DataSheet_1_Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models.pdf by Emilia J. Berthold (13839388)

“…</p>Results<p>Both CsA and ALV robustly inhibited viral replication in all models; both compounds decreased HCoV-229E RNA in phBECs and reduced luminescence in HCoV-229E-RLuc-infected Huh7.5 and SARS-CoV-1-RLuc replicon-transfected HEK293. …”

O-GlcNAc immunoprecipitation (IP) for carnitine palmitoyltransferase 1B (CPT1B). by Wei Zhong Zhu (14014073)

Additional file 6 of ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy by Lihong Lu (10532648)

“…(D) Compared with the control group, the mRNAexpression of KMT5A was decreased in aortic tissues of DN rats. (* p < 0.05,** p < 0.01, *** p < 0.001, **** p < 0.0001, n = 10/group).…”

m⁶A mRNA methylation controls autophagy and adipogenesis by targeting <i>Atg5</i> and <i>Atg7</i> by Xinxia Wang (301455)

“…Mechanistically, knockdown of FTO, a well-known m⁶A demethylase, decreased the expression of ATG5 and ATG7, leading to attenuation of autophagosome formation, thereby inhibiting autophagy and adipogenesis. …”

The <i>sf3b1-698</i> mutants are defective in fecundity and lifespan. by Bei Zhang (428038)

“…Females of the two sf3b1 mutants laid no significantly changed eggs during the late half of test time. Means: WT = 175, H698D = 195.5, p = 0.5296, H698R = 173.4, p = 0.9437. …”

Additional file 3 of ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy by Lihong Lu (10532648)

Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer by Hong Im Kim (4686187)

“…Spermidine is required for the hypusine-dependent activation of eukaryotic translation initiation factors 5A1 (eIF5A1) and 5A2 (eIF5A2) and connects the MYC/ODC-induced deregulation of spermidine to eIF5A1/2 protein translation, which is increased during cancer cell proliferation. …”

Data_Sheet_1_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.DOCX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Data_Sheet_2_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLS by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

Data_Sheet_3_SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2.XLSX by Ai Qing Yu (9774356)

“…Decrotonylation of PHF5A K25 contributed to decreased CDK2 expression by retained intron (RI)-induced abnormal AS, thereby accelerating fibroblast senescence, and supporting a key role of PHF5A K25 decrotonylation in aging. …”

A new resource allocation model partitions the genome in five expression sectors. by Mónica Chagoyen (4253800)

“…<p><b>A)</b> Top. Resource allocation model (Model 1) based on three sectors in which the expression of their constituent genes increases (positive genes, blue), decreases (negative genes, red), or remains constant (invariant genes, brown) with increasing growth rate. …”

<i>Pbpp6</i> gene deletion/disruption and analysis. by Yonghui Feng (12227596)

Quantifying the Contribution of Statins to the Decline in Population Mean Cholesterol by Socioeconomic Group in England 1991 - 2012: A Modelling Study by Chris Kypridemos (719751)

“…In our ‘no statins’ scenario we predicted a mean total cholesterol of 5.36 mmol/L (95% CI: 5.33-5.40) for 2011-12. …”

Kcnk5b activity induces IP₃R-mediated Ca²⁺ release from the ER. by Xiaowen Jiang (8291814)

Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children by Charles Arama (159942)

“…</p><p>Results</p><p>The minor allele frequency of the A443T, I474V, E670G, and C679X polymorphisms in the study population sample was 0.12, 0.20, 0.26, and 0.02, respectively. …”

Plot of the density profiles in the (a) stable and (b) expansion regions for the potential (5) by J B Sudharsan (557453)

“…</strong> Plot of the density profiles in the (a) stable and (b) expansion regions for the potential (<a href="http://iopscience.iop.org/0953-4075/46/15/155302/article#jpb466473eqn05" target="_blank">5</a>).…”

Pim1 inhibition results in a reduced visual response at 5 dpf. by Jun Yin (94374)

“…Pim1 inhibitors were dissolved in 0.1% DMSO at all concentrations except the 100 µM concentration which was dissolved in 1% DMSO. (B) The ERG a-wave and b-wave are significantly decreased in 100 µM Pim1 inhibitor 2 treated fish. …”

The R code that was used to graph the acid dissociation data for H₃As(V)O₄ in S4 File. by Seth H. Frisbie (7821866)

PM2.5 associates with blood pressure: a Mendelian randomization analysis by Minghui Bao (767132)

“…<p>The relationship between fine particulate matter (PM2.5) and blood pressure (BP) is a controversial issue. …”

Image5_Cancers and erectile dysfunction: a Mendelian randomization study.tiff by Ge Yang (169466)