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12641
Data Sheet 1_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf
Published 2025“…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …”
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12642
Data Sheet 3_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf
Published 2025“…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …”
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12643
Data Sheet 2_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf
Published 2025“…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …”
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12644
Image_1_Long-Term Increase in Cholesterol Is Associated With Better Cognitive Function: Evidence From a Longitudinal Study.TIF
Published 2021“…</p><p>Methods: A total of 4,915 participants aged ≥45 years with normal cognition in baseline were included. …”
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12645
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12646
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12647
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12648
Table 1_Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study.docx
Published 2025“…Bioimpedance analysis was conducted using a phase-sensitive foot-to-hand technology at 50 kHz. …”
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12649
Table 2_Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study.docx
Published 2025“…Bioimpedance analysis was conducted using a phase-sensitive foot-to-hand technology at 50 kHz. …”
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12650
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12651
<i>Pax2.1</i> and <i>pax6a</i> expression is altered in <i>sox11</i> morphants.
Published 2014“…Relative transcript abundance was normalized to <i>atp5h</i> (18 hpf) or <i>gapdh</i> (24 hpf) levels and is presented as the mean fold-change in expression relative to controls (n = 50 embryos per group, 3 independent biological replicates. …”
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12652
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12653
A Divergent Artiodactyl <i>MYADM</i>-like Repeat Is Associated with Erythrocyte Traits and Weight of Lamb Weaned in Domestic Sheep
Published 2013“…A single nucleotide polymorphism (SNP) showed genome-wide significant association with increased mean corpuscular hemoglobin concentration (MCHC, <i>P</i> = 6.2×10<sup>−14</sup>) and genome-wide suggestive association with decreased mean corpuscular volume (MCV, <i>P</i> = 2.5×10<sup>−6</sup>). …”
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12654
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12655
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12658
Metformin requires transcription factor SKN-1 to increase median lifespan, via a mechanism that acts in both ASI neurons and the intestine.
Published 2010“…Pooled data for <i>skn-1(zu135)</i> mutants expressing <i>skn-1::gfp</i> only in the ASI neurons show a median lifespan decrease from 16 days for animals on 0 mM metformin to 13 days for animals on 50 mM metformin, with a significantly left-shifted survival curve (<i>P</i><0.0001 by the Log-rank test, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008758#pone.0008758.s005" target="_blank">Table S1G</a>). …”
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12659
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12660
Data_Sheet_1_Pharmacokinetics Alterations in Critically Ill Pediatric Patients on Extracorporeal Membrane Oxygenation: A Systematic Review.docx
Published 2020“…Increase in volume of distribution attributable to ECMO was demonstrated for nine (56%) drugs: cefotaxime, gentamicin, piperacillin/tazobactam, fluconazole, micafungin, levetiracetam, clonidine, midazolam, and sildenafil (range: 23–345% increase relative to non-ECMO controls), which may suggest the need for higher initial dosing. Decreased volume of distribution was reported for two drugs: acyclovir and ribavirin (50 and 69%, respectively). …”