Supplementary Material for: Design and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial by Bakris G.L. (4681903)

“…The study has at least 90% power to detect a 20% reduction in the risk of primary outcome (overall two-sided significance level α = 0.05), the composite of time to first occurrence of kidney failure, a sustained decrease of eGFR ≥40% from baseline over at least 4 weeks, or renal death. …”

QUALIS: The journal ranking system undermining the impact of Brazilian science by RODOLFO JAFFÉ (10364631)

In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts by K. K. Dar (6274934)

“…The intraperitoneal administration of B. ciliata as a protective agent, produced significant increase in albumin levels with significant decrease in the levels of tumor markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. …”

In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts by K. K. Dar (6274934)

“…The intraperitoneal administration of B. ciliata as a protective agent, produced significant increase in albumin levels with significant decrease in the levels of tumor markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. …”

Manifold transformation in the familiarity association experiment. by Weifan Wang (4669081)

“…<b>(E)</b> Across noise levels, and over the first 200 epochs show a two-phase trajectory: a minimum at epoch 30 (dashed line), and an overall decrease. …”

DKT promoted the repair of the mucosal barrier and nutrient absorption functions. by Peilin Li (586356)

“…<p><b>(A)</b> The plasma DAO level in the control, MTX, DKT-MTX, and DKT groups. …”

Evaluation of cytotoxicity and wound healing activity of Avicennia schaueriana in cream by CAROLINE M.I. LOPES (6571217)

“…A. schaueriana did not show cytotoxicity. Furthermore, topical application of AELAs cream decreased the wound area, stimulated the re-epithelialization and increased the number of fibroblasts. …”

Average bacterial counts from mouse blood TIGR4 and Δ<i>idtr</i>. by Radha Gupta (378230)

“…<p>A group of 5 mice each were infected intravenously with 10⁵ CFU of TIGR4 or Δ<i>idtr</i>. …”

Table_1_Estimation of Cerebral Hemodynamics and Oxygenation During Various Intensities of Rowing Exercise: An NIRS Study.docx by Mikio Hiura (12176669)

“…We also aimed to examine the effects of peak pulmonary oxygen consumption (V.O_2peak) on cerebral oxygenation.</p>Methods<p>Eleven rowers, consisting out of six athletes and five recreational rowers [two female; age, 27 ± 9 years; height, 171 ± 7 cm, body mass, 67 ± 9 kg; V.O_2peak, 53.5 ± 6.5 mL min^–1 kg^–1] rowed a 13-min session separated by 10 and 3 min, at 70 (Ex_70%) and 80% of V.O_2peak (Ex_80%), respectively, on a rowing ergometer, followed by three sessions of 1-min supramaximal exercise (ExSp). …”

Characterization of α-syn pores. by Felix Schmidt (312801)

“…<p><b>A</b>) Depending on clamped voltage, the number of steps increasing or decreasing pore conductance (“G-up” and “G-down” refer to the number of steps per recorded trace of 10s) differs (N = 18804 steps in 74 pore formations with 42 traces each). …”

Optimization of TEV protease cleavage conditions. by Yu-Fu Hung (513472)

“…The different “+” font sizes indicate the increasing amounts of TEV protease with fusion peptide to protease molar ratios of approximately 100, 50 and 10. The progress of the TEV digest is monitored by observing the decrease of the band of the dual tagged GST-GB1-NS4A(1–48) fusion protein and a parallel increase of the free GST-GB1 dual tag band (B, D).…”

TIME SERIES TRENDS OF STREAMFLOW AND RAINFALL IN THE SANTO ANTÔNIO RIVER BASIN, BRAZIL by Fernanda L. V. Ferreira (10383961)

Pairwise variant allele frequency (VAF) histograms for virtual primary tumors. by Ruping Sun (10319284)

“…Variants were classified as public (gray), shared (green, subclonal variants shared in the two regions in comparison), or region specific (blue) on the basis of their presence in the virtual multi-region sequencing (5 regions in total) [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008838#pcbi.1008838.ref018" target="_blank">18</a>]. …”

Grain Yield Losses and Economic Threshold Level Of GR® F2 Volunteer Corn in Cultivated F1 Hybrid Corn by C. PIASECKI (5054501)

“…Increases in corn grain yield and price paid, higher corn control efficiency, and a decrease in control costs promote a reduction in ET of volunteer corn in corn.…”

Impact of Ketamine on HK2 cell viability, as assessed by phase contrast microscopy, MTT uptake, Crystal Violet staining and LDH release. by Claire E. Hills (452020)

“…Incubation with Ketamine at 0.5 and 1 mg/mL caused a significant decrease in viable cells as measured by MTT uptake. …”

Table_1_Glucocorticoid Effects on Tissue Residing Immune Cells in Giant Cell Arteritis: Importance of GM-CSF.XLSX by Annette D. Wagner (6496358)

“…A decrease of CCL19 and CCL21 expression was observed after starting glucocorticoid therapy. …”

Image_2_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

Image_4_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

Table_2_Glucocorticoid Effects on Tissue Residing Immune Cells in Giant Cell Arteritis: Importance of GM-CSF.DOCX by Annette D. Wagner (6496358)

“…A decrease of CCL19 and CCL21 expression was observed after starting glucocorticoid therapy. …”

Luminex results of cytokines regulated by IL-1Ra. by Connie S. Chamberlain (440242)

“…Blockade of the IL-1 activation resulted in an accumulation of IL-1α (a) and IL-1β (b). By day 11, inhibition of the IL-1R resulted in a down-regulation of IL-1α (a) and tended to decrease IL-1β (b; p = .056). …”