Image_1_Time dependent effects of prolonged hyperglycemia in zebrafish brain and retina.jpeg by Cassie J. Rowe (13388265)

“…After 8-weeks, RelA, GAD, and TH were significantly elevated in both tissues; IKK and GFAP levels were also elevated, though not significantly. ZO-1 and claudin-5 levels osmotically decreased in retina but displayed an increasing trend in glucose-treated brains. …”

Image_3_Time dependent effects of prolonged hyperglycemia in zebrafish brain and retina.jpeg by Cassie J. Rowe (13388265)

“…After 8-weeks, RelA, GAD, and TH were significantly elevated in both tissues; IKK and GFAP levels were also elevated, though not significantly. ZO-1 and claudin-5 levels osmotically decreased in retina but displayed an increasing trend in glucose-treated brains. …”

Glucose-Dependent Insulin Secretion in Pancreatic β-Cell Islets from Male Rats Requires Ca²⁺ Release via ROS-Stimulated Ryanodine Receptors by Paola Llanos (750250)

“…Inhibitory ryanodine significantly decreased H₂O₂-stimulated insulin secretion and prevented the 4.5-fold increase of cytoplasmic [Ca²⁺] produced by incubation of dissociated β-cells with H₂O₂. …”

Data_Sheet_1_IgG Fc Glycosylation Patterns of Preterm Infants Differ With Gestational Age.PDF by Nele Twisselmann (6242783)

“…Extremely low gestational age infants (born < 28 weeks of gestation during second trimester) had reduced IgG concentrations and decreased proportions of galactosylated (84.5 vs. 88.4%), sialylated (14.5 vs. 17.9%) and bisecting N-acetylglucosamine-containing (8.4 vs. 10.8%) IgG Fc N-linked glycans as compared to preterm infants born ≥28 weeks of gestation (during third trimester) and term infants. …”

Table_1_Time dependent effects of prolonged hyperglycemia in zebrafish brain and retina.docx by Cassie J. Rowe (13388265)

“…After 8-weeks, RelA, GAD, and TH were significantly elevated in both tissues; IKK and GFAP levels were also elevated, though not significantly. ZO-1 and claudin-5 levels osmotically decreased in retina but displayed an increasing trend in glucose-treated brains. …”

Image2_Molecular subtyping of acute myeloid leukemia through ferroptosis signatures predicts prognosis and deciphers the immune microenvironment.TIF by Denggang Fu (5082062)

“…<p>Acute myeloid leukemia (AML) is one of the most aggressive hematological malignancies with a low 5-year survival rate and high rate of relapse. …”

Image3_Club cell CREB regulates the goblet cell transcriptional network and pro-mucin effects of IL-1B.pdf by Mariana Sponchiado (839738)

“…Secondarily, we studied human “club cell-like” H322 cells.</p><p>Results: IL-1B increased whole lung mRNA of secreted (Mucin 5ac, Mucin 5b) and tethered (Mucin 1, Mucin 4) mucins independent of genotype. …”

Table2_Club cell CREB regulates the goblet cell transcriptional network and pro-mucin effects of IL-1B.pdf by Mariana Sponchiado (839738)

“…Secondarily, we studied human “club cell-like” H322 cells.</p><p>Results: IL-1B increased whole lung mRNA of secreted (Mucin 5ac, Mucin 5b) and tethered (Mucin 1, Mucin 4) mucins independent of genotype. …”

Data Sheet 4_Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta‐analysis.pdf by Kai Luo (769190)

“…The one-year OS (OR = 0.71, 95% CI = 0.67-0.75, P < 0.00001) and five-year OS (OR = 0.60, 95% CI = 0.45-0.79, P = 0.0003) decreased significantly. …”

Contributive roles of representative diversified or positive selection genes in the virulence and colonization in zebra fish. by Minjun Yang (120481)

“…<p>(A) LD₅₀ values of the wild-type EIB202 (WT) and the null mutants of the indicated genes. …”

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study by Paul S. de Vries (701679)

“…When using a stricter Bonferroni correction for the 1000G GWA study (<i>P</i>-value < 2.5×10⁻⁸), the number of loci significant only using HapMap imputation increased to 4 while the number of loci significant only using 1000G decreased to 5. …”

Application of AIMEE to export normalized expression data for downstream analysis. by Jonah N. Cullen (5394503)

The Expression of miR-375 Is Associated with Carcinogenesis in Three Subtypes of Lung Cancer by Yi Jin (38575)

“…Moreover, we performed dual luciferase reporter assay and Western blot on 6 targeted genes (<i>FZD8</i>, <i>ITGA10</i>, <i>ITPKB</i>, <i>LRP5</i>, <i>PIAS1</i> and<i>RUNX1</i>) in small cell lung carcinoma cell line NCI-H82. …”

DataSheet1_EPM2A acts as a protective factor in prostate cancer, evidence from a real-world patient cohort.docx by Qintao Ge (13817716)

“…The nomogram containing the EPM2A group, T stage and Gleason score showed a preferable prognostic value (AUC = 0.755; Hosmer‒Lemeshow, p = 0.486). In validation, we confirmed the lower transcript level of EPM2A in PCA than in normal tissues (120.5 ± 2.159 vs. 138.3 ± 1.83, p = 0.035) and correlated it with the expression level of PD-1 (R = 0.283). …”

DataSheet_1_Mechanism Study of the Protective Effects of Sodium Tanshinone IIA Sulfonate Against Atorvastatin-Induced Cerebral Hemorrhage in Zebrafish: Transcriptome Analysis.docx by Zhong-Yan Zhou (6592862)

“…In our previous study, we established a zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area, although the underlying mechanism was not fully elucidated. …”

Compound C6 and C2 impair La binding to different RNA substrates. by Gunhild Sommer (13580)

“…All fluorescence labeled RNA oligoribonucleotides were used at a concentration of 50 nM. All experiments were performed at least twice.…”

Trademark gene expression patterns of human psoriasis and expression of orthologous genes in mouse psoriasiform phenotypes. by William R. Swindell (175427)

“…<p>Genome wide expression data from human psoriatic skin samples (<i>n</i> = 58 patients) and normal skin (<i>n</i> = 64 subjects) was analyzed to identify (A) the 50 genes most strongly increased in human psoriasis and (B) the 50 genes most strongly decreased in human psoriasis (both lists exclude any psoriasis-increased or psoriasis-decreased human gene that lacks an orthologous mouse gene). …”

Data Sheet 1_2D speckle-tracking echocardiography assessment of left atrial and left ventricular mechanics: outcomes in patients with atrial fibrillation treated with hybrid ablati... by Andrea Maria Paparella (20865617)

“…Left atrium (LA) and Left ventricle (LV) mechanics were analyzed, with the following measures obtained at baseline, post-ablation, and follow-up: 1) volumes (EDV, ESV); 2) ejection fraction (EF); 3) strain (ENDO GCS, ENDO GLS); 4) forces (LVLF, LVsysLF, LVim, LVs).</p>Results<p>A total of 50 patients were included. At follow-up, LAEDV decreased from baseline [44.7 mL vs 53.8 mL, P = 0.025]. …”

DataSheet_1_Based on machine learning algorithms for estimating leaf phosphorus concentration of rice using optimized spectral indices and continuous wavelet transform.pdf by Yi Zhang (9093)

“…To obtain the LPC and leaf spectra reflectance, the pot experiments with four phosphorus (P) treatments and two rice cultivars were carried out in a greenhouse in 2020-2021. The results indicated that P deficiency increased leaf reflectance in the visible region (350-750 nm) and decreased the reflectance in the near-infrared (NIR, 750-1350 nm) regions compared to the P-sufficient treatment. …”

Loss of ARHGEF2 function inhibits neurogenesis and increases neural precursors <i>in vitro</i> and <i>in vivo</i>. by Ethiraj Ravindran (790330)

“…<p><b>(A)</b> Cultured mouse cortical precursor cells were transfected with mouse <i>Arhgef2</i> shRNA (<i>shArhgef2</i>) or scramble shRNA (<i>shCon</i>), with a nuclear EGFP plasmid and with either an empty vector (EV), wildtype (wt) or mutant (mut) human <i>ARHGEF2</i>. …”