Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling by Mariliis Tark-Dame (641719)

“…The molecular basis for this counter-intuitive behaviour is explored by polymer modelling usingy the Dynamic Loop model (Bohn M, Heermann DW (2010) Diffusion-driven looping provides a consistent framework for chromatin organization. PLoS ONE 5: e12218.). We show that compaction can be explained by selectively decreasing the number of short-range loops, leaving long-range looping unchanged. …”

Supplementary Material for: Effect of photoperiod and illuminance on daily activity patterns, physiology and NPY peptide expression in migratory redheaded buntings (Emberiza brunic... by Gupta P. (4106764)

“…NPY neuropeptide expression on the periphery of the n. rotundus (pROT), suggests its potential role in visual acuity, where the NPY-cell count significantly decreased under 25 lux illumination. Conclusion We demonstrate that migrating birds may also experience physiological effects from changes in daytime illumination. …”

Table_1_Osmoregulation in Barnacles: An Evolutionary Perspective of Potential Mechanisms and Future Research Directions.DOCX by Kristina Sundell (1555405)

“…Tolerance to low salinities may play a crucial role in determining future distributions of barnacles since forthcoming climate-change scenarios predict decreased salinity in shallow coastal areas. Finally, we outline future research directions to identify osmoregulatory tissues, characterize physiological and molecular mechanisms, and explore ecological and evolutionary implications of osmoregulation in barnacles.…”

Data_Sheet_1_The Aha! experience is associated with a drop in the perceived difficulty of the problem.docx by Nadezhda V. Moroshkina (12904751)

“…To test our hypotheses, we developed a novel set of rebus puzzles. A total of 160 participants solved rebuses and provided initial (within 5 s of problem presentation) and retrospective difficulty ratings (following the generation or presentation of a correct solution). …”

Video_1_Specific Increase of Hippocampal Delta Oscillations Across Consecutive Treadmill Runs.MP4 by Alan M. B. Furtunato (9013835)

“…Within running periods, we observed progressive increases in delta band power along with decreases in the power of the theta and gamma bands across runs. …”

Data_Sheet_1_Specific Increase of Hippocampal Delta Oscillations Across Consecutive Treadmill Runs.PDF by Alan M. B. Furtunato (9013835)

“…Within running periods, we observed progressive increases in delta band power along with decreases in the power of the theta and gamma bands across runs. …”

Integrated analysis reveals important differences in the gut and oropharyngeal microbiota between children with mild and severe hand, foot, and mouth disease by Nan Zhang (46264)

“…Gut microbiota bacterial profiles observed in the acute and convalescent phases resembled each other but differed from those in mild cases. Additionally, 50% of patients with severe HFMD in the acute phase harboured a dominant pathobiontic bacterial genus. …”

Image_1_Radiation upregulates macrophage TREM-1 expression to exacerbate injury in mice.tif by Satoshi Yamaga (15344251)

“…Moreover, CIRP-/- mice exhibited increased survival after 6.5-Gy TBI compared to WT mice. Interestingly, TREM-1 expression on peritoneal macrophages in CIRP-/- mice was significantly decreased compared to that in WT mice at 24 h after 10-Gy TBI. …”

Datasheet1_Multicenter review of a tadalafil suspension formulation for infants and children with pulmonary hypertension: A North American experience.pdf by David Edward Youssef (14501636)

“…The suspension formulation was necessary for 103 (66.9%) patients due to an inability to take enteral tablets and for 49 (31.8%) due to a need for feeding via gastric or jejunal tubes. We observed a statistically significant increase in tricuspid annular plane systolic excursion as well as significant decreases in right-ventricular systolic pressure and NT-proBNP. …”

Image10_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…Further understanding of this question is hampered by the poorly studied mechanisms underlying PDIA1 expression regulation. Here, we showed that PDIA1 mRNA and protein levels were upregulated (average 5-fold) in the intima and media/adventitia following partial carotid ligation (PCL). …”

Image3_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…Further understanding of this question is hampered by the poorly studied mechanisms underlying PDIA1 expression regulation. Here, we showed that PDIA1 mRNA and protein levels were upregulated (average 5-fold) in the intima and media/adventitia following partial carotid ligation (PCL). …”

Trends in Incidence of Stroke and Transition of Stroke Subtypes in Rural Tianjin China: A Population-Based Study from 1992 to 2012 by Bin Li (39349)

“…The proportion of intracerebral hemorrhage was stable overall, increased among men aged 45–64 years, and decreased among men aged ≥65 years. The average age of intracerebral hemorrhage in men reduced by 7.5 years from 1992 to 2012.…”

Image4_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…Further understanding of this question is hampered by the poorly studied mechanisms underlying PDIA1 expression regulation. Here, we showed that PDIA1 mRNA and protein levels were upregulated (average 5-fold) in the intima and media/adventitia following partial carotid ligation (PCL). …”

Image9_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…Further understanding of this question is hampered by the poorly studied mechanisms underlying PDIA1 expression regulation. Here, we showed that PDIA1 mRNA and protein levels were upregulated (average 5-fold) in the intima and media/adventitia following partial carotid ligation (PCL). …”

Image11_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…Further understanding of this question is hampered by the poorly studied mechanisms underlying PDIA1 expression regulation. Here, we showed that PDIA1 mRNA and protein levels were upregulated (average 5-fold) in the intima and media/adventitia following partial carotid ligation (PCL). …”

Image8_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…Further understanding of this question is hampered by the poorly studied mechanisms underlying PDIA1 expression regulation. Here, we showed that PDIA1 mRNA and protein levels were upregulated (average 5-fold) in the intima and media/adventitia following partial carotid ligation (PCL). …”

Presentation1_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.pdf by Leonardo Y. Tanaka (18306715)

“…Further understanding of this question is hampered by the poorly studied mechanisms underlying PDIA1 expression regulation. Here, we showed that PDIA1 mRNA and protein levels were upregulated (average 5-fold) in the intima and media/adventitia following partial carotid ligation (PCL). …”

Antihypertensive Medication Classes Used among Medicare Beneficiaries Initiating Treatment in 2007–2010 by Shia T. Kent (463112)

“…</p><p>Methods and Findings</p><p>We used the 5% random Medicare sample to study the initiation of antihypertensive medication between 2007 and 2010. …”

Image2_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…Further understanding of this question is hampered by the poorly studied mechanisms underlying PDIA1 expression regulation. Here, we showed that PDIA1 mRNA and protein levels were upregulated (average 5-fold) in the intima and media/adventitia following partial carotid ligation (PCL). …”

Image7_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…Further understanding of this question is hampered by the poorly studied mechanisms underlying PDIA1 expression regulation. Here, we showed that PDIA1 mRNA and protein levels were upregulated (average 5-fold) in the intima and media/adventitia following partial carotid ligation (PCL). …”