FOXO4 is a substrate for Mdm2 ubiquitination. by Arjan B. Brenkman (30052)

“…<p>(a) Mdm2 co-expression decreases FOXO protein levels. …”

Discovery of 2‑Aryl-4-aminoquinazolin-Based LSD1 Inhibitors to Activate Immune Response in Gastric Cancer by Bo Wang (86769)

“…Among them, compound Z-1 exhibited the best LSD1 inhibitory activity (IC₅₀ = 0.108 μM). Z-1 also acted as a selective and cellular active as an LSD1 inhibitor. …”

Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors by Russell Fritzemeier (5538416)

“…In vitro studies in HeLa cells demonstrated that <b>16d</b> inhibited S1P release with an IC₅₀ of 1.93 μM. Administration of <b>16d</b> to mice and rats drove significant decreases in circulating lymphocyte counts and plasma S1P concentrations, recapitulating the phenotype observed in mice made deficient in Spns2. …”

Calibration for reproduction and weight gain. by Ahmed Ferchiou (8591607)

“…On average, prevalences were decreased by 24% and 50%, respectively, due to vaccination, which also reduced the 2-day to 1-month mortality rates by 2–3% and 15–17%, respectively. …”

S1 Graphical abstract - by Hai Nguyen Ngoc Dang (19200560)

“…Furthermore, the median aortic compliance (AC, 10^-2mm/mmHg) and aortic distensibility (AD, 10^-3mmHg^-1) in individuals with T2DM were 4.07 (2.28–7.44) and 3.08 (1.57–5.26), respectively, lower than those in the control group, with median values of 6.40 (3.08–10.75) and 5.33 (2.80–9.79). A longer diabetes duration was linked to a greater ASI (r = 0.43, p < 0.05), while the AS decreased (r = -0.37, p < 0.05).…”

Histology of transplant sites in healthy dogs. by Stephen Harrington (12634731)

Postprandial Oxidative Stress and Gastrointestinal Hormones: Is There a Link? by Hana Malinska (618835)

“…Evaluating postprandial changes of gastrointestinal hormones together with changes in oxidative stress markers may help to understand the mechanisms behind the postprandial state in diabetes as well as suggest new preventive and therapeutical strategies.</p><p>Methods</p><p>A standard meal test has been used for monitoring the postprandial concentrations of gastrointestinal hormones and oxidative stress markers in patients with T2D (n = 50) compared to healthy controls (n = 50). …”

Estimated prevalence of delayed ART initiation. by Yan Tao (299924)

“…In subgroup analysis, the estimated pooled prevalence decreased with age. By sex, the prevalence was higher among male patients (39.3%, 95% CI: 32.2–46.4%) than female (36.5%, 95% CI: 26.9–50.7%). …”

Sensitivity analysis. by Yan Tao (299924)

“…In subgroup analysis, the estimated pooled prevalence decreased with age. By sex, the prevalence was higher among male patients (39.3%, 95% CI: 32.2–46.4%) than female (36.5%, 95% CI: 26.9–50.7%). …”

Supplementary Material for: Upregulation of miRNA-26a enhances the apoptosis of cerebral neurons by targeting EphA2 and inhibiting the MAPK pathway by Chi B. (13546486)

S3 File - by Abdullah Niaz (16955618)

“…<div><p>2-Methyl-4-chlorophenoxyacetic acid (MCPA) is a highly mobile herbicide that is frequently detected in global potable water sources. …”

S1 File - by Abdullah Niaz (16955618)

“…<div><p>2-Methyl-4-chlorophenoxyacetic acid (MCPA) is a highly mobile herbicide that is frequently detected in global potable water sources. …”

Key properties of MCPA. by Abdullah Niaz (16955618)

“…<div><p>2-Methyl-4-chlorophenoxyacetic acid (MCPA) is a highly mobile herbicide that is frequently detected in global potable water sources. …”

S2 File - by Abdullah Niaz (16955618)

“…<div><p>2-Methyl-4-chlorophenoxyacetic acid (MCPA) is a highly mobile herbicide that is frequently detected in global potable water sources. …”

Assessing binding site representation across dense arrays. by Virgile Andreani (17087764)

“…<p>(A) For the |<i>R</i>| = 10 randomly generated binding sites of Collection 1 we found 1854 optimal sequences (each fitting 6 binding sites within <i>L</i> = 50 bp). …”

Implementation of a rapid response team in a large nonprofit Brazilian hospital: improving the quality of emergency care through Plan-Do-Study-Act by Meire Cavalieri Almeida (6826961)

“…Results: Between 2013 and 2014, the rapid response team attended to 2,296 patients. This study showed a nonsignificant reduction in mortality from 8.3% in cycle 1 to 5.0% in cycle 4; however, death rates remained stable in cycles 3 and 4, with frequencies of 5.2% and 5.0%, respectively. …”

Implementation of a rapid response team in a large nonprofit Brazilian hospital: improving the quality of emergency care through Plan-Do-Study-Act by Meire Cavalieri Almeida (6826961)

“…Results: Between 2013 and 2014, the rapid response team attended to 2,296 patients. This study showed a nonsignificant reduction in mortality from 8.3% in cycle 1 to 5.0% in cycle 4; however, death rates remained stable in cycles 3 and 4, with frequencies of 5.2% and 5.0%, respectively. …”

The minimal data set. by Wenya Zhu (13957497)

“…However, the extensive use of insecticides poses a significant threat to the survival and efficacy of <i>T. ostriniae</i>. …”

Total thermal resistance changes with the Re. by Yinhang Xi (17973002)

“…The simulation results show that compared with the smooth rectangular mini-channel, after interpolating double S turbulators with different long axial radii (1mm, 1.5mm, 2mm), the average Nusselt number increased by 81.74%~101.74%, 71.29%~94.06%, 67.16%~88.48%, the total thermal resistance decreased by 45.1%~50.72%, 41.72%~48.74%, 40.28%~47.2%, and the number of field synergies increased by 85.58%~111.65%, 74.1%~102.6%, 69.64%~96.12%. …”

The predicted and simulated values compare. by Yinhang Xi (17973002)

“…The simulation results show that compared with the smooth rectangular mini-channel, after interpolating double S turbulators with different long axial radii (1mm, 1.5mm, 2mm), the average Nusselt number increased by 81.74%~101.74%, 71.29%~94.06%, 67.16%~88.48%, the total thermal resistance decreased by 45.1%~50.72%, 41.72%~48.74%, 40.28%~47.2%, and the number of field synergies increased by 85.58%~111.65%, 74.1%~102.6%, 69.64%~96.12%. …”