Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. These investigations reveal that a number of 2,9-diazaperopyrenium dications show similar activities as doxorubicin toward a variety of cancer cell lines. …”

Synthesis and Activity of a Novel Autotaxin Inhibitor–Icodextrin Conjugate by Natalie Fisher (1860283)

“…The conjugate inhibits autotaxin activity (IC₅₀ = 0.86 ± 0.13 μg mL^–1) and reduces cell migration. …”

Rectal PICLC modestly decreases SIV transmission but increases SIVΔNef replication in infected animals and promotes the vaccine effect. by Meropi Aravantinou (51206)

Inhibition of <i>T</i>. <i>cruzi</i> G strain MT internalization and host cell lysosome spreading by purified G-MUC. by Thiago Souza Onofre (6880925)

Interference with the <i>kgb-1</i> MAPK pathway decreases oxidative stress sensitivity in <i>ttr-33</i> mutants. by Sarah-Lena Offenburger (669498)

Silencing class II PI3Ks decreases autophagy in both control and <i>Vps34</i> null MEFs. by Kelly Devereaux (466106)

eNOS^-/- decreased the number of oligodendrocytes and OPCs but not demyelination in the ischemic striatal bundles 7 days after stroke. by Xu Cui (261214)

Multi-way sensitivity analysis on transmission rate, CD4 count at diagnosis, and ART costs in a model-based analysis of Immediate ART initiation in Côte d’Ivoire. by Eric N. Ouattara (6890174)

Effect of V3, MPER and IDR peptides on ID50 neutralization titers of the cross-neutralizing plasma in depletion and competition experiments. by Raiees Andrabi (138046)

“…</p>b<p><b>ID₅₀ fold decrease</b>; Plasma ID50 fold decrease for depletion assay was calculated as, ID50 with mock depleted plasma/ID50 with V3, MPER and IDR depleted plasma, and for competition assay as ID50 with untreated plasma/ID50 with V3, MPER and IDR treated plasma. …”

Schematic illustrations of different scaffold internal structures; A) lattice, B) staggered. by Zahra Yazdanpanah (10038944)

Treatment of cancer cells with FL118 significantly decreases BrdU positive cells (proliferative cells) and induces apoptotic markers. by Xiang Ling (307318)

Populations activity of the <i>eirs</i>-NFT model. by Felipe A. Torres (11210983)

MiR-145 protected against H2O2-induced mitochondrial structural disruption and decreased the ROS production. by Ruotian Li (307097)

Adaptation of SARS-CoV-2_Engl2 to VeroE6 and selection of decreased RDV sensitivity. by Agnieszka M. Szemiel (10196243)

Loss of <i>jag1b</i> function decreases the penetrance of <i>mef2ca</i>-associated phenotypes. by Juliana Sucharov (8067371)

“…Removing functional copies of <i>jag1b</i> decreased <i>mef2ca</i> mutant penetrance. Scale bar: 50 μm. …”

Decreased Connexin 40 expression in CHAPb Tg left atrium at 6 months of age leads to atrio-ventricular conduction delay. by Willemijn van Eldik (4662955)

MAVS deficient mice display decreased polyclonal CD8⁺ T cell responses and increased viral loads in the lungs. by Matheswaran Kandasamy (105167)

Decreased cardiomyocyte proliferation in <i>Nkx2.5-Cre/Foxm1^fl/fl</i> hearts. by Craig Bolte (299486)

“…“N” values were represented by boxes inside bars. Scale bars represent 50 µm in A–H and J–K and 10 µm in insets E–H.</p>…”

ISA27 induces the stabilisation of p53 protein levels by decreasing the interaction of p53 with MDM2 in GBM cells. by Barbara Costa (447711)

Comparison of diffusion simulations: implicit scheme of the GDE with a 30-second time step (blue line), implicit scheme of the PNGM with α = 0.6 and a 15-second time step (green li... by Mouad Klai (20818364)