Showing 1,141 - 1,160 results of 63,109 for search '(( 50 ((mean decrease) OR (a decrease)) ) OR ( 5 ((nm decrease) OR (we decrease)) ))', query time: 1.49s Refine Results
  1. 1141
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    Microparticles Engineered to Highly Express Peroxisome Proliferator-Activated Receptor-γ Decreased Inflammatory Mediator Production and Increased Adhesion of Recipient Monocytes by Julie Sahler (666499)

    Published 2014
    “…Herein, we tested the responses of monocytes exposed to either control microparticles or microparticles that contain the anti-inflammatory transcription factor, peroxisome proliferator-activated receptor-γ (PPARγ). …”
  3. 1143
  4. 1144

    Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease by Huashen Xu (13987046)

    Published 2025
    “…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC<sub>50</sub> = 0.1 nM, msEH IC<sub>50</sub> = 0.1 nM). …”
  5. 1145

    Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease by Huashen Xu (13987046)

    Published 2025
    “…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC<sub>50</sub> = 0.1 nM, msEH IC<sub>50</sub> = 0.1 nM). …”
  6. 1146

    Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease by Huashen Xu (13987046)

    Published 2025
    “…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC<sub>50</sub> = 0.1 nM, msEH IC<sub>50</sub> = 0.1 nM). …”
  7. 1147

    Design and Synthesis of Novel sEH Inhibitors for the Treatment of Inflammatory Bowel Disease by Huashen Xu (13987046)

    Published 2025
    “…Especially, lead compounds <b>A1</b> and <b>A9</b> showed potent inhibitory activities against sEH (<b>A1</b> and <b>A9</b>; hsEH IC<sub>50</sub> = 0.1 nM, msEH IC<sub>50</sub> = 0.1 nM). …”
  8. 1148

    rAd-p53 induces apoptosis in HCC cell lines with increased Fbxw7 and decreased c-Myc and Cyclin E. by Kangsheng Tu (428934)

    Published 2013
    “…<p>A) MTT activity was measured after infecting Hep3B cells with rAd-p53 in an MOI gradient to determine their IC<sub>50</sub> after 48 h. …”
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  13. 1153
  14. 1154
  15. 1155

    Overexpression of let-7b decreases NF-κB activity and downregulates COX-2, CyclinD1 protein expression. by Gui-gen Teng (380044)

    Published 2013
    “…(C–D) Overexpression of let-7b by mimics downregulated MyD88, p65/RelA, P50/NF-κB1 and IL-8 mRNA levels, and decreased NF-κB luciferase activity compared to let-7b negative control. …”
  16. 1156
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  18. 1158

    Injection of rIL-6 in IL-6KO mice decreased chronic disease severity following CB3/LPS treatment. by Maya C. Poffenberger (262165)

    Published 2009
    “…(B) Chronic cardiac disease histology was scored blindly by a four tier grading system to determine severity differences: grade 1, 0–10% pathology; grade 2, 11–25%; grade 3, 26–50%; grade 4, greater than 50% (black circles indicate wt mice with DMEM, white circles indicate IL-6KO mice with DMEM, grey circles indicate IL-6KO mice with rIL-6) (bar is mean±SE, *p<0.05). …”
  19. 1159
  20. 1160

    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

    Published 2021
    “…Here, by addressing a high-energy water, we improved the IC<sub>50</sub> value of our co-crystallized glycogen synthase kinase-3β (GSK-3β) inhibitor by nearly two orders of magnitude. …”