  16. 7236

    Data Sheet 2_Screening of neurotransmitter receptor modulators reveals novel inhibitors of influenza virus replication.pdf by Yarou Gao (20620991)

    Published 2025
    “…We identified 20 candidate compounds with IC50 values below 20 μM, suggesting a critical role for these receptors in influenza replication. …”
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