image_1_Acute Zika Virus Infection in an Endemic Area Shows Modest Proinflammatory Systemic Immunoactivation and Cytokine-Symptom Associations.jpeg by Jéssica Barletto de Sousa Barros (5167421)

“…Of note, we found that higher levels of IP-10 and IL-5 in ZIKV-infected individuals were strongly associated with exanthema and headache, respectively. …”

DataSheet1_A Major Downregulation of Circulating microRNAs in Zika Acutely Infected Patients: Potential Implications in Innate and Adaptive Immune Response Signaling Pathways.pdf by Ana Carolina Carvalho-Silva (12706811)

“…We observed that during ZIKV acute infection, among the dysregulated miRNAs (DMs), the majority is with decreased levels when compared to convalescent and control patients. …”

Table_1_Csf2 Attenuated Sepsis-Induced Acute Kidney Injury by Promoting Alternative Macrophage Transition.XLSX by Yiming Li (40290)

“…In addition, the switch from the proinflammatory M1 phenotype to the M2 phenotype occurred via the p-Stat5 pathway, which was activated by Csf2. Importantly, we found that intraperitoneal injection of a Csf2-neutralizing antibody after CLP aggravated kidney injury and suppressed tubular proliferation, subsequently decreasing survival. …”

Table1_Effects of metformin on acute respiratory distress syndrome in preclinical studies: a systematic review and meta-analysis.doc by Liu Wang (213066)

“…Pooled results showed metformin effectively decreased pulmonary wet-to-dry weight ratios [SMD = −2.67 (−3.53 to −1.81), I² = 56.6%], protein content [SMD = −3.74 (−6.76 to −0.72), I² = 86.7%] and neutrophils [SMD = −3.47 (−4.69 to −2.26), I² = 0%] in BALF, pulmonary malondialdehyde [SMD = −1.98 (−3.77 to −0.20), I² = 74.2%] and myeloperoxidase activity [SMD = −3.15 (−4.79 to −1.52), I² = 74.5%], lung injury scores [SMD = −4.19 (−5.65 to −2.74), I² = 69.1%], and mortality at 24 h [RR = 0.43 (0.24–0.76), I² = 0%] as well as 48 and 72 h.…”

Squirrel Abundance by Angela Joseph (631109)

“…The size of the squirrels were visually observed based on how big they were and were scaled from 1-5, where 1 was a small squirrel and 5 was a large squirrel.…”

<b>Wheat density, not weed density, drives negative density dependence in nitrogen uptake and root plasticity in wheat–weed communities</b> by weiqiang liu (19824330)

“…Beauv.) with varying densities (4, 8, 12, 16 individuals per pot) and proportions (wheat:weed 0:1, 0.25:0.75, 0.5:0.5, 0.75:0.25, 1:0), with and without fertilization. …”

Household Knowledge of Antimicrobials and Antimicrobial Resistance in the Wake of an Accredited Drug Dispensing Outlet (ADDO) Program Rollout in Tanzania by Daudi Simba (3184989)

“…Within the regions, we applied a multistage cluster sampling design, cascading from districts, wards, and villages to households. …”

Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy by Amanda H. Kahn-Kirby (5634986)

“…</p><p>Results</p><p>EPI-743 potently prevented ferroptosis in patient cells representing five distinct pediatric disease syndromes with associated epilepsy. …”

UPPAAL SMC model specification by Marc Souvannasouck (16475829)

“…Upon the completion of this month, the model transitions to a branchpoint and adds a monthly cost of 50 to the total cost, denoting a constant monthly expense for treatment management. …”

Inhibition of tumorgeneic activity in Oct-4 siRNA-treated LC-CD133⁺ with chemoradiotherapy. by Yu-Chih Chen (151468)

“…<p>LC-CD133⁺-GFP (10⁴) cells of different treatment groups were injected into the subcutaneous sites of nude mice. (A) The tumor volume and (B) The number of pulmonary tumor nodules were significantly decreased in Oct-4 siRNA-treated LC-CD133⁺ when exposed to IR alone, cisplatin alone, or IR combined with cisplatin. …”

The average angle of spindle orientation is randomized in all mutants. by Tiziano Pramparo (176331)

“…On the right, the average angle of spindle orientation is affected by decreasing dosage of <i>Dcx</i> (100%>0%) and <i>Lis1</i> (100%>50%>35%) proteins as already published <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1001331#pgen.1001331-Pramparo1" target="_blank">[14]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1001331#pgen.1001331-Yingling1" target="_blank">[17]</a>. …”

Sirt1 regulates central melanocortin system. by Işin Çakir (256194)

“…(<i>D</i>) Resveratrol decreases POMC expression in AtT20 cells in a Sirt1- and dose-dependent manner. …”

Estimated median (and inter-quartile range) probability (%) of developing life-long immunity after HPV infection clearance by HPV type. by Iacopo Baussano (234638)

“…<div><p>As the probability decreases from 50% to 0%, HPV infections are increasingly more likely to be cleared without developing immunity, i.e. increasingly characterized by a predominant SIS clearance pattern. …”

Image_1_18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways.TIF by Xiao Chen (2756308)

“…For underlying molecular mechanisms, 18β-GA inhibited RANKL-induced phosphorylation of p65, p50, and IκB, blocked p65 nuclear translocation and decreased the DNA-binding activity of NF-κB. …”

DataSheet1_Freeze-thaw cycles alter soil hydro-physical properties and dissolved organic carbon release from peat.docx by Haojie Liu (7397144)

“…The soil samples were subject to five freeze-thaw treatments, including a zero, one, three, five, ten cycles (FTC0, FTC1, FTC3, FTC5, and FTC10, respectively). …”

Video_1_Case report: Filarial infection of a parti-coloured bat: Litomosa sp. adult worms in abdominal cavity and microfilariae in bat semen.MP4 by Jiri Pikula (562609)

“…</p>Methods<p>For the first time we performed electroejaculation and used computer-assisted semen analysis to provide baseline data on semen quality in a parti-coloured bat (Vespertilio murinus).…”

Data_Sheet_1_One vaccine to counter many diseases? Modeling the economics of oral polio vaccine against child mortality and COVID-19.docx by Angela Y. Chang (1759720)

“…This paper addresses that gap by reporting economic evaluations of the NSE of oral polio vaccine (OPV) against under-five mortality and COVID-19.</p>Materials and methods<p>We studied two settings: (1) reducing child mortality in a high-mortality setting (Guinea-Bissau) and (2) preventing COVID-19 in India. …”

sCLU protects cells from senescence. by Xiuquan Luo (579204)

“…In these experiments, IMR-90 cells were cultured in 95% air-5% CO₂, estimated at ∼20% O₂.…”

Structural Distortions upon Oxidation in Heteroleptic [Cp₂W(dmit)] Tungsten Dithiolene Complex: Combined Structural, Spectroscopic, and Magnetic Studies by Eric W. Reinheimer (547881)

“…Four different cation radical salts are obtained upon electrocrystallization of [Cp₂W(dmit)] (dmit = 1,3-dithiole-2-thione-4,5-dithiolato) in the presence of the BF₄⁻, PF₆⁻, Br⁻, and [Au(CN)₂]⁻ anions. …”

Nonheme Oxoiron(IV) Complexes of Tris(2-pyridylmethyl)amine with <i>cis</i>-Monoanionic Ligands by Jan-Uwe Rohde (1985752)

“…Some characteristic features of the <i>S</i> = 1 oxoiron(IV) unit are quite insensitive to the ligand substitution in the equatorial plane, namely, the Fe−O distances (1.65−1.66 Å), the energy (∼7114.5 eV) and intensity [25(2) units] of the 1s-to-3d transition in the X-ray absorption spectra, and the Mössbauer isomer shifts (0.01−0.06 mm·s^-1) and quadrupole splittings (0.92−0.95 mm·s^-1). …”