The core model with an additional intracellular feedback is superior and gene expression upon downregulation of IRF family members. by Katharina Robichon (8445099)

“…(<b>H</b>) Gene expression upon decreased <i>IRF8</i> expression. Huh7.5 cells were incubated with 50 nM siRNA directed against <i>IRF8</i> (red), against <i>IRF8</i> and <i>IRF2</i> (lilac) or non-targeting control (blue) for 24 hours, and then treated with 500 U/ml IFNα. …”

Effect of adipose-derived stem cells (ASCs) on cytokine levels in the lung draining lymph nodes. by Kyu-Sup Cho (770125)

Evaluation of choroidal and retinal thickness measurements in adult hemodialysis patients using spectral-domain optical coherence tomography by Ali Kal (5766140)

“…Choroidal thickness was measured perpendicularly from the outer edge of the retinal pigment epithelium to the choroid-sclera boundary at the fovea and at five additional points: 500 µm and 1000 µm nasal to the fovea and 500 µm, 1000 µm, and 1500 µm temporal to the fovea. …”

Measuring the development of a medical professional identity through medical school by P. Lusk (17328946)

“…Distribution of PIE stage scores across time points were analyzed in the aggregate and individual students were classified as Increase, Stable (no score change) or Decrease based on the trajectories of PIE stage scores over time.…”

RNAi-mediated knockdown of <i>AjAPN1</i> transcript and its encoded protein. by Thuirei Jacob Ningshen (485260)

“…<p>Third instar larvae were intrahemocoelically injected with target and control gene siRNA duplexes at dose of 5 µg/100 mg body weight followed by analyses of target gene/protein expression level at different time points. …”

Simvastatin Inhibits Glucose Metabolism and Legumain Activity in Human Myotubes by Robert Smith (2450401)

“…In addition, simvastatin caused a decrease in maturation and activity of legumain. Dysregulation of glucose metabolism and decreased legumain activity by simvastatin points out new knowledge about the effects of statins on skeletal muscle, and may contribute to the understanding of the myotoxicity observed by statins.…”

Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection by Zizhang Sheng (280791)

“…We also analyzed the presence of AID hotspots and coldspots at different points in lineage development and observed an average decrease in mutability of less than 10 percent over time. …”

Supplementary file 1_Estimating a minimum clinically important difference for the Developmental Behaviour Checklist – parent report.docx by Daniel L. Sutherland (22061309)

“…</p>Results<p>21 studies were included in the meta-analyses and indicated an average DBC total raw score decrease of 3.01 or 4.73 (depending on analytic methods) in randomised controlled trials, and an average decrease of 9.16 points in pre-post designs. …”

Mitoflashes are switched to lower ΔF/F₀ amplitude and R-type mitoflashes in dystrophin morphants. by Meiling Zhang (352540)

“…Note the diminished birefringence in a dys-MO morphant. Lower: statistic of the mean birefringence intensity between the two groups. …”

Septin 7 localization is perturbed by TTFields. by Nidhi Gera (528784)

“…The ratio of the average intensity of Septin 7 staining at midline that of the total staining within the cell in Sham (n = 10) and presence of TTFields at 150kHz (n = 9) or 500kHz (n = 8) showed a significant decrease in Septin accumulation at the midlines in cells treated with 150 kHz TTFields (<b>C</b>). …”

DataSheet1_Biochemical characterization of L-asparaginase isoforms from Rhizobium etli—the boosting effect of zinc.pdf by Joanna Sliwiak (18006655)

“…The activity of ReAIV has a temperature optimum at 45°C–55°C, whereas the activity of ReAV, after reaching its optimum at 37°C, decreases dramatically at 45°C. …”

Effect of antenatal class attendance on fear of childbirth and antenatal stress by Selda Yörük (15298001)

“…The mean fear of childbirth score of pregnant women was 85.50 ± 19.41 before the training and 76.32 ± 20.52 after the training, and the difference between these scores was significant (p < 0.01). …”

DataSheet1_Modeling the hydrodynamic wake of an offshore solar array in OpenFOAM.pdf by Martin van der Eijk (19498426)

Data_Sheet_1_Maternal Exercise Improves High-Fat Diet-Induced Metabolic Abnormalities and Gut Microbiota Profiles in Mouse Dams and Offspring.DOCX by Liyuan Zhou (5712599)

Presentation_1_Fibroblast growth factor 13-mediated regulation of medium spiny neuron excitability and cocaine self-administration.pdf by Nolan M. Dvorak (9524027)

Tension between hysteresis and biphasic dose-response. by Jeffrey V. Wong (168573)

“…Hysteresis is measured by calculating the path difference 24 hours after an increase in serum from 0.01% or after a decrease from 10%. Biphasic response is measured 36 hours after an increase in MYC synthesis (parameter ke_MC; <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002491#pcbi.1002491.s007" target="_blank">Text S1</a>). …”

Understanding the Spatio-Temporal Response of Coral Reef Fish Communities to Natural Disturbances: Insights from Beta-Diversity Decomposition by Thomas Lamy (783331)

Emergent oscillations in population activity. by Kwangjun Lee (22226994)

The high tolerance to aluminium in crucian carp (<i>Carassius carassius</i>) is associated with its ability to avoid hypoxia by Antonio B. S. Poléo (4169929)

“…The decrease in plasma ions caused a transient increase in haematocrit and water content in muscle tissue, returning to control levels when the ion concentrations stabilised, suggesting that the water balance was restored. …”

Effect of age on chronic inflammation and responsiveness to bacterial and viral challenges by Ingrid Elisia (3214848)

“…Studies with unstimulated blood samples, to measure levels of chronic inflammation, revealed a significant increase with age in IL-12p70, CRP and PGE₂, consistent with the concept of “inflammaging”, and a decrease in G-CSF in both men and women. …”