Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Prognostic value of PLA2R autoimmunity detected by measurement of anti-PLA2R antibodies combined with detection of PLA2R antigen in membranous nephropathy: A single-centre study ov... by Franck Pourcine (3812968)

“…We also assessed THSD7A status.</p><p>Results</p><p>Eighty-five patients suffered from primary MN (PMN) and 23 patients from a secondary form. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Hesperidin alleviates pulmonary fibrosis by regulating EI24-mediated autophagy by Yan Zhang (8098)

Including cell content predictions in the analysis of microarray data improves model fit and enhances the detection of previously-identified diagnosis-related genes in some dataset... by Megan Hastings Hagenauer (5523191)

“…M5, M3 vs. M5). Bottom graphs: In some datasets we see an enrichment of psychiatric effects (*p<0.05) in previously-identified psychiatric gene sets only after controlling for cell type (Barnes: M3, M4, Pritzker: M5, M3). …”

Data_Sheet_1_Antimicrobial Usages and Antimicrobial Resistance in Commensal Escherichia coli From Veal Calves in France: Evolution During the Fattening Process.PDF by Emilie Gay (142664)

“…Our study also highlighted that if only ESBL-producing isolates were monitored, it might have led to a partial (and partly false) picture of AMR rates globally decreasing during the fattening period. …”

The stress-related, rhizobial small RNA RcsR1 destabilizes the autoinducer synthase encoding mRNA <i>sinI</i> in <i>Sinorhizobium meliloti</i> by Kathrin Baumgardt (828726)

“…During the analysis of the post-transcriptional regulation of quorum sensing in the nitrogen fixing plant symbiont <i>Sinorhizobium meliloti,</i> we predicted and verified a direct interaction between the 5'-UTR of <i>sinI</i> mRNA encoding the autoinducer synthase and a small RNA (sRNA), which we named RcsR1. …”

Data_Sheet_1_Nonlinear dynamics of postural control system under visual-vestibular habituation balance practice: evidence from EEG, EMG and center of pressure signals.docx by Anke Hua (18449610)

“…We asked participants to undergo repeated exposure to either congruent (n = 14) or incongruent condition (n = 13) five times while maintaining balance. …”

Supplementary Material for: Identifying novel inflammatory protein biomarkers and drug targets of inflammatory bowel disease by integrating Mendelian randomization, bioinformatics,... by Wang F. (3215361)

“…Results: By integrating data from two cohorts, we demonstrated that genetically predicted CD40 (odds ratio [OR] = 0.878, 95% confidence interval [CI] = 0.838-0.919) and C-X-C motif chemokine ligand (CXCL)5 (OR = 0.884, 95%CI = 0.841-0.930) decreased IBD risk. …”

Image_3_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_1_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_1_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_4_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIFF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Image_2_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.TIF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”

Data_Sheet_2_Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders.PDF by Julia I. Ellyard (7369643)

“…We observed differences between unaffected and affected TACI mutants (increased B cells and CD8+ T-effector memory cells, loss of B-SM cells and non-classical monocytes), cellular signatures that distinguished CTLA4 haploinsufficiency itself (expansion of plasmablasts, activated CD4+ T cells, regulatory T cells, and X5-Th cells) from its clinical expression (B-cell depletion), and those that were associated with CARD11 gain-of-function mutation (decreased CD8+ T effector memory cells, B cells, CD21-lo B cells, B-SM cells, and NK cells). …”