Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration by Victoria Begley (4670281)

“…RNA pol II profiles at 5ʹ exhibited significant alterations that were compatible with decreased elongation rates in the absence of Xrn1. …”

Data_Sheet_2_Analysis of gut microbiome composition, function, and phenotype in patients with osteoarthritis.docx by Su Liu (1965895)

“…Prevotella could distinguish between OA patients and healthy people with a better diagnostic power (AUC = 77.5%, p < 0.001, 95% CI: 66.9–88.1%). The functions of DNA transcription, amino acid metabolism (including histidine, lysine, and isoleucine), ATP metabolism, and phospholipid metabolism significantly decreased, while glucose metabolism, protein acetylation, and aspartate kinase activity significantly increased in the OA group. …”

Gene expression and metabolite profiling of gibberellin biosynthesis during induction of somatic embryogenesis in <i>Medicago truncatula</i> Gaertn by Rafał Igielski (4281487)

“…Moreover, by analyzing expression of <i>MtBBM</i>, SE marker gene, we confirmed the inhibitory effect of manipulation in GA_s metabolism, applying exogenous GA₃, which not only impaired the production of somatic embryos, but also significantly decreased expression of this gene.…”

Data_Sheet_3_Analysis of gut microbiome composition, function, and phenotype in patients with osteoarthritis.docx by Su Liu (1965895)

“…Prevotella could distinguish between OA patients and healthy people with a better diagnostic power (AUC = 77.5%, p < 0.001, 95% CI: 66.9–88.1%). The functions of DNA transcription, amino acid metabolism (including histidine, lysine, and isoleucine), ATP metabolism, and phospholipid metabolism significantly decreased, while glucose metabolism, protein acetylation, and aspartate kinase activity significantly increased in the OA group. …”

Intragenic <i>ERG</i> Deletions Do Not Explain the Biology of <i>ERG</i>-Related Acute Lymphoblastic Leukemia by Eliska Potuckova (525220)

“…They represent the only genetic lesion described so far present in the majority of cases clustering into a subgroup of B-other subtype characterized by a unique gene expression profile, probably sharing a common, however, not yet fully described, biological background. We aimed to elucidate whether <i>ERG</i> deletions could drive the specific biology of this <i>ERG</i>-related leukemia subgroup through expression of aberrant or decreased expression of wild type <i>ERG</i> isoforms. …”

Table_3_Seasonal Hypometabolism in Female Moose.DOCX by Anne Randi Græsli (8800793)

“…We documented seasonal differences in T_b, HR and activity of moose, with lower levels during winter and higher values during summer. …”

Image_2_Aberrant Expression of Cardiac Troponin-T in Lung Cancer Tissues in Association With Pathological Severity.TIF by Toshihiro Tsuruda (90244)

“…In addition, frequency of positive staining for TNNT2 increased with pleural (χ² = 5.877, P = 0.015) and vascular (χ² = 2.449, P = 0.118) invasions but decreased with lymphatic invasion (χ² = 3.288, P = 0.070) in specimens performed surgical resection. …”

Additive Effects of Millimeter Waves and 2-Deoxyglucose Co-Exposure on the Human Keratinocyte Transcriptome by Yonis Soubere Mahamoud (2967282)

“…We found that the 2dG treatment decreased the cellular ATP content and induced a high modification in the transcriptome (632 coding genes). …”

Data_Sheet_1_Analysis of gut microbiome composition, function, and phenotype in patients with osteoarthritis.xlsx by Su Liu (1965895)

“…Prevotella could distinguish between OA patients and healthy people with a better diagnostic power (AUC = 77.5%, p < 0.001, 95% CI: 66.9–88.1%). The functions of DNA transcription, amino acid metabolism (including histidine, lysine, and isoleucine), ATP metabolism, and phospholipid metabolism significantly decreased, while glucose metabolism, protein acetylation, and aspartate kinase activity significantly increased in the OA group. …”

Table 2_Nonlinear relationship between fibrinogen-to-albumin ratio and mortality in critically ill patients with sepsis: a retrospective cohort study.xlsx by Daishan Jiang (10221338)

“…</p>Results<p>In our analysis of 4,615 sepsis patients, we observed that mortality risk initially decreased with increasing FAR values, reaching a minimum at approximately 94.5*10⁻³, before rising again. …”

Association between breastfeeding and eczema during childhood and adolescence: A cohort study by Jingying Wang (4458820)

“…</p><p>Methods</p><p>In the prospective, population-based Leicester Respiratory Cohort study, we assessed duration of breastfeeding in children aged 1–4 years. …”

FluMart Data from 2018 to 2022. by Smriti Shrestha (21212910)

“…Notably, one case of Influenza A/H5N1 was reported in 2019. This study shows that the influenza positivity rate decreased substantially after the COVID-19 pandemic began, possibly due to the stringent public health and social measures implemented during the pandemic. …”

Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 Has a Therapeutic Potential and Sensitizes Cisplatin in Nasopharyngeal Carcinoma by Fen Yang (287005)

“…To ascertain a therapeutical approach of nasopharyngeal carcinoma (NPC), we hypothesized NVP-BEZ235, a novel and potent imidazo[4,5-c] quinolone derivative, that dually inhibits both PI3K and mTOR kinases activities, had antitumor activity in NPC. …”

Table_4_Longitudinal High-Throughput Sequencing of the T-Cell Receptor Repertoire Reveals Dynamic Change and Prognostic Significance of Peripheral Blood TCR Diversity in Metastatic... by Yi-Tung Chen (6743102)

“…We found that TCRα repertoires, TCRβ repertoires, and CDR3 clonotypes were altered in mCRC patients compared with healthy controls. …”

Table_1_Longitudinal High-Throughput Sequencing of the T-Cell Receptor Repertoire Reveals Dynamic Change and Prognostic Significance of Peripheral Blood TCR Diversity in Metastatic... by Yi-Tung Chen (6743102)

“…We found that TCRα repertoires, TCRβ repertoires, and CDR3 clonotypes were altered in mCRC patients compared with healthy controls. …”

Consensus Micro RNAs Governing the Switch of Dormant Tumors to the Fast-Growing Angiogenic Phenotype by Nava Almog (137631)

“…Considering microRNAs (miRs) as master regulators of transcriptome, we sought to investigate their role in the control of tumor dormancy. …”

DataSheet1_Adaptive Fusion of Multi-Source Tropospheric Delay Estimates for InSAR Deformation Measurements.docx by Li Zhang (8200)

“…In this study, based on our previous fusion of delays predicted by multiple weather models (FDWM), we propose a new approach of adaptive fusion of multi-source tropospheric delay (AFMTD) estimates derived from multiple models over wide areas, i.e., ERA5, GACOS, WRF, MERRA2, NARR, MODIS, Linear model, and Powerlaw model. …”

MicroRNA-32 promotes calcification in vascular smooth muscle cells: Implications as a novel marker for coronary artery calcification by Jianghua Liu (170107)

“…According to microarray analysis, we observed increased expression of miR-125b, miR-30a, and miR-32 and decreased expression of miR-29a, miR-210, and miR-320 during the progression of vascularcalcification. …”

Sex-Specific Embryonic Gene Expression in Species with Newly Evolved Sex Chromosomes by Susan E. Lott (230681)

“…To better understand the developmental constraints on sex chromosome gene expression and evolution, we sequenced mRNA from individual male and female embryos of <i>D. pseudoobscura</i> and <i>D. miranda</i>, from ∼0.5 to 8 hours of development. …”

Image_1_Aberrant Expression of Cardiac Troponin-T in Lung Cancer Tissues in Association With Pathological Severity.TIF by Toshihiro Tsuruda (90244)

“…In addition, frequency of positive staining for TNNT2 increased with pleural (χ² = 5.877, P = 0.015) and vascular (χ² = 2.449, P = 0.118) invasions but decreased with lymphatic invasion (χ² = 3.288, P = 0.070) in specimens performed surgical resection. …”