ISL inhibited tumor growth and angiogenesis on MDA-MB-231 breast cancer xenografts. by Zhiyu Wang (282312)

“…<p>(A) Nude mice bearing breast cancer were treated with the vehicle or ISL (25 and 50 mg/kg/d). …”

A3 adenosine receptors modulate behavior and serotonergic system in zebrafish: Mediation by the nitric oxide pathway by Caio Maximino (100467)

“…Here, we demonstrate that activation of A3 adenosine receptors by IB-MECA decreases scototaxis, geotaxis, neophobia and arousal in zebrafish in vivo, increases extracellular brain 5-HT levels ex vivo, and increases 5-HT uptake in vitro. …”

Global and local distances for several configurations of the system. by Iván Y. Fernández-Rosales (732896)

“…(a) For global distance, we observe the smallest value when <i>p</i> = 0 and <i>r</i> ≈ 0.5, then the distance increases as <i>r</i> increases or decreases. …”

DataSheet_1_Non-viral-mediated gene transfer of OX40 ligand for tumor immunotherapy.pdf by Olga A. Rakitina (18883519)

Axonal outgrowth in the injured spinal cord after high-dose ChABC treatment. by Chu-Hsun Cheng (798713)

“…<p>Longitudinal spinal cord sections from the control (A, D) and the 50 U (B, E) and 100 U (C, F) ChABC-treated groups were labeled with β-III tubulin (red) and GFAP (green, astrocytes) at 4 (A-C) and 10 (D-F) weeks after spinal cord injury; the dotted square indicates the higher magnification image of the lesion epicenter in each group (A’-F’). …”

Quality of sorghum silage with leucaena by Weudes Rodrigues Andrade (6186503)

“…There was an increasing linear effect (p < 0.05) for the content of dry matter (DM), crude protein (CP) and lignin that increased from 33.47 to 34.75%, 7.82 to 16.05% and from 7.29 to 9.93%, at the levels from 0 to 50% inclusion of leucaena, respectively. There was a decreasing linear effect (p < 0.05) for neutral detergent fiber corrected for ash and protein (NDFcp) and hemicellulose, which reduced from 56.65 to 48.37% and from 24.07 to 17.67% at the levels of 0 and 50% inclusion, respectively. …”

Influence of NOD on TNF-α mediated NFκB activation. by Maximilia C. Hottenrott (452847)

“…During stimulation NOD (50 µM) was absent (−) or present (+). Nuclear extracts were prepared and assessed for NFκB activation by means of EMSA. …”

Microcystins as new therapeutic agents for OATP1B3 expressing tumors _ Poster at ICNPR2012.pdf by Timo Niedermeyer (98677)

“…Thus selectivity that favors OATP1B3 over OATP1B1 should lead to a decreased hepatic clearance and toxicity, and an increased uptake in OATP1B3-expressing tumors, thus creating a therapeutic window for the respective compound.…”

Proliferation and demyelination in the early stages after crush injury. by Anna Henzi (9635793)

“…Scale bar: 50 μM. (b) Ki67-proliferation index (% ki67-positive nuclei) as quantified from IF images was highest at 5 d.p.c. and decreased at later stages post crush injury. …”

Effect of CSE Gene Deletion on Liver and Lung MPO Activity and Organ Injury in Mice Following CLP Induced Sepsis. by Ravinder Reddy Gaddam (2939934)

“…This effect was substantially reduced in the CLP induced CSE KO mice. Scale bar is 50 μm. Data represent the mean±standard deviation (n = 8). …”

MEK kinase positively and transcriptionally controls CD70 membrane and global expression. by Christine Pich (367328)

“…<p>LB1319-MEL and WM-266-4 cells were treated with 5 μM of U0126 for 72 h then analyzed by Western Blot for CD70, phospho-MEK and MEK expression. Actin was used as a loading control <b>(A)</b>. LB39-MEL CD70+ cells were treated with 5 μM of U0126 for 72 h then fixed and processed for immunofluorescence directed against CD70. …”

Aa EV-induced proinflammatory cytokine expression is blocked in <i>MyD88</i>^<i>-/-</i> mice. by Jae Yeong Ha (9676175)

“…<p>DiD-labeled Aa EVs (approximately 2.25 × 10⁹ particles in 50 μl of PBS) were gingivally injected in WT and <i>MyD88</i>^<i>-/-</i> mice after ligature-induced necrosis (n = 6 per each group). …”

Data_Sheet_1_Socioeconomic and Environmental Factors Associated With Increased Alcohol Purchase and Consumption in 38 Countries During the Covid-19 Pandemic.docx by Zaheer Kyaw Hla (11946203)

“…</p>Setting<p>Thirty-eight countries from all continents of the world.</p>Participants<p>A total of 37,206 adults (mean age:36.7, SD:14.8, 77% female) reporting alcohol purchasing and drinking habit before and during the pandemic.…”

Method Scaling. by Upinder S. Bhalla (49063)

“…More axons improved input coverage, but the number of possible trials decreased. There was a peak of ∼50 detected synapses per neuron, for ∼6000 axons.…”

Obtaining and characterizing “dulce de leche” prepared with sheep’s and cow’s milk in different proportions by Pâmela Cristina LIMA (10462453)

“…From inclusion of sheep’s milk, the DL presented higher values of total solids, ashes and protein, with lipids increased only from the proportion 50:50. Lactose decreased at the proportion 0:100, however, was similar to the 25:75 proportion. …”

Transient ERK1/2 dephosphorylation induces dissociation of Jarid2 and Ring1B and chromatin decompaction in NMP-L cells at the <i>PAX6</i> locus but does not reduce H3K27me3 nor eli... by Claudia I. Semprich (14204821)

“…Interprobe distance measurements in >50 nuclei in the three conditions in three individual experiments (<i>n</i> = > 150 nuclei/cell type, Mann–Whitney test/rank-sum test, *** <i>p</i> ≤ 0.001) (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000221#pbio.3000221.s024" target="_blank">S10 Data</a>), this decompaction correlated with a 2.5-fold decrease in number of base pairs per nm compared to both controls (untreated NMP-L (D3): 205 bp/nm, DMSO NMP-L (D3): 218 bp/nm and MEKi NMPL (D3): 87 bp/nm). …”

Trio overexpression in class IV da neurons. by Srividya Chandramouli Iyer (177446)

“…As compared to control (<b>A</b>), Trio overexpression results in decreased dendritic branching (<b>B</b>). …”

Examining the Lateral Displacement of HL60 Cells Rolling on Asymmetric P-Selectin Patterns by Chia-Hua Lee (2239972)

“…On the basis of these experimental data, we constructed an empirical model that predicted the occurrence of the maximum lateral displacement at an edge angle of 7.5°. …”

Image_1_Sex differences in motor learning flexibility are accompanied by sex differences in mushroom spine pruning of the mouse primary motor cortex during adolescence.JPEG by Michael Tekin (18989888)

“…Cognitive flexibility is associated with low baseline mushroom spine densities achieved by pruning which can be triggered by α4βδ GABAA receptors (GABARs); defective synaptic pruning impairs this process.</p>Methods<p>We investigated sex differences in adolescent pruning of mushroom spine pruning of layer 5 pyramidal cells of primary motor cortex (L5M1), a site essential for motor learning, using microscopic evaluation of Golgi stained sections. …”

<b><i>Original data for "High risk of soil available silicon deficiency in bamboo forest: Insights from bamboo afforestation chronosequences in the karst region of southwest China"... by Kangning Yan (22751487)

“…By comparing the variation of five soil ASi proxies, we found that 0.01 M CaCl2 extractable Si (CaCl2-Si, 5.05–26.72 mg kg–1) and water extractable Si (H2O-Si, 4.20–19.89mg kg–1) were the only two proxies that exhibited a consistent declining trend with increasing stand age across all soil layers. …”